Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 9648
TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478095BDBM478095(1-((3-(2-Chloro-8-cyanoindolizin-5-yl)pyridin-4-yl...)
Affinity DataIC50: 26nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478097BDBM478097(1-((3-(2-bromo-8-cyanoindolizin-5-yl)pyridin- 4-yl...)
Affinity DataIC50: 29nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478096BDBM478096(2-((3-(2-chloro-8-cyanoindolizin-5-yl)pyridin- 4-y...)
Affinity DataIC50: 30nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478084BDBM478084(1-((3-(8-Cyanoindolizin-5-yl)pyridin-4-yl)thio)cyc...)
Affinity DataIC50: 30nMAssay Description:Cells were seeded onto 24-well plates at the density of 2.0×105 cells per well. The cells were incubated at 37° C., 5% CO2 overnight. After approxima...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478092BDBM478092(US10894038, Example 10 | US10894038, Example 24 | ...)
Affinity DataIC50: 34nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478100BDBM478100(1-((3-(8-Cyano-3-fluoroindolizin-5-yl)pyridin-4-yl...)
Affinity DataIC50: 34nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478089BDBM478089(1-((3-(8-cyano-2-(trifluoromethyl)indolizin-5-yl)p...)
Affinity DataIC50: 44nMAssay Description:Cells were seeded onto 24-well plates at the density of 2.0×105 cells per well. The cells were incubated at 37° C., 5% CO2 overnight. After approxima...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478098BDBM478098(1-((3-(2,8-dicyanoindolizin-5-yl)pyridin-4-yl) thi...)
Affinity DataIC50: 45nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478091BDBM478091(1-((3-(5-cyanoindolizin-8-yl)pyridin-4-yl)thio)cyc...)
Affinity DataIC50: 55nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478085BDBM478085(2-((3-(8-cyanoindolizin-5-yl)pyridin-4-yl)thio)-2-...)
Affinity DataIC50: 66nMAssay Description:Cells were seeded onto 24-well plates at the density of 2.0×105 cells per well. The cells were incubated at 37° C., 5% CO2 overnight. After approxima...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478087BDBM478087(2-((3-(1-chloro-8-cyanoindolizin-5-yl)pyridin-4-yl...)
Affinity DataIC50: 68nMAssay Description:Cells were seeded onto 24-well plates at the density of 2.0×105 cells per well. The cells were incubated at 37° C., 5% CO2 overnight. After approxima...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478101BDBM478101(1-((3-(8-Cyano-1 fluoroindolizin-5-yl)pyridin-4-yl...)
Affinity DataIC50: 85nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478102BDBM478102(1-((3-(3-chloro-8-cyanoindolizin-5-yl)pyridin- 4-y...)
Affinity DataIC50: 89nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478088BDBM478088(1-((3-(8-cyano-2-methylindolizin-5-yl)pyridin-4-yl...)
Affinity DataIC50: 110nMAssay Description:Cells were seeded onto 24-well plates at the density of 2.0×105 cells per well. The cells were incubated at 37° C., 5% CO2 overnight. After approxima...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478094BDBM478094(1-((3-(5-cyano-2-fluoroindolizin-8-yl)pyridin-4- y...)
Affinity DataIC50: 271nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478086BDBM478086(2-((3-(3-chloro-8-cyanoindolizin-5-yl)pyridin-4-yl...)
Affinity DataIC50: 282nMAssay Description:Cells were seeded onto 24-well plates at the density of 2.0×105 cells per well. The cells were incubated at 37° C., 5% CO2 overnight. After approxima...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478099BDBM478099(1-((3-(8-cyano-2-(methylsulfonyl)indolizin-5- yl)p...)
Affinity DataIC50: 332nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478092BDBM478092(US10894038, Example 10 | US10894038, Example 24 | ...)
Affinity DataIC50: 424nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478104BDBM478104(2-((3-(8-cyanoindolizin-5-yl)pyridin-4-yl)thio)- 3...)
Affinity DataIC50: 504nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 478093BDBM478093(1-((3-(2-chloro-5-cyanoindolizin-8-yl)pyridin- 4-y...)
Affinity DataIC50: 828nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent