Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 9970
TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504302BDBM504302(3α,7α,11β,23-tetrahydroxy-6α-e...)
Affinity DataEC50:  7.5nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504302BDBM504302(3α,7α,11β,23-tetrahydroxy-6α-e...)
Affinity DataEC50:  7.5nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504302BDBM504302(3α,7α,11β,23-tetrahydroxy-6α-e...)
Affinity DataEC50:  7.5nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504304BDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  15nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504304BDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  15nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504304BDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  15nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504311BDBM504311(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  29nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504311BDBM504311(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  29nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504306BDBM504306(US11034717, Compound B)
Affinity DataEC50:  30nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504310BDBM504310(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  42nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504310BDBM504310(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  42nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Mouse)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504304BDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  120nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Rat)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504302BDBM504302(3α,7α,11β,23-tetrahydroxy-6α-e...)
Affinity DataEC50:  130nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Rat)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504304BDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  140nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504309BDBM504309(US11034717, Compound L1)
Affinity DataEC50:  150nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504309BDBM504309(US11034717, Compound L1)
Affinity DataEC50:  150nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504305BDBM504305(US11034717, Compound A)
Affinity DataEC50:  200nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Rat)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504311BDBM504311(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  200nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Mouse)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504311BDBM504311(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  210nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504301BDBM504301(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  230nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Rat)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504310BDBM504310(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  240nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Mouse)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504302BDBM504302(3α,7α,11β,23-tetrahydroxy-6α-e...)
Affinity DataEC50:  250nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504303BDBM504303(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  264nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Mouse)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504310BDBM504310(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  270nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504300BDBM504300(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  680nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetFMR1 autosomal homolog 1(Dog)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504311BDBM504311(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  700nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetFMR1 autosomal homolog 1(Dog)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504304BDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  730nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetFMR1 autosomal homolog 1(Dog)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504310BDBM504310(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  800nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetFMR1 autosomal homolog 1(Dog)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504302BDBM504302(3α,7α,11β,23-tetrahydroxy-6α-e...)
Affinity DataEC50:  900nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Mouse)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504309BDBM504309(US11034717, Compound L1)
Affinity DataEC50:  990nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Rat)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504309BDBM504309(US11034717, Compound L1)
Affinity DataEC50:  1.00E+3nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetFMR1 autosomal homolog 1(Dog)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504309BDBM504309(US11034717, Compound L1)
Affinity DataEC50:  4.00E+3nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 504307BDBM504307(US11034717, Compound C)
Affinity DataEC50:  1.75E+5nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent