Compile Data Set for Download or QSAR
Report error Found 110 Enz. Inhib. hit(s) with all data for entry = 9537
TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365211BDBM365211(US9867833, Compound I-110(S) | 4-(9-((4-chloro-1H-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365212BDBM365212(US9867833, Compound I-111(S) | 4-(9-(3,4-difluorop...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365201BDBM365201(US9867833, Compound I-105(S) | (S)-2-[4-(2-((1-met...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365192BDBM365192(US9867833, Compound I-100 | 3-(3-chlorobenzyl)-5-m...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365050BDBM365050(4-(3-benzyl-5-ethyl-4,5- dihydro-3H-1,2,2a1,5- tet...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365047BDBM365047(4-(3-benzyl-3,4-dihydro-5- oxa-1,2,2a1- triazaacen...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365049BDBM365049(4-(3-benzyl-3,4-dihydro-5- thia-1,2,2a1- triazaace...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365042BDBM365042(4-(3-(4-chlorobenzyl)-5- methyl-4,5-dihydro-3H- 1,...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365044BDBM365044(4-(3-(4-chloro-3- fluorobenzyl)-4,5-dihydro- 3H-1,...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365039BDBM365039(4-(3-(4-methoxybenzyl)-4,5- dihydro-3H-1,2,2a1,5- ...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 424933BDBM424933(4-(3-(3-fluoro-4- methoxybenzyl)-4,5- dihydro-3H-1...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 424929BDBM424929(4-(3-benzyl-5-methyl-4,5- dihydro-3H-1,2,2a1,5- te...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 424930BDBM424930(4-(3-isobutyl-4,5-dihydro- 3H-1,2,2a1,5- tetraazaa...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 424927BDBM424927(4-(3-benzyl-4,5-dihydro-3H- 1,2,2a1,5- tetraazaace...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 424928BDBM424928(4-(3-(4-chlorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 424925BDBM424925(4-(3-(4-chlorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 424924BDBM424924(N-(1-methyl-1H-pyrazol-5- yl)-4-(3-phenyl-4,5-dihy...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365073BDBM365073(4-(3-(4-fluorobenzyl)-5- methyl-4,5-dihydro-3H- 1,...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365075BDBM365075(4-(3-(4-chloro-3- fluorobenzyl)-5-methyl-4,5- dihy...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365069BDBM365069(4-(9-((benzyloxy)methyl)- 8,9-dihydro-7H-6-oxa- 1,...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365068BDBM365068(3-benzyl-5-methyl-7-(2-((1- methyl-1H-pyrazol-5- y...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365062BDBM365062(4-(3-((6-methoxypyridin-3- yl)methyl)-4,5-dihydro-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365057BDBM365057(4-(3-(4-fluorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365059BDBM365059(9-(4-chlorobenzyl)-6-methyl- 4-(2-((1-methyl-1H-py...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365105BDBM365105(4-(3-(4-methoxybenzyl)-3,4- dihydro-5-oxa-1,2,2a1-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365101BDBM365101(US9867833, Compound I-55(S) | 4-(3-(4-chlorobenzyl...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365103BDBM365103(4-(3-(3-fluoro-4- methoxybenzyl)-3,4-dihydro- 5-ox...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365097BDBM365097(4-(3-(3-fluoro-4- methoxybenzyl)-3,4-dihydro- 5-ox...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365099BDBM365099(4-(9-((4-chloro-1H-pyrazol-1- yl)methyl)-8,9-dihyd...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365093BDBM365093(4-(3-(4-fluorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1 -...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365095BDBM365095(4-(3-isobutyl-3,4-dihydro-5- oxa-1,2,2a1- triazaac...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365084BDBM365084(9-(4-chlorobenzyl)-6-methyl- 4-(2-((1-methyl-1H-py...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365087BDBM365087(4-(3-(4-chlorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365082BDBM365082(4-(3-benzyl-3,4-dihydro-5- oxa-1,2,2a1- triazaacen...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365078BDBM365078(4-(9-(4-chlorobenzyl)-8,9- dihydro-7H-6-oxa-1,2,2a...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365135BDBM365135(US9867833, Compound I-108(S) | 4-(9-(4-fluoropheno...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365137BDBM365137(9-benzyl-6-methyl-4-(2-((1- methyl-1H-pyrazol-5- y...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365128BDBM365128(9-(4-methoxybenzyl)-6- methyl-4-(2-((1-methyl- 1H-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365130BDBM365130(9-(4-methoxybenzyl)-6- methyl-4-(2-((1-methyl- 1H-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365120BDBM365120(4-(9-(4-fluorobenzyl)-8,9- dihydro-7H-6-oxa-1,2,2a...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365122BDBM365122(US9867833, Compound I-59(S) | 4-(9-(3-fluoro-4- me...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365116BDBM365116(4-(9-((4-cyclopropyl-1H- pyrazol-1-yl)methyl)-8,9-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365118BDBM365118(4-(3-(4-fluorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365107BDBM365107(US9867833, Compound I-52(S) | N-(1-methyl-1H-pyraz...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365110BDBM365110(4-(3-(3,4-difluorobenzyl)-3,4- dihydro-5-oxa-1,2,2...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365160BDBM365160((S)-9-(3-chlorobenzyl)-6- methyl-4-(2-((1-methyl-1...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365161BDBM365161(4-(3-(3-methoxybenzyl)-3,4- dihydro-5-oxa-1,2,2a1-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365154BDBM365154(4-(3-benzyl-4-methyl-3,4- dihydro-5-oxa-1,2,2a1- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365150BDBM365150(9-(2-fluoro-4- methoxybenzyl)-6-methyl-4- (2-((1-m...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365146BDBM365146(4-(3-benzyl-4-methyl-3,4- dihydro-5-oxa-1,2,2a1- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

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