Compile Data Set for Download or QSAR
Report error Found 110 Enz. Inhib. hit(s) with all data for entry = 9689
LigandChemical structure of BindingDB Monomer ID 481835BDBM481835(4-[3-[5-[(5-methyl-4-oxo- pyrido[2,3-d]pyrimidin-3...)
Affinity DataIC50: 2.58nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481824BDBM481824(5-[(5-methyl-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)me...)
Affinity DataIC50: 4.76nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481849BDBM481849(trans-3-[[4-[3-(4- chlorophenyl)cyclobutyl]-5- oxo...)
Affinity DataIC50: 4.84nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481792BDBM481792(5-[(5-methyl-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)me...)
Affinity DataIC50: 5nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481844BDBM481844(3-[3-(4- fluorophenyl)cyclobutyl]-5- [(5-methyl-4-...)
Affinity DataIC50: 5.76nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481829BDBM481829(5-[(5-chloro-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)me...)
Affinity DataIC50: 5.88nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481862BDBM481862(3-[3-(4- chlorophenyl)cyclobutyl]-5- [(5-methyl-4-...)
Affinity DataIC50: 6.30nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481841BDBM481841(3-(3-(3- chlorophenoxy)propyl)-5- ((5-methyl-4-oxo...)
Affinity DataIC50: 6.34nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481796BDBM481796(5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[(2S)-2-f...)
Affinity DataIC50: 7nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481848BDBM481848(5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[(1R,3R)-...)
Affinity DataIC50: 8.26nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481786BDBM481786(3-((4-(4-chlorophenethyl)-5- oxo-4,5-dihydro-1,3,4...)
Affinity DataIC50: 9nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481856BDBM481856(5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[(1R,3R)-...)
Affinity DataIC50: 9.59nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481802BDBM481802((R)-3-(2-(4-bromophenyl)-2- fluoroethyl)-5-((7-met...)
Affinity DataIC50: 10nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481818BDBM481818(3-[[4-[3-fluoro-3-(4- fluorophenyl)cyclobutyl]-5- ...)
Affinity DataIC50: 11.2nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481820BDBM481820(trans-3-[3-(3- fluorophenoxy)cyclobutyl]-5- [(7-me...)
Affinity DataIC50: 11.5nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481836BDBM481836(5-[(5-methyl-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)me...)
Affinity DataIC50: 11.9nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481765BDBM481765(3-[2-(4-chlorophenyl)ethyl]- 5-[(5-methyl-4-oxo- p...)
Affinity DataIC50: 12nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481823BDBM481823(5-[(5-methyl-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)me...)
Affinity DataIC50: 12.5nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481764BDBM481764(3-(4-chlorophenethyl)-5-((5- methyl-4-oxopyrido[3,...)
Affinity DataIC50: 13nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481808BDBM481808(3-[3-(4- chlorophenyl)cyclobutyl]-5- [(7-methyl-6-...)
Affinity DataIC50: 14nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481780BDBM481780(1-([4-[2-(4- chlorophenyl)ethyl]-5-oxo- 4,5-dihydr...)
Affinity DataIC50: 14nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481839BDBM481839(3-((4-((trans)-3-(4- chlorophenyl)cyclobutyl)-5- o...)
Affinity DataIC50: 15.2nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481854BDBM481854(trans-3-[3-(4- chlorophenyl)cyclobutyl]-5- [(4-oxo...)
Affinity DataIC50: 16.2nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481850BDBM481850(trans-3-[3-(4-chlorophenyl)-3- fluoro-cyclobutyl]-...)
Affinity DataIC50: 16.8nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481827BDBM481827(trans-3-[3-(3- chlorophenoxy)cyclobutyl]- 5-[(7-me...)
Affinity DataIC50: 17.7nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481868BDBM481868(5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[3-(2- na...)
Affinity DataIC50: 17.8nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481852BDBM481852(3-[3-fluoro-3-(4- fluorophenyl)cyclobutyl]-5- [(5-...)
Affinity DataIC50: 18nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481801BDBM481801(3-(4-chlorophenethyl)-5-((5,7- dimethyl-4-oxoimida...)
Affinity DataIC50: 18nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481798BDBM481798(5-((8-chloro-5-methyl-4- oxopyrido[3,4-d]pyrimidin...)
Affinity DataIC50: 18nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481864BDBM481864(5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[rac-(2R)...)
Affinity DataIC50: 19.1nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481810BDBM481810(3-[3-(4- bromophenyl)cyclobutyl]-5- [(7-methyl-6-o...)
Affinity DataIC50: 20nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481822BDBM481822(trans-2-[[4-[3-(4- chlorophenyl)cyclobutyl]-5- oxo...)
Affinity DataIC50: 21.1nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481833BDBM481833(4-[1-fluoro-3-[5-[(5-methyl-4- oxo-pyrido[2,3-d]py...)
Affinity DataIC50: 21.4nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481816BDBM481816(trans-3-[3-(4- chlorophenyl)cyclobutyl]-5- [(8-deu...)
Affinity DataIC50: 22.6nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481842BDBM481842(1-([4-[3-(3- chlorophenoxy)propyl]-5- oxo-4,5-dihy...)
Affinity DataIC50: 22.6nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481858BDBM481858(3-[3-[(trans)-4- (difluoromethoxy)phenyl] cyclobut...)
Affinity DataIC50: 26nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481788BDBM481788(1-[[3-[2-(4- chlorophenyl)ethyl]-1,2,4- oxadiazol-...)
Affinity DataIC50: 26.6nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481817BDBM481817(trans-3-[3-(4- chlorophenyl)cyclobutyl]-5- [(2-deu...)
Affinity DataIC50: 28.4nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481859BDBM481859(3-[3-(4-chlorophenyl)-3- fluoro-cyclobutyl]-5-[(5-...)
Affinity DataIC50: 29.6nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481861BDBM481861(3-[3-(4-chloro-3-fluoro- phenyl)cyclobutyl]-5-[(7-...)
Affinity DataIC50: 29.9nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481772BDBM481772((R)-3-(2-(4-chlorophenyl)- 2-fluoroethyl)-5-((7-me...)
Affinity DataIC50: 34nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481777BDBM481777((S)-3-(2-(4- chlorophenyl)propyl)-5-((7- methyl-6-...)
Affinity DataIC50: 34nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481790BDBM481790(1-[(4-[2-[4- (difluoromethoxy)phenyl]ethyl]- 5-oxo...)
Affinity DataIC50: 36nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481857BDBM481857(5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[rac-(1R,...)
Affinity DataIC50: 36.1nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481847BDBM481847(5-[[4-[3-(4- chlorophenyl)cyclobutyl]-5- oxo-1,3,4...)
Affinity DataIC50: 36.2nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481815BDBM481815(2-[[4-[3-(4- chlorophenyl)cyclobutyl]-5- oxo-1,3,4...)
Affinity DataIC50: 40.3nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481831BDBM481831(3-[3-fluoro-3-(3- fluorophenyl)cyclobutyl]-5- [(5-...)
Affinity DataIC50: 40.5nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481834BDBM481834(5-[(4-oxopyrido[2,3- d]pyrimidin-3-yl)methyl]-3- [...)
Affinity DataIC50: 40.6nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481770BDBM481770(5-((7-methyl-6-oxo-6H- purin-1(7H)-yl)methyl)-3- (...)
Affinity DataIC50: 41nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 481843BDBM481843(5-methyl-3-[[5-oxo-4-[rac- (2R)-2-(4-chlorophenyl)...)
Affinity DataIC50: 43.8nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

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