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Found 85 Enz. Inhib. hit(s) with all data for entry = 10151
LigandPNGBDBM517134(5-(cyclohexylmethyl)-6-methyl-1- tetrahydropyran-4...)
Affinity DataIC50:  29nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517136(5-(cyclohexylmethyl)-6-methyl-1- propyl-pyrazolo[3...)
Affinity DataIC50:  31nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517136(5-(cyclohexylmethyl)-6-methyl-1- propyl-pyrazolo[3...)
Affinity DataIC50:  36nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517155(1-isopropyl-5-[(4- methoxyphenyl)methyl]-6-methyl-...)
Affinity DataIC50:  37nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517155(1-isopropyl-5-[(4- methoxyphenyl)methyl]-6-methyl-...)
Affinity DataIC50:  49nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517140(5-[(4-methoxyphenyl)methyl]-6- (oxetan-3-ylmethyl)...)
Affinity DataIC50:  58nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517142(5-[(2-fluorophenyl)methyl]-6-methyl- 1-tetrahydrop...)
Affinity DataIC50:  61nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517133(5-(4-methoxybenzyl)-6-methyl-1- (tetrahydro-2H-pyr...)
Affinity DataIC50:  62nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517143(5-[(4-chlorophenyl)methyl]-6-methyl- 1-tetrahydrop...)
Affinity DataIC50:  65nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517135(5-[(4-methoxyphenyl)methyl]-6- methyl-1-propyl-pyr...)
Affinity DataIC50:  68nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517147(6-methyl-5-(p-tolylmethyl)-1- tetrahydropyran-4-yl...)
Affinity DataIC50:  71nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517135(5-[(4-methoxyphenyl)methyl]-6- methyl-1-propyl-pyr...)
Affinity DataIC50:  72nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517133(5-(4-methoxybenzyl)-6-methyl-1- (tetrahydro-2H-pyr...)
Affinity DataIC50:  74nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517137(6-ethyl-5-[(4-methoxyphenyl)methyl]- 1-tetrahydrop...)
Affinity DataIC50:  80nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517151(5-(4-methoxybenzyl)-6-methyl-1- propyl-1,5-dihydro...)
Affinity DataIC50:  82nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517163(5-[(4-methoxyphenyl)methyl]-6- methyl-1-[(2S,3R)-2...)
Affinity DataIC50:  83nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517166(5-(4-methoxybenzyl)-6-methyl-1-(4- methyltetrahydr...)
Affinity DataIC50:  87nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517149(5-[(6-methoxy-3-pyridyl)methyl]-6- methyl-1-tetrah...)
Affinity DataIC50:  88nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517145(5-[(3-chlorophenyl)methyl]-6-methyl- 1-tetrahydrop...)
Affinity DataIC50:  95nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517134(5-(cyclohexylmethyl)-6-methyl-1- tetrahydropyran-4...)
Affinity DataIC50:  103nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517137(6-ethyl-5-[(4-methoxyphenyl)methyl]- 1-tetrahydrop...)
Affinity DataIC50:  107nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517135(5-[(4-methoxyphenyl)methyl]-6- methyl-1-propyl-pyr...)
Affinity DataIC50:  108nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517136(5-(cyclohexylmethyl)-6-methyl-1- propyl-pyrazolo[3...)
Affinity DataIC50:  111nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517149(5-[(6-methoxy-3-pyridyl)methyl]-6- methyl-1-tetrah...)
Affinity DataIC50:  113nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517166(5-(4-methoxybenzyl)-6-methyl-1-(4- methyltetrahydr...)
Affinity DataIC50:  119nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517132(6-benzyl-5-(cyclohexylmethyl)-1- tetrahydropyran-4...)
Affinity DataIC50:  120nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517143(5-[(4-chlorophenyl)methyl]-6-methyl- 1-tetrahydrop...)
Affinity DataIC50:  127nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517133(5-(4-methoxybenzyl)-6-methyl-1- (tetrahydro-2H-pyr...)
Affinity DataIC50:  132nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517155(1-isopropyl-5-[(4- methoxyphenyl)methyl]-6-methyl-...)
Affinity DataIC50:  134nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517144(5-benzyl-6-methyl-1-tetrahydropyran-4-yl- pyrazolo...)
Affinity DataIC50:  135nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517137(6-ethyl-5-[(4-methoxyphenyl)methyl]- 1-tetrahydrop...)
Affinity DataIC50:  140nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517141(5-[(3-fluorophenyl)methyl]-6-methyl- 1-tetrahydrop...)
Affinity DataIC50:  149nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517148(5-(1,3-benzodioxol-5-ylmethyl)-6- methyl-1-tetrahy...)
Affinity DataIC50:  154nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517140(5-[(4-methoxyphenyl)methyl]-6- (oxetan-3-ylmethyl)...)
Affinity DataIC50:  165nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517149(5-[(6-methoxy-3-pyridyl)methyl]-6- methyl-1-tetrah...)
Affinity DataIC50:  171nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517134(5-(cyclohexylmethyl)-6-methyl-1- tetrahydropyran-4...)
Affinity DataIC50:  172nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517166(5-(4-methoxybenzyl)-6-methyl-1-(4- methyltetrahydr...)
Affinity DataIC50:  174nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517164(5-[(4-methoxyphenyl)methyl]-6- methyl-1-[(2R,3R)-2...)
Affinity DataIC50:  179nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517138(6-(methoxymethyl)-5-[(4- methoxyphenyl)methyl]-1- ...)
Affinity DataIC50:  181nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517149(5-[(6-methoxy-3-pyridyl)methyl]-6- methyl-1-tetrah...)
Affinity DataIC50:  184nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517146(5-[(4-fluorophenyl)methyl]-6-methyl- 1-tetrahydrop...)
Affinity DataIC50:  204nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517163(5-[(4-methoxyphenyl)methyl]-6- methyl-1-[(2S,3R)-2...)
Affinity DataIC50:  206nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517139(6-isopropyl-5-[(4- methoxyphenyl)methyl]-1- tetrah...)
Affinity DataIC50:  211nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517151(5-(4-methoxybenzyl)-6-methyl-1- propyl-1,5-dihydro...)
Affinity DataIC50:  233nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517142(5-[(2-fluorophenyl)methyl]-6-methyl- 1-tetrahydrop...)
Affinity DataIC50:  250nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517159(1-cyclopropyl-5-[(4- methoxyphenyl)methyl]-6-methy...)
Affinity DataIC50:  255nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517146(5-[(4-fluorophenyl)methyl]-6-methyl- 1-tetrahydrop...)
Affinity DataIC50:  258nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517151(5-(4-methoxybenzyl)-6-methyl-1- propyl-1,5-dihydro...)
Affinity DataIC50:  290nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517144(5-benzyl-6-methyl-1-tetrahydropyran-4-yl- pyrazolo...)
Affinity DataIC50:  309nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM517132(6-benzyl-5-(cyclohexylmethyl)-1- tetrahydropyran-4...)
Affinity DataIC50:  320nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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