Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 10105
TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514094BDBM514094(US11059858, Example 48)
Affinity DataIC50: 0.300nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514076BDBM514076(US11059858, Example 33)
Affinity DataIC50: 0.300nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514085BDBM514085(US11059858, Example 42)
Affinity DataIC50: 0.300nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514090BDBM514090(US11059858, Example 44)
Affinity DataIC50: 0.400nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514091BDBM514091(US11059858, Example 45)
Affinity DataIC50: 0.400nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514056BDBM514056(US11059858, Example 15)
Affinity DataIC50: 0.400nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514098BDBM514098(US11059858, Example 52 | N-[(2S)-3-(3-Chlorophenyl...)
Affinity DataIC50: 0.400nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514104BDBM514104(US11059858, Example 58)
Affinity DataIC50: 0.400nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514086BDBM514086(US11059858, Example 43)
Affinity DataIC50: 0.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514057BDBM514057(US11059858, Example 16)
Affinity DataIC50: 0.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514075BDBM514075(US11059858, Example 32)
Affinity DataIC50: 0.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514058BDBM514058(US11059858, Example 17)
Affinity DataIC50: 0.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514077BDBM514077(US11059858, Example 34)
Affinity DataIC50: 0.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514078BDBM514078(US11059858, Example 35)
Affinity DataIC50: 0.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514061BDBM514061(US11059858, Example 20)
Affinity DataIC50: 0.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514079BDBM514079(US11059858, Example 36)
Affinity DataIC50: 0.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514102BDBM514102(US11059858, Example 56)
Affinity DataIC50: 0.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514059BDBM514059(US11059858, Example 18)
Affinity DataIC50: 0.600nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514099BDBM514099(US11059858, Example 53 | 3,5-Dichloro-N-[(2S)-3-(3...)
Affinity DataIC50: 0.600nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514063BDBM514063(US11059858, Example 22)
Affinity DataIC50: 0.600nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514101BDBM514101(US11059858, Example 55)
Affinity DataIC50: 0.600nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514103BDBM514103(US11059858, Example 57)
Affinity DataIC50: 0.600nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514084BDBM514084(US11059858, Example 41 | (4S)-4-[[(2S)-2-[[(2S)-3-...)
Affinity DataIC50: 0.600nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514093BDBM514093(US11059858, Example 47)
Affinity DataIC50: 0.700nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514097BDBM514097(US11059858, Example 51)
Affinity DataIC50: 0.800nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514046BDBM514046(US11059858, Example 6)
Affinity DataIC50: 0.800nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514092BDBM514092(US11059858, Example 46)
Affinity DataIC50: 0.900nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514096BDBM514096(US11059858, Example 50)
Affinity DataIC50: 0.900nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514080BDBM514080(US11059858, Example 37 | tert-Butyl 2-[4-[[(2S)-3-...)
Affinity DataIC50: 0.900nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514047BDBM514047(US11059858, Example 7)
Affinity DataIC50: 1.10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514055BDBM514055(US11059858, Example 14)
Affinity DataIC50: 1.30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514106BDBM514106(US11059858, Example 60)
Affinity DataIC50: 1.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514044BDBM514044(US11059858, Example 5 | N-[(2S)-3-(3,4-Dichlorophe...)
Affinity DataIC50: 1.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514095BDBM514095(US11059858, Example 49)
Affinity DataIC50: 1.60nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514100BDBM514100(US11059858, Example 54)
Affinity DataIC50: 1.70nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514105BDBM514105(US11059858, Example 59)
Affinity DataIC50: 2nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514049BDBM514049(US11059858, Example 9)
Affinity DataIC50: 2.10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514070BDBM514070(US11059858, Example 29 | 2,5-Dichloro-N-[(2S)-1-[[...)
Affinity DataIC50: 2.30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514041BDBM514041(US11059858, Example 2 | N-[(2S)-3-(3-Chlorophenyl)...)
Affinity DataIC50: 2.30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514051BDBM514051(US11059858, Example 11)
Affinity DataIC50: 2.40nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514107BDBM514107(US11059858, Example 61 | (4S)-4-[[(2S)-2-[[(2S)-2-...)
Affinity DataIC50: 2.60nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514048BDBM514048(US11059858, Example 8)
Affinity DataIC50: 3nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514071BDBM514071(US11059858, Example 30 | 3-Chloro-N-[(2S)-1-[[(1S)...)
Affinity DataIC50: 4.30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514067BDBM514067(US11059858, Example 26 | N-[(2S)-1-[[(1S)-2-[[(3S)...)
Affinity DataIC50: 6.40nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514054BDBM514054(US11059858, Example 13)
Affinity DataIC50: 6.80nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514050BDBM514050(US11059858, Example 10)
Affinity DataIC50: 6.80nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514039BDBM514039(US11059858, Example 1 | N-[(2S)-3-(3-chlorophenyl)...)
Affinity DataIC50: 8.30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514042BDBM514042(US11059858, Example 3 | N-[(2S)-3-(3-Chlorophenyl)...)
Affinity DataIC50: 8.60nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514073BDBM514073(US11059858, Example 31)
Affinity DataIC50: 9nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 514043BDBM514043(US11059858, Example 4 | N-[(2S)-3-(3-hlorophenyl)-...)
Affinity DataIC50: 9.30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

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