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Found 66 Enz. Inhib. hit(s) with all data for entry = 10223
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521037(7-(5-bicyclo[2.2.1]hept-2-enylmethyl)-N- [6-(2,4-d...)
Affinity DataIC50:  10nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521012(7-(5-bicyclo[2.2.1]hept-2-enylmethyl)-N- [6-(1,3-d...)
Affinity DataIC50:  10nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521011(7-(3,3-Dimethylbutyl)-N-[6-(2,4-dimethylpyrazol-3-...)
Affinity DataIC50:  89nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521010(7-(3,3-Dimethylbutyl)-N-[6-(1,3-dimethylpyrazol-4-...)
Affinity DataIC50:  94nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521064(7-(5-bicyclo[2,2.1]hept-2-enylmethyl)-2-[6- (1,3-d...)
Affinity DataIC50:  110nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521072(7-(5-bicyclo[2.2.1]hept-2-enylmethyl)-2-[6- (2,4-d...)
Affinity DataIC50:  160nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521055(7-(5-bicyclo[2.2.1]hept-2-enylmethyl)-2-[6- (2-chl...)
Affinity DataIC50:  180nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521099(N-[[7-(5-bicyclo[2.2.1]hept-2- enylmethyl)-7-azasp...)
Affinity DataIC50:  180nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521049(7-(3,3-Dimethylbutyl)-2-[6-(1,3-dimethylpyrazol-4-...)
Affinity DataIC50:  200nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521043(N-[6-(2,4-dimethylpyrazol-3-yl)pyridazin- 3-yl]-7-...)
Affinity DataIC50:  210nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521065(2-[6-(1,3-dimethylpyrazol-4-yl)pyridazin-3- yl]oxy...)
Affinity DataIC50:  210nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521079(N-[[7-(3,3-Dimethylbutyl)-7-azaspiro[3.5]nonan-2-y...)
Affinity DataIC50:  220nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521040(N-[6-(2,4-dimethylpyrazol-3-yl)pyridazin- 3-yl]-7-...)
Affinity DataIC50:  220nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521080(N-[[7-(5-bicyclo[2.2.1]hept-2- enylmethyl)-7-azasp...)
Affinity DataIC50:  240nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521050(7-(3,3-Dimethylbutyl)-2-[6-(2,4-dimethylpyrazol-3-...)
Affinity DataIC50:  240nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521073(2-[6-(2,4-dimethylpyrazol-3-yl)pyridazin-3- yl]oxy...)
Affinity DataIC50:  250nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521101(7-(5-bicyclo[2.2.1]hept-2-enylmethyl)-2- [[6-(2-ch...)
Affinity DataIC50:  250nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521100(2-[[6-(2-(Chloro-5-fluoro-phenyl)pyridazin-3-yl]ox...)
Affinity DataIC50:  300nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521097(N-[[7-(1-adamantylmethyl)-7- azaspiro[3.5]nonan-2-...)
Affinity DataIC50:  300nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521015(N-[6-(1,3-dimetliylpyrazo]-4-yl)pyridazin- 3-yl]-7...)
Affinity DataIC50:  330nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521051(2-[6-(2-Chloro-5-fluoro-phenyl)pyridazin-3-yl]oxy-...)
Affinity DataIC50:  330nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521081(6-(2-chloro-5-fluoro-phenyl)-N-[[7- (3,3-dimethylb...)
Affinity DataIC50:  470nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521061(2-[6-(2-chloro-5-fluoro-phenyl)pyridazin-3- yl]oxy...)
Affinity DataIC50:  530nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521057(2-[6-(2-chloro-5-fluoro-phenyl)pyridazin-3- yl]oxy...)
Affinity DataIC50:  590nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521066(7-(cyclohexylmethyl)-2-[6-(1,3- dimethylpyrazol-4-...)
Affinity DataIC50:  630nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521084(6-(2-chloro-5-fluoro-phenyl)-N-[[7- (tetrahydropyr...)
Affinity DataIC50:  730nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521058(2-[6-(2-chloro-5-fluoro-phenyl)pyridazin-3- yl]oxy...)
Affinity DataIC50:  760nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521086(6-(2-chloro-5-fluoro-phenyl)-N-[[7-[(2- fluorophen...)
Affinity DataIC50:  780nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521074(7-(cyclohexylmethyl)-2-[6-(2,4- dimethylpyrazol-3-...)
Affinity DataIC50:  850nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521063(2-[6-(2-chloro-5-fluoro-phenyl)pyridazin-3- yl]oxy...)
Affinity DataIC50:  900nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521013(N-[6-(1,3-dimethylpyrazol-4-yl)pyridazin- 3-yl]-7-...)
Affinity DataIC50:  1.02E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521094(6-(1,3-dimethylpyrazol-4-yl)-N-[[7-[(2- fluorophen...)
Affinity DataIC50:  1.12E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521048(N-[6-(2,4-dimethylpyrazol-3-yl)pyridazin- 3-yl]-7-...)
Affinity DataIC50:  1.12E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521059(2-[6-(2-chloro-5-fluoro-phenyl)pyridazin-3- yl]oxy...)
Affinity DataIC50:  1.14E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521090(N-[[7-(cyclohexylmethyl)-7- azaspiro[3.5]nonan-2-y...)
Affinity DataIC50:  1.16E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521069(2-[6-(1,3-dimethylpyrazol-4-yl)pyridazin-3- yl]oxy...)
Affinity DataIC50:  1.17E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521076(2-[6-(2,4-dimethylpyrazol-3-yl)pyridazin-3- yl]oxy...)
Affinity DataIC50:  1.21E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521062(7-benzyl-2-[6-(2-chloro-5-fluoro- phenyl)pyridazin...)
Affinity DataIC50:  1.27E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521104(2-[[6-(2-chloro-5-fluoro-phenyl)pyridazin- 3-yl]ox...)
Affinity DataIC50:  1.31E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521085(N-[(7-benzyl-7-azaspiro[3.5]nonan-2- yl)methyl]-6-...)
Affinity DataIC50:  1.34E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521102(2-[[6-(2-chloro-5-fluoro-phenyl)pyridazin- 3-yl]ox...)
Affinity DataIC50:  1.49E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521070(7-benzyl-2-[6-(1,3-dimethylpyrazol-4- yl)pyridazin...)
Affinity DataIC50:  1.63E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521036(N-[6-(1,3-dimethyipyrazol-4-yl)pyridazin- 3-yl]-7-...)
Affinity DataIC50:  1.74E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521088(6-(2-chloro-5-fluoro-phenyl)-N-[[7-[(6- methoxy-2-...)
Affinity DataIC50:  1.74E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521060(2-[6-(2-chloro-5-fluoro-phenyl)pyridazin-3- yl]oxy...)
Affinity DataIC50:  1.77E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521087(6-(2-chloro-5-fluoro-phenyl)-N-[[7-(2- pyridylmeth...)
Affinity DataIC50:  1.91E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521089(N-[[7-(1,3-benzodioxol-5-ylmethyl)-7- azaspiro[3.5...)
Affinity DataIC50:  2.02E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521103(2-[[6-(2-chloro-5-fluoro-phenyl)pyridazin- 3-yl]ox...)
Affinity DataIC50:  2.13E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521083(6-(2-chloro-5-fluoro-phenyl)-N-[[7- (tetrahydropyr...)
Affinity DataIC50:  2.28E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM521105(7-benzyl-2-[[6-(2-chIoro-5-fluoro- phenyl)pyridazi...)
Affinity DataIC50:  2.66E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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