Found 76 Enz. Inhib. hit(s) with all data for entry = 10157 TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 1.20E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 1.90E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 2.20E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 2.20E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 2.20E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 2.20E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 2.30E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 2.30E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 2.40E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 2.50E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 2.50E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 2.70E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 3.00E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 3.00E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 3.30E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 3.40E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 3.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 3.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 4.20E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 4.40E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 4.40E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 4.50E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 4.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 5.10E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 5.40E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 5.40E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 5.50E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 5.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 5.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 5.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 6.10E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 6.30E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 6.40E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 6.70E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 7.00E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 7.20E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 7.30E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 7.80E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 8.50E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 8.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 9.00E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 9.50E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 9.90E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 1.02E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 1.02E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 1.08E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 1.08E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 1.13E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 1.14E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 1.14E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
