Compile Data Set for Download or QSAR
Report error Found 414 Enz. Inhib. hit(s) with all data for entry = 10004
TargetVascular endothelial growth factor receptor 2(Human)
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LigandChemical structure of BindingDB Monomer ID 50026612BDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKi:  3.80nMAssay Description:The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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PDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
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LigandChemical structure of BindingDB Monomer ID 507109BDBM507109(US11046672, Example 58)
Affinity DataKi:  3.86nMAssay Description:The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor alpha(Human)
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LigandChemical structure of BindingDB Monomer ID 507056BDBM507056((Z)-Methyl 3-(((4-((2-(dimethylamino)ethoxy)carbam...)
Affinity DataKi:  4.57nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507078BDBM507078(US11046672, Example 27)
Affinity DataKi:  4.77nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507083BDBM507083(US11046672, Example 32)
Affinity DataKi:  4.92nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetVascular endothelial growth factor receptor 2(Human)
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LigandChemical structure of BindingDB Monomer ID 507111BDBM507111(US11046672, Example 60)
Affinity DataKi:  5.24nMAssay Description:The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetVascular endothelial growth factor receptor 2(Human)
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LigandChemical structure of BindingDB Monomer ID 507108BDBM507108(US11046672, Example 57)
Affinity DataKi:  5.36nMAssay Description:The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507090BDBM507090(US11046672, Example 39)
Affinity DataKi:  5.39nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetVascular endothelial growth factor receptor 2(Human)
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LigandChemical structure of BindingDB Monomer ID 507110BDBM507110(US11046672, Example 59)
Affinity DataKi:  5.43nMAssay Description:The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetVascular endothelial growth factor receptor 2(Human)
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LigandChemical structure of BindingDB Monomer ID 507113BDBM507113(US11046672, Example 62)
Affinity DataKi:  5.74nMAssay Description:The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 50026612BDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKi:  5.90nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507116BDBM507116(US11046672, Example 66)
Affinity DataKi:  6.30nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507082BDBM507082(US11046672, Example 31)
Affinity DataKi:  6.58nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507058BDBM507058((Z)-Methyl 3-(((4-((2-(4-(2-hydroxyethyl)piperazin...)
Affinity DataKi:  6.60nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor alpha(Human)
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LigandChemical structure of BindingDB Monomer ID 507090BDBM507090(US11046672, Example 39)
Affinity DataKi:  6.71nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507056BDBM507056((Z)-Methyl 3-(((4-((2-(dimethylamino)ethoxy)carbam...)
Affinity DataKi:  6.78nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507113BDBM507113(US11046672, Example 62)
Affinity DataKi:  6.78nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507089BDBM507089(US11046672, Example 38)
Affinity DataKi:  6.91nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507093BDBM507093(US11046672, Example 42)
Affinity DataKi:  7.06nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507090BDBM507090(US11046672, Example 39)
Affinity DataKi:  7.06nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507056BDBM507056((Z)-Methyl 3-(((4-((2-(dimethylamino)ethoxy)carbam...)
Affinity DataKi:  7.13nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507107BDBM507107(US11046672, Example 56)
Affinity DataKi:  7.19nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507081BDBM507081(US11046672, Example 30)
Affinity DataKi:  7.32nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507069BDBM507069(US11046672, Example 18)
Affinity DataKi:  7.42nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507080BDBM507080(US11046672, Example 29)
Affinity DataKi:  7.48nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor alpha(Human)
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LigandChemical structure of BindingDB Monomer ID 507073BDBM507073(US11046672, Example 22)
Affinity DataKi:  7.54nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507091BDBM507091(US11046672, Example 40)
Affinity DataKi:  7.66nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507089BDBM507089(US11046672, Example 38)
Affinity DataKi:  7.68nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507079BDBM507079(US11046672, Example 28)
Affinity DataKi:  7.88nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507115BDBM507115(US11046672, Example 65)
Affinity DataKi:  7.90nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507122BDBM507122(US11046672, Example 73)
Affinity DataKi:  7.90nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507122BDBM507122(US11046672, Example 73)
Affinity DataKi:  7.90nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 50026612BDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKi:  8nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507073BDBM507073(US11046672, Example 22)
Affinity DataKi:  8.14nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507057BDBM507057((Z)-Methyl 5-methyl-3-(((4-((2-(4-methylpiperazin-...)
Affinity DataKi:  8.31nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507054BDBM507054((Z)-Methyl 3-(((4-((2-(dimethylamino)ethoxy)carbam...)
Affinity DataKi:  8.32nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetPlatelet-derived growth factor receptor alpha(Human)
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LigandChemical structure of BindingDB Monomer ID 50026612BDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKi:  8.40nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507087BDBM507087(US11046672, Example 36)
Affinity DataKi:  8.46nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507084BDBM507084(US11046672, Example 33)
Affinity DataKi:  8.47nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507077BDBM507077(US11046672, Example 26)
Affinity DataKi:  8.61nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507054BDBM507054((Z)-Methyl 3-(((4-((2-(dimethylamino)ethoxy)carbam...)
Affinity DataKi:  8.65nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
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TargetPlatelet-derived growth factor receptor alpha(Human)
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LigandChemical structure of BindingDB Monomer ID 507082BDBM507082(US11046672, Example 31)
Affinity DataKi:  8.74nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetPlatelet-derived growth factor receptor alpha(Human)
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LigandChemical structure of BindingDB Monomer ID 507057BDBM507057((Z)-Methyl 5-methyl-3-(((4-((2-(4-methylpiperazin-...)
Affinity DataKi:  8.80nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetPlatelet-derived growth factor receptor alpha(Human)
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LigandChemical structure of BindingDB Monomer ID 507058BDBM507058((Z)-Methyl 3-(((4-((2-(4-(2-hydroxyethyl)piperazin...)
Affinity DataKi:  8.80nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507058BDBM507058((Z)-Methyl 3-(((4-((2-(4-(2-hydroxyethyl)piperazin...)
Affinity DataKi:  8.85nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507109BDBM507109(US11046672, Example 58)
Affinity DataKi:  8.87nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
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LigandChemical structure of BindingDB Monomer ID 507109BDBM507109(US11046672, Example 58)
Affinity DataKi:  8.96nMAssay Description:The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
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TargetPlatelet-derived growth factor receptor alpha(Human)
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LigandChemical structure of BindingDB Monomer ID 507078BDBM507078(US11046672, Example 27)
Affinity DataKi:  9.11nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507110BDBM507110(US11046672, Example 59)
Affinity DataKi:  9.19nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
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TargetPlatelet-derived growth factor receptor beta(Human)
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LigandChemical structure of BindingDB Monomer ID 507101BDBM507101(US11046672, Example 50)
Affinity DataKi:  9.24nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
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