Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 9930
TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500309BDBM500309(US11021475, Example 147)
Affinity DataEC50:  0.877nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500296BDBM500296(US11021475, Example 84)
Affinity DataEC50:  1.28nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500301BDBM500301(US11021475, Example 108)
Affinity DataEC50:  1.46nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500300BDBM500300(US11021475, Example 102)
Affinity DataEC50:  1.59nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500289BDBM500289(US11021475, Example 76 | US11021475, Example 61)
Affinity DataEC50:  1.66nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500308BDBM500308(US11021475, Example 146)
Affinity DataEC50:  1.70nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500299BDBM500299(US11021475, Example 94)
Affinity DataEC50:  1.72nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500303BDBM500303(US11021475, Example 114)
Affinity DataEC50:  1.89nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500302BDBM500302(US11021475, Example 112)
Affinity DataEC50:  1.94nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500298BDBM500298(US11021475, Example 87)
Affinity DataEC50:  2.02nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500318BDBM500318(US11021475, Example 188)
Affinity DataEC50:  5.10nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500288BDBM500288(US11021475, Example 67 | US11021475, Example 52 | ...)
Affinity DataEC50:  5.13nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500293BDBM500293(US11021475, Example 73)
Affinity DataEC50:  5.21nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500292BDBM500292(US11021475, Example 70)
Affinity DataEC50:  5.22nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500305BDBM500305(US11021475, Example 134)
Affinity DataEC50:  5.64nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500316BDBM500316(US11021475, Example 183)
Affinity DataEC50:  5.72nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500289BDBM500289(US11021475, Example 76 | US11021475, Example 61)
Affinity DataEC50:  6.17nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500294BDBM500294(US11021475, Example 75)
Affinity DataEC50:  6.18nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500314BDBM500314(US11021475, Example 176)
Affinity DataEC50:  6.35nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500288BDBM500288(US11021475, Example 67 | US11021475, Example 52 | ...)
Affinity DataEC50:  6.53nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500286BDBM500286(US11021475, Example 16)
Affinity DataEC50:  6.57nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500307BDBM500307(US11021475, Example 142)
Affinity DataEC50:  6.95nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500315BDBM500315(US11021475, Example 181)
Affinity DataEC50:  6.97nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500312BDBM500312(US11021475, Example 155)
Affinity DataEC50:  7.13nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500287BDBM500287(US11021475, Example 51)
Affinity DataEC50:  7.19nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500310BDBM500310(US11021475, Example 151)
Affinity DataEC50:  7.22nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500297BDBM500297(US11021475, Example 85)
Affinity DataEC50:  7.36nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500317BDBM500317(US11021475, Example 186)
Affinity DataEC50:  60nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500313BDBM500313(US11021475, Example 160)
Affinity DataEC50:  70nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500291BDBM500291(US11021475, Example 69)
Affinity DataEC50:  70nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500306BDBM500306(US11021475, Example 140)
Affinity DataEC50:  70nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500319BDBM500319(US11021475, Example 194)
Affinity DataEC50:  80nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500311BDBM500311(US11021475, Example 154)
Affinity DataEC50:  90nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500285BDBM500285(US11021475, Example 10)
Affinity DataEC50:  100nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500304BDBM500304(US11021475, Example 125)
Affinity DataEC50:  110nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500283BDBM500283(US11021475, Example 4)
Affinity DataEC50:  130nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 500284BDBM500284(US11021475, Example 5)
Affinity DataEC50:  410nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent