Compile Data Set for Download or QSAR
Report error Found 80 Enz. Inhib. hit(s) with all data for entry = 9909
TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498166BDBM498166(US11013745, Compound SL-E14)
Affinity DataIC50: 1.70nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498165BDBM498165(US11013745, Compound SL-ZYE-183)
Affinity DataIC50: 2.20nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498157BDBM498157(US11013745, Compound SL-ZYE-147)
Affinity DataIC50: 2.5nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498156BDBM498156(US11013745, Compound SL-ZYE-146)
Affinity DataIC50: 2.90nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498150BDBM498150(US11013745, Compound SL-ZYE-34)
Affinity DataIC50: 3.20nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498164BDBM498164(US11013745, Compound SL-E13)
Affinity DataIC50: 3.30nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498129BDBM498129(US11013745, Compound E-Y45)
Affinity DataIC50: 3.40nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498155BDBM498155(US11013745, Compound SL-ZYE-144)
Affinity DataIC50: 3.5nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498170BDBM498170(US11013745, Compound SL-ZYE-120)
Affinity DataIC50: 3.60nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498162BDBM498162(US11013745, Compound SL-E24)
Affinity DataIC50: 3.90nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498136BDBM498136(US11013745, Compound E-Y54-H | US11013745, Compoun...)
Affinity DataIC50: 4.10nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498171BDBM498171(US11013745, Compound SL-ZYE-121)
Affinity DataIC50: 4.20nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498140BDBM498140(US11013745, Compound SL-ZYE-09)
Affinity DataIC50: 4.5nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498158BDBM498158(US11013745, Compound SL-ZYE-148)
Affinity DataIC50: 4.70nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498152BDBM498152(US11013745, Compound SL-E23)
Affinity DataIC50: 4.70nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498126BDBM498126(US11013745, Compound E-Y42)
Affinity DataIC50: 4.80nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498136BDBM498136(US11013745, Compound E-Y54-H | US11013745, Compoun...)
Affinity DataIC50: 5nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498160BDBM498160(US11013745, Compound SL-ZYE-162)
Affinity DataIC50: 5.20nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498134BDBM498134(US11013745, Compound E-Y50)
Affinity DataIC50: 5.30nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498132BDBM498132(US11013745, Compound E-Y48)
Affinity DataIC50: 5.40nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498096BDBM498096(US11013745, Compound E-Y15)
Affinity DataIC50: 5.60nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498098BDBM498098(US11013745, Compound E-Y17)
Affinity DataIC50: 6.10nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498133BDBM498133(US11013745, Compound E-Y49)
Affinity DataIC50: 6.60nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498137BDBM498137(US11013745, Compound SL-ZYE-07)
Affinity DataIC50: 7.30nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498169BDBM498169(US11013745, Compound SL-ZYE-197)
Affinity DataIC50: 7.80nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498084BDBM498084(US11013745, Compound E-Y2)
Affinity DataIC50: 8nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498148BDBM498148(US11013745, Compound SL-ZYE-24)
Affinity DataIC50: 8.30nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498163BDBM498163(US11013745, Compound SL-E26)
Affinity DataIC50: 8.40nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498127BDBM498127(US11013745, Compound E-Y43)
Affinity DataIC50: 8.5nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498161BDBM498161(US11013745, Compound SL-ZYE-145)
Affinity DataIC50: 8.90nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498101BDBM498101(US11013745, Compound E-Y19)
Affinity DataIC50: 9.30nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498146BDBM498146(US11013745, Compound E-Y13-H)
Affinity DataIC50: 10.7nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498138BDBM498138(US11013745, Compound SL-ZYE-08)
Affinity DataIC50: 11.9nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498131BDBM498131(US11013745, Compound E-Y47)
Affinity DataIC50: 13nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498168BDBM498168(US11013745, Compound SL-ZYE-196)
Affinity DataIC50: 14.1nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498153BDBM498153(US11013745, Compound SL-E25)
Affinity DataIC50: 15nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498124BDBM498124(US11013745, Compound E-Y40)
Affinity DataIC50: 16.1nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498097BDBM498097(US11013745, Compound E-Y16)
Affinity DataIC50: 17.7nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498141BDBM498141(US11013745, Compound SL-ZYE-11)
Affinity DataIC50: 17.9nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498083BDBM498083(US11013745, Compound E-Y1)
Affinity DataIC50: 18nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498093BDBM498093(US11013745, Compound E-Y13)
Affinity DataIC50: 19nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498125BDBM498125(US11013745, Compound E-Y41)
Affinity DataIC50: 20nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498100BDBM498100(US11013745, Compound E-Y18)
Affinity DataIC50: 21nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498167BDBM498167(US11013745, Compound SL-ZYE-195)
Affinity DataIC50: 22.3nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498149BDBM498149(US11013745, Compound SL-ZYE-28)
Affinity DataIC50: 22.5nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498154BDBM498154(US11013745, Compound SL-ZYE-119)
Affinity DataIC50: 23.3nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498120BDBM498120(US11013745, Compound E-Y37)
Affinity DataIC50: 32.8nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498086BDBM498086(US11013745, Compound E-Y3)
Affinity DataIC50: 37nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498159BDBM498159(US11013745, Compound SL-ZYE-161)
Affinity DataIC50: 40.8nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 498147BDBM498147(US11013745, Compound SL-ZYE-23)
Affinity DataIC50: 47.6nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

Displayed 1 to 50 (of 80 total ) | Next | Last >>
Jump to: