Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 10106
TargetHIV-1 protease(Human immunodeficiency virus)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 514108BDBM514108(US11052087, Compound 1)
Affinity DataEC50:  4.62nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 514120BDBM514120(US11052087, Compound 14)
Affinity DataEC50:  6.54nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 514118BDBM514118(US11052087, Compound 9)
Affinity DataEC50:  20.6nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 514109BDBM514109(US11052087, Compound 2)
Affinity DataEC50:  56.6nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 514117BDBM514117(US11052087, Compound 8)
Affinity DataEC50:  102nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 514116BDBM514116(US11052087, Compound 7)
Affinity DataEC50:  247nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 514115BDBM514115(US11052087, Compound 6)
Affinity DataEC50:  278nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 514111BDBM514111(US11052087, Compound 3)
Affinity DataEC50:  603nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 514114BDBM514114(US11052087, Compound 5)
Affinity DataEC50:  1.14E+3nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 514113BDBM514113(US11052087, Compound 4)
Affinity DataEC50:  5.71E+3nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent