Compile Data Set for Download or QSAR
Report error Found 149 Enz. Inhib. hit(s) with all data for entry = 9997
TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506733BDBM506733(US11046649, Ex. 111 | 4-(((1R,3s,5S,6r)-6-(1-(5- c...)
Affinity DataIC50: 0.630nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506769BDBM506769(N-(5-cyanopyridin-2-yl)-2- ((1R,3s,5S,6r)-3-((6- f...)
Affinity DataIC50: 0.660nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506768BDBM506768(N-(5-cyanopyrazin-2-yl)-2- ((1R,3s,5S,6r)-3-((6- f...)
Affinity DataIC50: 0.690nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506767BDBM506767(2-((1R,3s,5S,6r)-3-((6- fluoroquinolin-4-yl)oxy)- ...)
Affinity DataIC50: 0.780nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506721BDBM506721(US11046649, Ex. 99 | N-(4-fluorophenyl)-2- ((1R,3s...)
Affinity DataIC50: 0.780nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506758BDBM506758(4-(((1R,3s,5S,6r)-6-(1-(5- chloro-1H-benzo[d]- imi...)
Affinity DataIC50: 0.810nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506730BDBM506730(US11046649, Ex. 108 | N-(4-chlorophenyl)-2- cyclop...)
Affinity DataIC50: 0.820nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506634BDBM506634(US11046649, Ex. 12)
Affinity DataIC50: 0.850nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506736BDBM506736(US11046649, Ex. 114 | N-(4-chlorophenyl)-2- ((1R,3...)
Affinity DataIC50: 0.870nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506731BDBM506731(US11046649, Ex. 109 | 2-cyclopropyl-2- ((1R,3s,5S,...)
Affinity DataIC50: 0.930nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506770BDBM506770(N-(1-(difluoromethyl)-1H- pyrazol-4-yl)-2- ((1R,3s...)
Affinity DataIC50: 0.970nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506737BDBM506737(US11046649, Ex. 115 | 2-((1R,3s,5S,6r)-3-((6- fluo...)
Affinity DataIC50: 0.980nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506766BDBM506766(N-(5-chloropyridin-2-yl)-2- ((1R,3s,5S,6r)-3-((6- ...)
Affinity DataIC50: 1.15nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506693BDBM506693(US11046649, Ex. 71 | 2-((1R,3s,5S,6r)-3-((6- fluor...)
Affinity DataIC50: 1.16nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506759BDBM506759(6-fluoro-4-(((1R,3s,5S,6r)- 6-(1-(5-(trifluorometh...)
Affinity DataIC50: 1.20nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506660BDBM506660(US11046649, Ex. 38 | 4-chloro-N-((R)-cyclo- propyl...)
Affinity DataIC50: 1.37nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506685BDBM506685(US11046649, Ex. 63 | N-(6-cyclopropylpyridin-3- yl...)
Affinity DataIC50: 1.40nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506742BDBM506742(US11046649, Ex. 120 | 2-((1R,3s,5S,6r)-3-((6- fluo...)
Affinity DataIC50: 1.43nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506738BDBM506738(US11046649, Ex. 116 | 2-((1R,3s,5S,6r)-3-((6- fluo...)
Affinity DataIC50: 1.51nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506694BDBM506694(US11046649, Ex. 72 | 2-((1R,3s,5S,6r)-3-((6- fluor...)
Affinity DataIC50: 1.51nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506745BDBM506745(2-cyclopropyl-2- ((1R,3s,5S,6r)-3-((6- fluoroquino...)
Affinity DataIC50: 1.54nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506735BDBM506735(US11046649, Ex. 113 | 2-cyclopropyl-2- ((1R,3s,5S,...)
Affinity DataIC50: 1.56nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506739BDBM506739(US11046649, Ex. 117 | N-(6-cyclopropylpyridin-3- y...)
Affinity DataIC50: 1.57nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506697BDBM506697(US11046649, Ex. 75 | N-(5-cyanopyrazin-2-yl)-2- ((...)
Affinity DataIC50: 1.58nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506743BDBM506743(N-(5-cyanopyridin-2-yl)-2- cyclopropyl-2- ((1R,3s,...)
