Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 10181
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403344BDBM403344(US10329320, Compound 21 | US10329320, Compound 34 ...)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403346BDBM403346(US10329320, Compound 23 | US11124538, Compound 23)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403347BDBM403347(US10329320, Compound 24 | US11124538, Compound 24)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403348BDBM403348(US10329320, Compound 25 | US11124538, Compound 25)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403349BDBM403349(US10329320, Compound 26 | US11124538, Compound 26)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403350BDBM403350(US10329320, Compound 27 | US11124538, Compound 27)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403351BDBM403351(US10329320, Compound 28 | US11124538, Compound 28)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403352BDBM403352(US10329320, Compound 29 | US11124538, Compound 29)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403353BDBM403353(US10329320, Compound 30 | US11124538, Compound 30)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518512BDBM518512(US11124538, Compound 1)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518599BDBM518599(US11124538, Compound 2)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518601BDBM518601(US11124538, Compound 7)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518603BDBM518603(US11124538, Compound 8)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518604BDBM518604(US11124538, Compound 9)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518607BDBM518607(US11124538, Compound 10)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518614BDBM518614(US11124538, Compound 11)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518622BDBM518622(US11124538, Compound 12)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518633BDBM518633(US11124538, Compound 13)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403337BDBM403337(US10329320, Compound 14 | US11124538, Compound 14)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403338BDBM403338(US10329320, Compound 15 | US11124538, Compound 15)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403340BDBM403340(US10329320, Compound 17 | US11124538, Compound 16)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518699BDBM518699(US11124538, Compound 18)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518700BDBM518700(US11124538, Compound 19)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403343BDBM403343(US10329320, Compound 20 | US11124538, Compound 20)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403377BDBM403377(US10329320, Compound 65 | US11124538, Compound 65)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403380BDBM403380(US10329320, Compound 68 | US11124538, Compound 68)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403381BDBM403381(US10329320, Compound 69 | US11124538, Compound 69)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403382BDBM403382(US10329320, Compound 70 | US11124538, Compound 70)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403384BDBM403384(US10329320, Compound 72 | US11124538, Compound 72)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403369BDBM403369(US10329320, Compound 51 | US11124538, Compound 51)
Affinity DataIC50: 10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518719BDBM518719(US11124538, Compound 42)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403378BDBM403378(US10329320, Compound 66 | US11124538, Compound 66)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403379BDBM403379(US10329320, Compound 67 | US11124538, Compound 67)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403359BDBM403359(US10329320, Compound 40 | US10329320, Compound 44 ...)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518723BDBM518723(US11124538, Compound 46)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518724BDBM518724(US11124538, Compound 47)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403383BDBM403383(US10329320, Compound 71 | US11124538, Compound 71)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403374BDBM403374(US10329320, Compound 62 | US11124538, Compound 73)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518712BDBM518712(US11124538, Compound 34)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403370BDBM403370(US10329320, Compound 52 | US11124538, Compound 52)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403339BDBM403339(US10329320, Compound 16 | US11124538, Compound 17)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403374BDBM403374(US10329320, Compound 62 | US11124538, Compound 73)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403360BDBM403360(US10329320, Compound 41 | US11124538, Compound 41)
Affinity DataIC50: 75nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403362BDBM403362(US10329320, Compound 43 | US11124538, Compound 43)
Affinity DataIC50: 75nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403364BDBM403364(US10329320, Compound 45 | US11124538, Compound 45)
Affinity DataIC50: 75nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403361BDBM403361(US10329320, Compound 42 | US10329320, Compound 48 ...)
Affinity DataIC50: 75nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403368BDBM403368(US10329320, Compound 49 | US11124538, Compound 49)
Affinity DataIC50: 75nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403358BDBM403358(US10329320, Compound 38 | US11124538, Compound 38)
Affinity DataIC50: 75nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 518717BDBM518717(US11124538, Compound 40)
Affinity DataIC50: 75nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 403376BDBM403376(US10329320, Compound 64 | US11124538, Compound 64)
Affinity DataIC50: 300nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

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