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Found 36 Enz. Inhib. hit(s) with all data for entry = 10054
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511066(US11078214, Compound PTX)
Affinity DataIC50:  2nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511063(US11078214, Compound 18)
Affinity DataIC50:  13nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511066(US11078214, Compound PTX)
Affinity DataIC50:  41nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511062(US11078214, Compound 17)
Affinity DataIC50:  66nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511055(US11078214, Compound 11 | US11078214, Compound A)
Affinity DataIC50:  80nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511065(US11078214, Compound TMP)
Affinity DataIC50:  92nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511058(US11078214, Compound 13)
Affinity DataIC50:  96nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511052(US11078214, Compound 8)
Affinity DataIC50:  112nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511047(US11078214, Compound 4)
Affinity DataIC50:  122nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511060(US11078214, Compound 15)
Affinity DataIC50:  123nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511050(US11078214, Compound 6)
Affinity DataIC50:  150nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511059(US11078214, Compound 14)
Affinity DataIC50:  150nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511063(US11078214, Compound 18)
Affinity DataIC50:  153nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511054(US11078214, Compound 10)
Affinity DataIC50:  155nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511049(US11078214, Compound 5)
Affinity DataIC50:  174nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511057(US11078214, Compound 12)
Affinity DataIC50:  194nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511061(US11078214, Compound 16)
Affinity DataIC50:  201nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511051(US11078214, Compound 7)
Affinity DataIC50:  239nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511053(US11078214, Compound 9)
Affinity DataIC50:  275nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511055(US11078214, Compound 11 | US11078214, Compound A)
Affinity DataIC50:  870nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511062(US11078214, Compound 17)
Affinity DataIC50:  903nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511058(US11078214, Compound 13)
Affinity DataIC50:  942nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511051(US11078214, Compound 7)
Affinity DataIC50:  1.10E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511060(US11078214, Compound 15)
Affinity DataIC50:  1.34E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511061(US11078214, Compound 16)
Affinity DataIC50:  1.37E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511047(US11078214, Compound 4)
Affinity DataIC50:  1.53E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511059(US11078214, Compound 14)
Affinity DataIC50:  1.57E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511049(US11078214, Compound 5)
Affinity DataIC50:  1.58E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511053(US11078214, Compound 9)
Affinity DataIC50:  1.81E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511054(US11078214, Compound 10)
Affinity DataIC50:  2.25E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511050(US11078214, Compound 6)
Affinity DataIC50:  2.46E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511055(US11078214, Compound 11 | US11078214, Compound A)
Affinity DataIC50:  3.10E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511052(US11078214, Compound 8)
Affinity DataIC50:  3.19E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511057(US11078214, Compound 12)
Affinity DataIC50:  4.13E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511055(US11078214, Compound 11 | US11078214, Compound A)
Affinity DataIC50:  4.13E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM511065(US11078214, Compound TMP)
Affinity DataIC50:  2.45E+4nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent