Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 9657
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479328BDBM479328((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 2nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479344BDBM479344((3-((3S,4)S-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 2.30nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479347BDBM479347((3-((S)-5-amino-5,7-dihydrospiro[cyclo- penta[b]py...)
Affinity DataIC50: 2.70nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479312BDBM479312(US10894797, Compound 1 | (3-((3S,4S)-4-amino-3-met...)
Affinity DataIC50: 3nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479327BDBM479327((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 3nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479359BDBM479359((3-((S)-5-amino-5,7-dihydro- spiro[cyclopenta[b]py...)
Affinity DataIC50: 3.30nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479361BDBM479361((3-((3S,4S)-4-amino-3-methyl-2-oxa- 8-azaspiro[4.5...)
Affinity DataIC50: 3.5nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479340BDBM479340((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 3.60nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479363BDBM479363((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 3.70nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479341BDBM479341((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 3.80nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479357BDBM479357((S)-1'-(5-(((6aS,8S)-8-((methoxy- methoxy)methyl)-...)
Affinity DataIC50: 3.90nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479312BDBM479312(US10894797, Compound 1 | (3-((3S,4S)-4-amino-3-met...)
Affinity DataIC50: 4nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479343BDBM479343((3-((3S,4S)-4-amino-3-methyl-2-oxa- 8-azaspiro[4.5...)
Affinity DataIC50: 4nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479348BDBM479348((3-((S)-5-amino-5,7-dihydrospiro[cyclo- penta[b]py...)
Affinity DataIC50: 4.20nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479342BDBM479342((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 4.20nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479354BDBM479354((3S,4S)-8-(5-(((6aS,8S)-8-(methoxymethyl)-6a,7,8,9...)
Affinity DataIC50: 4.5nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479362BDBM479362((3-((3S,4S)-4-amino-3-methyl-2-oxa- 8-azaspiro[4.5...)
Affinity DataIC50: 4.90nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479352BDBM479352((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 5nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479315BDBM479315((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 5nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479325BDBM479325((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 5nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479349BDBM479349((3-((S)-5-amino-13-oxa-9- azadispiro[3.1.56.24]tri...)
Affinity DataIC50: 5.70nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479351BDBM479351((3-((3S,4S)-4-amino-3-methyl- 2-oxa-8-azaspiro[4.5...)
Affinity DataIC50: 5.90nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479355BDBM479355((3S,4S)-8-(6-amino-5-(((6aS,8S)-8-((methoxymeth- o...)
Affinity DataIC50: 5.90nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479353BDBM479353((3S,4S)-8-(5-(((6aS,8S)-8-((methoxymethoxy)methyl)...)
Affinity DataIC50: 5.90nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479318BDBM479318((6aS,8S)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...)
Affinity DataIC50: 6nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479317BDBM479317((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 6nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479333BDBM479333((6aS,8S)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...)
Affinity DataIC50: 6nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479345BDBM479345((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 6.20nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479350BDBM479350((3-((S)-5-amino-13-oxa-9- azadispiro[3.1.56.24]tri...)
Affinity DataIC50: 7nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479320BDBM479320((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 8nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479319BDBM479319((6aS,8R)-4-((5-((3S,4S)-4-amino-3-methyl-2oxa-8- a...)
Affinity DataIC50: 8nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479334BDBM479334((6aS,8R)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...)
Affinity DataIC50: 8nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479316BDBM479316((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 8nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479330BDBM479330((6aS,8R)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...)
Affinity DataIC50: 8nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479324BDBM479324((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 8nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479338BDBM479338((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 8nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479358BDBM479358((S)-1'-(6-amino-5-(((6aS,8S)-8-((methoxy- methoxy)...)
Affinity DataIC50: 8.40nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479356BDBM479356((3S,4S)-8-(6-amino-5-(((6aS,8S)-8-(methoxymethyl)-...)
Affinity DataIC50: 9.40nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479335BDBM479335((6-(((6aS,8S)-8-(1H-pyrazol-1-yl)-6a,7,8,9-tetrahy...)
Affinity DataIC50: 10nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479326BDBM479326((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 10nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479337BDBM479337((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 10nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479321BDBM479321((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 10nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479336BDBM479336((6-(((6aS,84R)-8-(1H-pyrazol-1-yl)-6a,7,8,9-tetrah...)
Affinity DataIC50: 11nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479331BDBM479331((6aS,8S)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...)
Affinity DataIC50: 11nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479360BDBM479360((3-((3S,4S)-4-amino-3-methyl-2-oxa- 8-azaspiro[4.5...)
Affinity DataIC50: 12nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479323BDBM479323((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azasprio[4.5...)
Affinity DataIC50: 12nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479332BDBM479332((3-((3S,4S)-4-amino-3-methyl-2-oxa- 8-azaspiro[4.5...)
Affinity DataIC50: 13nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479314BDBM479314((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: 13nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479329BDBM479329((6aS,8S)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...)
Affinity DataIC50: 13nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 479339BDBM479339(4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[...)
Affinity DataIC50: 13nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

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