Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 9686
TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481715BDBM481715(US10913733, Example 26)
Affinity DataKi:  0.0750nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481707BDBM481707(N-(5-((4-(4-(N,N- dimethylsulfamoyl) benzylidene)p...)
Affinity DataKi:  0.0950nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481720BDBM481720(US10913733, Example 31)
Affinity DataKi:  0.117nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481715BDBM481715(US10913733, Example 26)
Affinity DataKi:  0.167nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481739BDBM481739(US10913733, Example 50)
Affinity DataKi:  0.241nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481711BDBM481711(N-(5-((4-((1-oxoisoindolin- 5-yl)methylene)piperid...)
Affinity DataKi:  0.268nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481727BDBM481727((S,Z)-N-(5-((4-(4- methoxybenzylidene)-2- methylpi...)
Affinity DataKi:  0.287nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481698BDBM481698(4-((1-((2-acetamidothiazol- 5-yl)methyl)-piperidin...)
Affinity DataKi:  0.294nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481718BDBM481718(US10913733, Example 29)
Affinity DataKi:  0.324nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481697BDBM481697(N-(5-((4-((1H-pyrazol-4- yl)methylene)piperidin-1-...)
Affinity DataKi:  0.387nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481741BDBM481741(US10913733, Example 54 | US10913733, Example 52)
Affinity DataKi:  0.389nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481600BDBM481600(US10913733, Example 1)
Affinity DataKi:  0.392nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481716BDBM481716(US10913733, Example 27)
Affinity DataKi:  0.411nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481708BDBM481708(N-(5-{[4-(1H-indol-5- ylmethylidene)piperidin-1- y...)
Affinity DataKi:  0.427nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481719BDBM481719(US10913733, Example 30)
Affinity DataKi:  0.430nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481699BDBM481699(2-(3-((1-((2- acetamidothiazol-5- yl)methyl)-piper...)
Affinity DataKi:  0.614nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481731BDBM481731(US10913733, Example 42)
Affinity DataKi:  0.625nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481712BDBM481712(N-[5-({4-[(4-hydroxy-3- methoxyphenyl)methylidene]...)
Affinity DataKi:  0.634nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481695BDBM481695(N-[5-({4-[(6-aminopyridin- 3-yl)methylidene]piperi...)
Affinity DataKi:  0.635nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481696BDBM481696(N-(5-((4-(3- (hydroxymethyl) benzylidene)piperidin...)
Affinity DataKi:  0.690nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481701BDBM481701(US10913733, Example 12)
Affinity DataKi:  0.703nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481702BDBM481702(N-(5-((4-(4- methylbenzylidene)piperidin- 1-yl)met...)
Affinity DataKi:  0.741nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481692BDBM481692(US10913733, Example 4 | US10913733, Example 3)
Affinity DataKi:  0.861nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481709BDBM481709(N-(5-{[4-(1,3-benzodioxol- 5-ylmethylidene)piperid...)
Affinity DataKi:  1.03nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481723BDBM481723((S,Z)-N-(5-{(4-benzylidene-2- methylpiperidin-1- y...)
Affinity DataKi:  1.04nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481692BDBM481692(US10913733, Example 4 | US10913733, Example 3)
Affinity DataKi:  1.09nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481733BDBM481733(N-(5-((4-(3- hydroxybenzylidene)piperidin- 1-yl)me...)
Affinity DataKi:  1.13nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481714BDBM481714(methyl 4-((1-((2- acetamidothiazol-5- yl)methyl)pi...)
Affinity DataKi:  1.37nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481704BDBM481704(N-(5-((4-(4- ethoxybenzylidene)piperidin- 1-yl)met...)
Affinity DataKi:  1.45nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481713BDBM481713(N-[5-({4-[(3-hydroxy-4- methoxyphenyl)methylidene]...)
Affinity DataKi:  1.51nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481738BDBM481738(US10913733, Example 49)
Affinity DataKi:  1.60nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481722BDBM481722(N-(5-{[4-(phenyl- methylidene)piperidin-1- yl]meth...)
Affinity DataKi:  1.75nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481710BDBM481710(N-(5-{[4-(2,3-dihydro-1,4- benzodioxin-6- ylmethyl...)
Affinity DataKi:  1.79nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481735BDBM481735(N-[5-({4-[(4- methoxyphenyl)methylidene] piperidin...)
Affinity DataKi:  2nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481691BDBM481691(US10913733, Example 2)
Affinity DataKi:  2.08nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481736BDBM481736(N-(5-((4-(2- methoxybenzylidene)piperidin- 1-yl)me...)
Affinity DataKi:  2.45nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481721BDBM481721(US10913733, Example 32)
Affinity DataKi:  2.70nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481732BDBM481732(N-(5-((4-(3- methoxybenzylidene)piperidin- 1-yl)me...)
Affinity DataKi:  2.93nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481700BDBM481700(N-(5-((4-(4- (trifluoromethoxy) benzylidene)-piper...)
Affinity DataKi:  3.15nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481705BDBM481705(N-(5-((4-(pyrimidin-5- ylmethylene)piperidin-1- yl...)
Affinity DataKi:  3.37nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481706BDBM481706(N-[5-({4-[(2,3- dimethoxyphenyl)methylidene] piper...)
Affinity DataKi:  3.40nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481694BDBM481694(4-((1-((2-acetamidothiazol- 5-yl)methyl)piperidin-...)
Affinity DataKi:  3.53nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481717BDBM481717(US10913733, Example 28)
Affinity DataKi:  5.71nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481734BDBM481734(N-{5-[(4-{[4-(prop-2-en-1- yloxy)phenyl]methyliden...)
Affinity DataKi:  6.11nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481730BDBM481730((S,E)-N-(5-((4-(4- methoxybenzylidene)-2- methylpi...)
Affinity DataKi:  9.61nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481741BDBM481741(US10913733, Example 54 | US10913733, Example 52)
Affinity DataKi:  11.8nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481726BDBM481726((S,E)-N-(5-((4-benzylidene-2- methylpiperidin-1- y...)
Affinity DataKi:  29.8nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481737BDBM481737(N-(5-((4-([1,1'-biphenyl]-4- ylmethylene)piperidin...)
Affinity DataKi:  53.8nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481724BDBM481724((R,Z)-N-(5-((4-benzylidene-2- methylpiperidin-1- y...)
Affinity DataKi:  56.6nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 481729BDBM481729((R,Z)-N-(5-((4-(4- methoxybenzylidene)-2- methylpi...)
Affinity DataKi:  71.2nMAssay Description:Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

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