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Found 33 Enz. Inhib. hit(s) with all data for entry = 10007
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507637(1-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[[4-hydroxy...)
Affinity DataIC50:  19.6nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507626(3-[[4-hydroxy-1-[(3R,4R)-3-phenylpiperidine-4-carb...)
Affinity DataIC50:  28.7nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507620(3-[[4-hydroxy-1-[(3R,4R)-3-phenylpiperidine-4-carb...)
Affinity DataIC50:  31.6nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507625(7-(4-fluorophenyl)-3-[[4-hydroxy-1-[(3R,4R)-3-phen...)
Affinity DataIC50:  37.7nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507635(7-(4-fluoro-3-methoxy-phenyl)-3-[[4-hydroxy-1-[(3R...)
Affinity DataIC50:  39.3nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507630(7-(4-chlorophenyl)-3-[[4-hydroxy-1-[(3R,4R)-3-phen...)
Affinity DataIC50:  41.2nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507627(3-[[4-hydroxy-1-[(3R,4R)-3-phenylpiperidine-4-carb...)
Affinity DataIC50:  48.6nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507634(7-(4-chlorophenyl)-3-[[4-hydroxy-1-[(3R,4R)-1-meth...)
Affinity DataIC50:  48.6nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507616(US11046681, Example 40 | tert-butyl (3R,4R)-4-[4-h...)
Affinity DataIC50:  49.9nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507632(3-[[4-hydroxy-1-[(3R,4R)-1-methyl-3-phenyl-piperid...)
Affinity DataIC50:  52.4nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507621(5-[[4-hydroxy-1-[(3R,4R)-3-phenylpiperidine-4-carb...)
Affinity DataIC50:  52.9nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507629(7-(3-chlorophenyl)-3-[[4-hydroxy-1-[(3R,4R)-3-phen...)
Affinity DataIC50:  56.7nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507617(US11046681, Example 44 | tert-butyl (3R,4R)-4-[4-h...)
Affinity DataIC50:  61.5nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507633(7-(3-chlorophenyl)-3-[[4-hydroxy-1-[(3R,4R)-1-meth...)
Affinity DataIC50:  64.8nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507619(US11046681, Example 64 | tert-butyl (3R,4R)-4-[4-[...)
Affinity DataIC50:  68.7nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507618(US11046681, Example 57 | tert-butyl (3R,4R)-4-[4-[...)
Affinity DataIC50:  70.2nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507644(3-[[1-[(3R,4R)-1-acetyl-3-phenyl-piperidine-4-carb...)
Affinity DataIC50:  74.2nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507628(7-(4-fluorophenyl)-3-[[4-hydroxy-1-[(3R,4R)-1-meth...)
Affinity DataIC50:  74.8nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507645(3-[[1-[(3R,4R)-1-(2,2-dimethylpropanoyl)-3-phenyl-...)
Affinity DataIC50:  83nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507642(3-[[1-[(3R,4R)-1-acetyl-3-phenyl-piperidine-4-carb...)
Affinity DataIC50:  88.4nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
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US Patent
LigandPNGBDBM507646(3-[[1-[(3R,4R)-1-(3,3-dimethylbutanoyl)-3-phenyl-p...)
Affinity DataIC50:  88.5nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507643(3-[[1-[(3R,4R)-1-acetyl-3-phenyl-piperidine-4-carb...)
Affinity DataIC50:  89nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507641(3-[[1-[(3R,4R)-1-acetyl-3-phenyl-piperidine-4-carb...)
Affinity DataIC50:  96.1nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507638(3-[[1-[(3R,4R)-1-acetyl-3-phenyl-piperidine-4-carb...)
Affinity DataIC50:  102nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507640(3-[[4-hydroxy-1-[(3R,4R)-1-(2-methylpropanoyl)-3-p...)
Affinity DataIC50:  103nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507636(3-[[4-hydroxy-1-[(3R,4R)-1-isobutyl-3-phenyl-piper...)
Affinity DataIC50:  108nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507161(US11046681, Example 2 | tert-butyl (3R,4R)-4-[4-hy...)
Affinity DataIC50:  128nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507624(3-[[4-hydroxy-1-[(3R,4R)-1-methyl-3-phenyl-piperid...)
Affinity DataIC50:  140nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507450(US11046681, Example 15 | tert-butyl (3R,4R)-4-[4-h...)
Affinity DataIC50:  274nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507622(3-[[4-hydroxy-1-[(3R,4R)-3-phenylpiperidine-4-carb...)
Affinity DataIC50:  394nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507631(3-[[1-[(3R,4R)-1-acetyl-3-phenyl-piperidine-4-carb...)
Affinity DataIC50:  406nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507639(5-[[1-[(3R,4R)-1,1-dimethyl-3-phenyl-piperidin-1-i...)
Affinity DataIC50:  860nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM507623(3-[[4-hydroxy-1-[(3R,4R)-3-phenyl-1-(2,2,2-trifluo...)
Affinity DataIC50:  1.20E+3nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent