Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 9787
TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488635(US10961198, Compound 6.01 | trans-N-(3-(1-Cyclopro...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488634(US10961198, Compound 6 | trans-N-(3-(1-Cyclopropyl...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488633(US10961198, Compound 5.30 | trans-N-((trans-4-(5-C...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488632(US10961198, Compound 5.29 | trans-4-Hydroxy-N-(4-(...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488631(US10961198, Compound 5.28 | (1s, 4s)-4-Hydroxy-N-(...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488630(US10961198, Compound 5.27 | (1r,4r)-4-Hydroxy-N-(3...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488628(US10961198, Compound 5.25 | cis-N-(3-(1-Cyclopropy...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488627(US10961198, Compound 5.24 | N-(3-(1-Cyclopropyl-1H...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488626(US10961198, Compound 5.23 | trans-N-((trans-4-(6-C...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488622(US10961198, Compound 5.19 | trans-4-Hydroxy-N-(4-(...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488620(US10961198, Compound 5.17 | trans-N-(3-(1-Cyclobut...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488636(US10961198, Compound 6.02 | trans-4-Hydroxy-N-(3-(...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488587(US10961198, Compound 3.02 | trans-4-Hydroxy-N-(3-(...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488585(US10961198, Compound 3 | trans-N-(3-(1-Cyclopropyl...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488584(US10961198, Compound 2.09 | trans-4-Hydroxy-N-(4-(...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488583(US10961198, Compound 2.08 | trans-N-(4-(1-Cyclopro...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488582(US10961198, Compound 2.07 | trans-N-(4-(1-Cyclopro...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488581(US10961198, Compound 2.06 | trans-4-Hydroxy-N-((tr...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488580(US10961198, Compound 2.05 | trans-N-(3-(1-(2,2-Dif...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488579(US10961198, Compound 2.04 | trans-N-((trans-4-(3-C...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488578(US10961198, Compound 2.03 | trans-N-((trans-4-(3-C...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488577(US10961198, Compound 2.02 | trans-N-(3-(1-Ethyl-1H...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488576(US10961198, Compound 2.01 | trans-4-Hydroxy-N-((tr...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488575(US10961198, Compound 2 | trans-N-((trans-4-(3-Cyan...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488603(US10961198, Compound 5 | trans-N-(3-(1-Cyclopropyl...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488602(US10961198, Compound 4.03 | trans-N-(3-((1H-Pyrazo...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488601(US10961198, Compound 4.02 | trans-4-Hydroxy-N-((tr...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488600(US10961198, Compound 4.01 | trans-N-(3-((1H-Pyrazo...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488599(US10961198, Compound 4 | trans-4-Hydroxy-N-((trans...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488598(US10961198, Compound 3.13 | trans-N-(3-(1-(sec-But...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488597(US10961198, Compound 3.12 | trans-N-(3-(1-(2-Fluor...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488596(US10961198, Compound 3.11 | trans-N-(3-(1-(Difluor...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488595(US10961198, Compound 3.10 | trans-4-Hydroxy-N-((tr...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488594(US10961198, Compound 3.09 | trans-4-Hydroxy-N-((tr...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488593(US10961198, Compound 3.08 | trans-N-(3-(1-Cyclobut...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488592(US10961198, Compound 3.07 | trans-4-Hydroxy-N-((tr...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488589(US10961198, Compound 3.04 | trans-4-Hydroxy-N-((tr...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488588(US10961198, Compound 3.03 | trans-4-Hydroxy-N-(3-(...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488618(US10961198, Compound 5.15 | trans-N-(3-(1-(tert-Bu...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488617(US10961198, Compound 5.14 | trans-N-((trans-4-(3-C...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488616(US10961198, Compound 5.13 | trans-N-((trans-4-(3-C...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488615(US10961198, Compound 5.12 | trans-N-(3-(1-Cyclopro...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488614(US10961198, Compound 5.11 | trans-4-Hydroxy-N-(4-(...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488613(US10961198, Compound 5.10 | trans-N-((trans-4-(5-c...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488611(US10961198, Compound 5.08 | trans-N-(3-(1-(tert-Bu...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488610(US10961198, Compound 5.07 | trans-4-Hydroxy-N-(3-(...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488609(US10961198, Compound 5.06 | trans-N-((trans-4-(Ben...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488608(US10961198, Compound 5.05 | trans-N-((trans-4-(6-C...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488607(US10961198, Compound 5.04 | trans-N-(3-(1-cyclopro...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488606(US10961198, Compound 5.03 | trans-N-((trans-4-(3-C...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

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