Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 10088
TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513499BDBM513499(US11091482, Compound I-45)
Affinity DataEC50:  5.01nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513472BDBM513472(US11091482, Compound I-27)
Affinity DataEC50:  6.31nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513500BDBM513500(US11091482, Compound I-46)
Affinity DataEC50:  6.31nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513502BDBM513502(US11091482, Compound I-48)
Affinity DataEC50:  6.31nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513453BDBM513453(US11091482, Compound I-8)
Affinity DataEC50:  10nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513496BDBM513496(US11091482, Compound I-42)
Affinity DataEC50:  10nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513503BDBM513503(US11091482, Compound I-49)
Affinity DataEC50:  10nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513469BDBM513469(US11091482, Compound I-24)
Affinity DataEC50:  12.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513454BDBM513454(US11091482, Compound I-9)
Affinity DataEC50:  12.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513498BDBM513498(US11091482, Compound I-44)
Affinity DataEC50:  12.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513501BDBM513501(US11091482, Compound I-47)
Affinity DataEC50:  15.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513480BDBM513480(US11091482, Compound I-35)
Affinity DataEC50:  15.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513482BDBM513482(US11091482, Compound I-37)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513451BDBM513451(US11091482, Compound I-6)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513495BDBM513495(US11091482, Compound I-41)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513447BDBM513447(US11091482, Compound I-2)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513504BDBM513504(US11091482, Compound I-51)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513456BDBM513456(US11091482, Compound I-11)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513459BDBM513459(US11091482, Compound I-14)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513479BDBM513479(US11091482, Compound I-34)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513462BDBM513462(US11091482, Compound I-17)
Affinity DataEC50:  31.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513455BDBM513455(US11091482, Compound I-10)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513471BDBM513471(US11091482, Compound I-26)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513512BDBM513512(US11091482, Compound I-59)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513457BDBM513457(US11091482, Compound I-12)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513515BDBM513515(US11091482, Compound I-62)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513460BDBM513460(US11091482, Compound I-15)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513461BDBM513461(US11091482, Compound I-16)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513477BDBM513477(US11091482, Compound I-32)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513449BDBM513449(US11091482, Compound I-4)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513497BDBM513497(US11091482, Compound I-43)
Affinity DataEC50:  50.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513505BDBM513505(US11091482, Compound I-52)
Affinity DataEC50:  50.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513481BDBM513481(US11091482, Compound I-36)
Affinity DataEC50:  50.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513494BDBM513494(US11091482, Compound I-40)
Affinity DataEC50:  63.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513470BDBM513470(US11091482, Compound I-25)
Affinity DataEC50:  63.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513464BDBM513464(US11091482, Compound I-19)
Affinity DataEC50:  63.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513452BDBM513452(US11091482, Compound I-7)
Affinity DataEC50:  79.4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513468BDBM513468(US11091482, Compound I-23)
Affinity DataEC50:  79.4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513514BDBM513514(US11091482, Compound I-61)
Affinity DataEC50:  79.4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513513BDBM513513(US11091482, Compound I-60)
Affinity DataEC50:  100nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513450BDBM513450(US11091482, Compound I-5)
Affinity DataEC50:  126nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513448BDBM513448(US11091482, Compound I-3)
Affinity DataEC50:  126nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513506BDBM513506(US11091482, Compound I-53)
Affinity DataEC50:  126nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513493BDBM513493(US11091482, Compound I-39)
Affinity DataEC50:  158nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513473BDBM513473(US11091482, Compound I-28)
Affinity DataEC50:  200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513458BDBM513458(US11091482, Compound I-13)
Affinity DataEC50:  200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513463BDBM513463(US11091482, Compound I-18)
Affinity DataEC50:  200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513492BDBM513492(US11091482, Compound I-38)
Affinity DataEC50:  251nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513509BDBM513509(US11091482, Compound I-56)
Affinity DataEC50:  251nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 513475BDBM513475(US11091482, Compound I-30)
Affinity DataEC50:  251nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

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