Compile Data Set for Download or QSAR
Report error Found 82 Enz. Inhib. hit(s) with all data for entry = 10278
TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524403BDBM524403(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  15nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524401BDBM524401(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  32nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524437BDBM524437(2-((2S,4S)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524443BDBM524443(2-((2S,4R)-4-amino-1-(6- chloroquinoline-2-carbony...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524401BDBM524401(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524414BDBM524414(US11168083, Example 57 | 2-((2S,4R)-4-amino-1-(6- ...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524446BDBM524446(2-((2S,4R)-4-amino-1-(5- chlorobenzo[d]thiazole-2-...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524448BDBM524448(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524450BDBM524450(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524452BDBM524452(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524421BDBM524421(2-((2S,4R)-4-amino-1-(6- (trifluoromethyl)imidazo[...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524454BDBM524454(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524423BDBM524423(2-((2S,4R)-4-amino-1-(6- iodoimidazo[1,2-a]pyridin...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524424BDBM524424(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524425BDBM524425(N2-(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]p...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524460BDBM524460(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524442BDBM524442(2-((2S,4R)-4-amino-1-(3- chloroquinoline-6-carbony...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524445BDBM524445(2-((2S,4R)-4-amino-1-(5- chlorobenzo[b]thiophcne-2...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524415BDBM524415(2-((2S,4R)-4-amino-1-(imidazo[1,2- a]pyridine-2-ca...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524447BDBM524447(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524449BDBM524449(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524422BDBM524422(2-((2S,4R)-4-amino-1-(6- methoxyimidazo[1,2-a]pyri...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524403BDBM524403(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524426BDBM524426(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524461BDBM524461(2-((2S,4R)-4-amino-1-(5,6- dichlorobenzo[b]thiophe...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524462BDBM524462(2-((2S,4R)-4-amino-1-(6- chlorobenzo[b]thiophene-2...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524464BDBM524464(2-((2S,4R)-4-amino-1-(5- (trifluoromethyl)benzo[b]...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524465BDBM524465(2-((2S,4R)-4-amino-1-(6- methylbenzo[b]thiophene-2...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524466BDBM524466(2-((2S,4R)-4-amino-1-(6- chloroquinoline-3-carbony...)
Affinity DataEC50:  550nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524467BDBM524467(2-((2S,4R)-4-amino-1-(2- chloroquinoline-6-carbony...)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524436BDBM524436(2-((2S,4R)-4-acetamido-1-(6- chloroimidazo[1,2-a]p...)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524438BDBM524438(US11168083, Example 37)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524455BDBM524455(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524409BDBM524409(2-((2R,4S)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524441BDBM524441(2-((2S,4R)-1-(2-naphthoyl)-4- aminopyrrolidin-2-yl...)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524414BDBM524414(US11168083, Example 57 | 2-((2S,4R)-4-amino-1-(6- ...)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524463BDBM524463(2-((2S,4R)-4-amino-1-(4- chlorobenzo[b]thiophene-2...)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524418BDBM524418(3-chlorobenzyl (2S,4R)-4-amino-2-(4- (((S)-6-guani...)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524404BDBM524404(2-((2R,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524402BDBM524402(US11168083, Example 33)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524402BDBM524402(US11168083, Example 33)
Affinity DataEC50:  3.24E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524440BDBM524440(US11168083, Example 39)
Affinity DataEC50:  7.50E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524458BDBM524458(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  7.50E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524444BDBM524444(2-((2S,4R)-4-amino-1-(3- chlorobenzo[b]thiophene-6...)
Affinity DataEC50:  7.50E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524430BDBM524430(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  7.50E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524451BDBM524451(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  7.50E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524406BDBM524406(2-((R)-1-(6-Chloroimidazo[1,2-a]pyridine-2-carbony...)
Affinity DataEC50: >9.90E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524407BDBM524407(US11168083, Example 4)
Affinity DataEC50: >9.90E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524408BDBM524408(2-((2R,4R)-4-acetamido-1-(6- chloroimidazo[1,2-a]p...)
Affinity DataEC50: >9.90E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524439BDBM524439(US11168083, Example 38)
Affinity DataEC50: >9.90E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

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