Affinity DataIC50: 1.67nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506760BDBM506760(4-(((1R,3s,5S,6r)-6-(1-(6- chloro-3H-imidazo[4,5- ...)
Affinity DataIC50: 1.70nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506732BDBM506732(US11046649, Ex. 110 | 2-cyclopropyl-N-(6-cyclo- pr...)
Affinity DataIC50: 1.82nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506657BDBM506657(US11046649, Ex. 35 | 2-((1R,3s,5S,6r)-3-(5,6- difl...)
Affinity DataIC50: 1.92nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506686BDBM506686(US11046649, Ex. 64 | N-(1-(difluoromethyl)-1H- pyr...)
Affinity DataIC50: 2nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506680BDBM506680(US11046649, Ex. 58 | N-(5-cyanopyridin-2-yl)-2- ((...)
Affinity DataIC50: 2nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506747BDBM506747(2-cyclopropyl-2- ((1R,3s,5S,6r)-3-((6- fluoroquino...)
Affinity DataIC50: 2.02nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506658BDBM506658(US11046649, Ex. 36 | N-(4-cyanophenyl)-2- ((1R,3s,...)
Affinity DataIC50: 2.10nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506750BDBM506750(N-(5-cyanopyrazin-2-yl)-2- cyclopropyl-2- ((1R,3s,...)
Affinity DataIC50: 2.14nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506625BDBM506625(US11046649, Ex. 3)
Affinity DataIC50: 2.20nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506683BDBM506683(US11046649, Ex. 61 | 2-((1R,3s,5S,6r)-3-((6- fluor...)
Affinity DataIC50: 2.30nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506679BDBM506679(US11046649, Ex. 57 | N-(5-bromopyrazin-2-yl)-2- ((...)
Affinity DataIC50: 2.40nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506644BDBM506644(N-(5-chloropyridin-2-yl)-2- ((1R,3s,5S,6r)-3-(5,6-...)
Affinity DataIC50: 2.5nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506725BDBM506725(US11046649, Ex. 103 | 2-((1R,3s,5S,6r)-3-((6- fluo...)
Affinity DataIC50: 2.5nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506765BDBM506765(2-((1R,3s,5S,6r)-3-((6- fluoroquinolin-4-yl)- oxy)...)
Affinity DataIC50: 2.77nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506748BDBM506748(2-cyclopropyl-N-(1- (difluoromethyl)-1H- pyrazol-4...)
Affinity DataIC50: 2.85nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506709BDBM506709(US11046649, Ex. 87 | 2-((1R,3s,5S,6r)-3-((6- fluor...)
Affinity DataIC50: 3nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506639BDBM506639(N-(5-cyanopyridin-2-yl)-2- ((1R,3s,5S,6r)-3-(5,6- ...)
Affinity DataIC50: 3.20nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506700BDBM506700(US11046649, Ex. 78 | 2-((1R,3s,5S,6r)-3-((6- fluor...)
Affinity DataIC50: 3.30nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506648BDBM506648(US11046649, Ex. 26 | 2-((1R,3s,5S,6r)-3-(5,6- difl...)
Affinity DataIC50: 3.36nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506659BDBM506659(US11046649, Ex. 37 | 4-chloro-N-((R)-cyclo- propyl...)
Affinity DataIC50: 3.60nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506724BDBM506724(US11046649, Ex. 102 | 2-((1R,3s,5S,6r)-3-((6- fluo...)
Affinity DataIC50: 3.70nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506681BDBM506681(US11046649, Ex. 59 | 2-((1R,3s,5S,6r)-3-((6- fluor...)
Affinity DataIC50: 3.70nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506744BDBM506744(N-(5-chloropyridin-2-yl)-2- cyclopropyl-2- ((1R,3s...)
Affinity DataIC50: 4nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506734BDBM506734(US11046649, Ex. 112 | N-(5-(1H-1,2,4-triazol-1- yl...)
Affinity DataIC50: 4.20nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 506638BDBM506638(N-(4-chlorophenyl)-2- ((1R,3s,5S,6r)-3-(6-cyano- 1...)
Affinity DataIC50: 4.40nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

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