Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 10058
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313174(US10166249, Example 689 | US10709719, Example 690 ...)
Affinity DataIC50:  1.70nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313176(US10166249, Example 692 | US11058696, Example 692 ...)
Affinity DataIC50:  2.30nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313175(US10166249, Example 690 | US11058696, Example 690 ...)
Affinity DataIC50:  3nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313177(US10166249, Example 693 | US10709719, Example 694 ...)
Affinity DataIC50:  5.20nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313181(US10166249, Example 701 | US10709719, Example 702 ...)
Affinity DataIC50:  48.7nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM511434(US11058696, Example 698)
Affinity DataIC50:  69.4nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313178(US10166249, Example 695 | US10709719, Example 696 ...)
Affinity DataIC50:  119nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313182(US10166249, Example 702 | US11058696, Example 702 ...)
Affinity DataIC50:  151nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM258471(US10166249, Example 699 | US10709719, Example 699 ...)
Affinity DataIC50:  183nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313178(US10166249, Example 695 | US10709719, Example 696 ...)
Affinity DataEC50:  49nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313178(US10166249, Example 695 | US10709719, Example 696 ...)
Affinity DataEC50: >625nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313184(US10166249, Example 696 | US11058696, Example 696)
Affinity DataEC50:  1.20nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313184(US10166249, Example 696 | US11058696, Example 696)
Affinity DataEC50: >1.00E+3nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313179(US10166249, Example 697 | US10166249, Example 698 ...)
Affinity DataEC50:  0.600nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313179(US10166249, Example 697 | US10166249, Example 698 ...)
Affinity DataEC50: >1.00E+3nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM511434(US11058696, Example 698)
Affinity DataEC50:  8.90nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM511434(US11058696, Example 698)
Affinity DataEC50: >625nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM258471(US10166249, Example 699 | US10709719, Example 699 ...)
Affinity DataEC50:  82.6nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM258471(US10166249, Example 699 | US10709719, Example 699 ...)
Affinity DataEC50: >625nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313181(US10166249, Example 701 | US10709719, Example 702 ...)
Affinity DataEC50:  133nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313181(US10166249, Example 701 | US10709719, Example 702 ...)
Affinity DataEC50: >1.25E+3nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313182(US10166249, Example 702 | US11058696, Example 702 ...)
Affinity DataEC50:  120nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313182(US10166249, Example 702 | US11058696, Example 702 ...)
Affinity DataEC50: >625nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313183(US10166249, Example 694 | US11058696, Example 694)
Affinity DataEC50: >1.25E+3nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313183(US10166249, Example 694 | US11058696, Example 694)
Affinity DataEC50:  38.6nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313177(US10166249, Example 693 | US10709719, Example 694 ...)
Affinity DataEC50: >4.16E+3nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313177(US10166249, Example 693 | US10709719, Example 694 ...)
Affinity DataEC50:  19.2nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313176(US10166249, Example 692 | US11058696, Example 692 ...)
Affinity DataEC50: >625nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313176(US10166249, Example 692 | US11058696, Example 692 ...)
Affinity DataEC50:  4.40nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313175(US10166249, Example 690 | US11058696, Example 690 ...)
Affinity DataEC50: >625nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313174(US10166249, Example 689 | US10709719, Example 690 ...)
Affinity DataEC50:  5.70nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313174(US10166249, Example 689 | US10709719, Example 690 ...)
Affinity DataEC50: >2.00E+3nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313175(US10166249, Example 690 | US11058696, Example 690 ...)
Affinity DataEC50:  21.4nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent