Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 10171
TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518392(5-Chloro-7-methoxy-2-(2-pyrimidin-2-ylpyrimidin-5-...)
Affinity DataIC50: 68nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518371(7-(Cyclopropylmethoxy)-5-fluoro-2-(2-pyrimidin-2-y...)
Affinity DataIC50: 244nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518393(7-Chloro-5-methoxy-2-(2-pyrimidin-2-ylpyrimidin-5-...)
Affinity DataIC50: 251nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518369(7-(2,2-Difluoroethoxy)-5-fluoro-2-(2-pyrimidin-2-y...)
Affinity DataIC50: 255nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518263(5-Fluoro-7-methoxy-2-(5-pyrimidin-2-ylpyrazin-2-yl...)
Affinity DataIC50: 292nMAssay Description:The assay employs real-time qPCR (TaqMan) to directly measure extracellular HBV DNA copy number in the cell supernatant. HepG2.2.15 cells were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518262(5-Fluoro-7-methoxy-1-methyl-2-(2-pyrimidin-2-ylpyr...)
Affinity DataIC50: 315nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518260(5-Fluoro-7-methoxy-2-(2-pyrimidin-2-ylpyrimidin-5-...)
Affinity DataIC50: 355nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518366(N,N-Dimethyl-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,...)
Affinity DataIC50: 406nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518263(5-Fluoro-7-methoxy-2-(5-pyrimidin-2-ylpyrazin-2-yl...)
Affinity DataIC50: 445nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518261(7-Fluoro-5-methoxy-2-(2-pyrimidin-2-ylpyrimidin-5-...)
Affinity DataIC50: 454nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518394(Ethyl-5-fluoro-7-methoxy-2-(2-pyrimidin-2-ylpyrimi...)
Affinity DataIC50: 790nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518297(7-Methoxy-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,4-d...)
Affinity DataIC50: 990nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518383(2-(2-Pyrimidin-2-ylpyrimidin-5-yl)-3,4-dihydro-1H-...)
Affinity DataIC50: 1.19E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518374(6-Cyclopropyl-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3...)
Affinity DataIC50: 1.38E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518385(7-(3-Methoxyazetidin-1-yl)-2-(2-pyrimidin-2-ylpyri...)
Affinity DataIC50: 1.41E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518365(7-Cyclopropyl-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3...)
Affinity DataIC50: 1.69E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518367(7-Methyl-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,4-di...)
Affinity DataIC50: 2.01E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518372(7-Chloro-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,4-di...)
Affinity DataIC50: 2.04E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518373(N,N-Dimethyl-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,...)
Affinity DataIC50: 2.22E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518258(6,7-Dimethoxy-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3...)
Affinity DataIC50: 2.32E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518265(6-Chloro-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,4-di...)
Affinity DataIC50: 2.52E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518387(5-Fluoro-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,4-di...)
Affinity DataIC50: 3.03E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518272(6,7-Dimethoxy-2-[6-(2-pyridyl)-3-pyridyl]-3,4-dihy...)
Affinity DataIC50: 3.12E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518255(2-(2-Pyrimidin-2-ylpyrimidin-5-yl)-3,4-dihydro-1H-...)
Affinity DataIC50: 3.17E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518296(7-Methoxy-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,4-d...)
Affinity DataIC50: 3.70E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518257(7-Fluoro-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,4-di...)
Affinity DataIC50: 3.89E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518368(N-Methyl-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,4-di...)
Affinity DataIC50: 4.64E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518259(6-Methoxy-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,4-d...)
Affinity DataIC50: 5.20E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518288(2-Methoxy-7-(2-pyrimidin-2-ylpyrimidin-5-yl)-6,8-d...)
Affinity DataIC50: 5.77E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518390(5-Cyclopropyl-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3...)
Affinity DataIC50: 6.89E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518389(2-[[5-Fluoro-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,...)
Affinity DataIC50: 8.52E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518370(2-(2-Pyrimidin-2-ylpyrimidin-5-yl)-3,4-dihydro-1H-...)
Affinity DataIC50: 8.64E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518257(7-Fluoro-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,4-di...)
Affinity DataIC50: 2.25E+4nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518391(N,N-Dimethyl-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,...)
Affinity DataIC50: 4.33E+4nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent