Compile Data Set for Download or QSAR
Report error Found 596 Enz. Inhib. hit(s) with all data for entry = 10364
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436977BDBM436977(US10617676, Example 312 | 1-[(4-Methyl-3-pyridyl)m...)
Affinity DataIC50: 2nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436994BDBM436994(US10617676, Example 330 | 6-(3,4-Difluorophenyl)-1...)
Affinity DataIC50: 4nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436678BDBM436678(US10617676, Example 9 | 2-[6-(5-Chloro-2-thienyl)-...)
Affinity DataIC50: 5nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436762BDBM436762(US10617676, Example 93 | 1-[2-(Azetidin-1-yl)-2-ox...)
Affinity DataIC50: 6nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437086BDBM437086(US10617676, Example 423 | 2-[6-(2,4-Difluoro-3-met...)
Affinity DataIC50: 6nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436860BDBM436860(US10617676, Example 195 | N-(3,3-Difluorocyclobuty...)
Affinity DataIC50: 7nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436768BDBM436768(US10617676, Example 99 | 6-[5-(Difluoromethyl)-3-t...)
Affinity DataIC50: 7nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437073BDBM437073(US10617676, Example 409 | 1-[2-(Azetidin-1-yl)-2-o...)
Affinity DataIC50: 8nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437111BDBM437111(US10617676, Example 448 | 2-[6-(3-Chloro-4-fluoro-...)
Affinity DataIC50: 8nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437076BDBM437076(US10617676, Example 413 | 1-(2-(3,3-Difluoroazetid...)
Affinity DataIC50: 9nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436940BDBM436940(US10617676, Example 275 | 6-(3,4-Difluorophenyl)-1...)
Affinity DataIC50: 9nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436736BDBM436736(US10617676, Example 67 | 6-(2,4-Difluoro-3-methyl-...)
Affinity DataIC50: 9nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436719BDBM436719(US10617676, Example 50 | 6-(4-Fluoro-3-methyl-phen...)
Affinity DataIC50: 9nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436696BDBM436696(US10617676, Example 27 | US10617676, Example 120 |...)
Affinity DataIC50: 10nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436679BDBM436679(US10617676, Example 10 | 6-[5-(Difluoromethyl)-2-t...)
Affinity DataIC50: 10nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437079BDBM437079(US10617676, Example 416 | 1-[2-(3,3-Difluoroazetid...)
Affinity DataIC50: 10nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437085BDBM437085(US10617676, Example 422 | 1-[2-(Azetidin-1-yl)-2-o...)
Affinity DataIC50: 10nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436699BDBM436699(US10617676, Example 30 | 6-(2,4-Difluoro-3-methyl-...)
Affinity DataIC50: 11nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436995BDBM436995(US10617676, Example 331 | 6-(4-Fluoro-3-methyl-phe...)
Affinity DataIC50: 12nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436695BDBM436695(US10617676, Example 26 | N,N-Dimethyl-2-[2-oxo-6-[...)
Affinity DataIC50: 12nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437077BDBM437077(US10617676, Example 414 | 1-[2-(3,3-Difluoroazetid...)
Affinity DataIC50: 13nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436970BDBM436970(US10617676, Example 305 | 6-(3-Chlorophenyl)-1-[(5...)
Affinity DataIC50: 13nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436767BDBM436767(US10617676, Example 98 | 1-[2-(Azetidin-1-yl)-2-ox...)
Affinity DataIC50: 13nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437074BDBM437074(US10617676, Example 411 | 1-[2-(Azetidin-1-yl)-2-o...)
Affinity DataIC50: 14nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436986BDBM436986(US10617676, Example 321 | 2-[6-(5-Chloro-4-methyl-...)
Affinity DataIC50: 14nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437232BDBM437232(1-[2-(3-Fluoroazetidin-1-yl)-2-oxo-ethyl]-6-[5-(tr...)
Affinity DataIC50: 14nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437233BDBM437233(1-[2-(Azetidin-1-yl)-2-oxo-ethyl]-6-(2,4-difluoro-...)
Affinity DataIC50: 15nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437078BDBM437078(US10617676, Example 415 | 1-[2-(3,3-Difluoroazetid...)
Affinity DataIC50: 15nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437000BDBM437000(US10617676, Example 336 | (R/S)-6-(2,4-difluoro-3-...)
Affinity DataIC50: 15nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436766BDBM436766(US10617676, Example 97 | 2-[6-[5-(Difluoromethyl)-...)
Affinity DataIC50: 15nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436989BDBM436989(US10617676, Example 324 | 1-[2-(Azetidin-1-yl)-2-o...)
Affinity DataIC50: 15nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437044BDBM437044(US10617676, Example 380 | 6-(3-Chloro-4-fluoro-phe...)
Affinity DataIC50: 16nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437046BDBM437046(US10617676, Example 382 | 6-[4-Fluoro-3-(trifluoro...)
Affinity DataIC50: 16nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437066BDBM437066(US10617676, Example 402 | 1-[2-(3-Fluoroazetidin-1...)
Affinity DataIC50: 16nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437065BDBM437065(US10617676, Example 401 | 1-[2-(3-Fluoroazetidin-1...)
Affinity DataIC50: 16nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437196BDBM437196(6-[3-(Difluoromethoxy)-4-fluoro-phenyl]-3-methyl-1...)
Affinity DataIC50: 16nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437070BDBM437070(US10617676, Example 406 | 6-(3-Chlorophenyl)-1-[2-...)
Affinity DataIC50: 16nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436897BDBM436897(US10617676, Example 232 | 1-(Pyridazin-3-ylmethyl)...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436771BDBM436771(US10617676, Example 103 | 3-Methyl-1-(pyridazin-3-...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437254BDBM437254(6-(2,4-Difluoro-3-methyl-phenyl)-1-[2-(3-fluoroaze...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437064BDBM437064(US10617676, Example 400 | 6-(2,4-Difluoro-3-methyl...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436763BDBM436763(US10617676, Example 94 | 2-[6-[5-(Difluoromethyl)-...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437083BDBM437083(US10617676, Example 420 | 2-[6-(4-Fuoro-3-methyl-p...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436958BDBM436958(US10617676, Example 293 | 6-(2,4-Difluoro-3-methyl...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437053BDBM437053(US10617676, Example 389 | 6-(4-Fluoro-3-methyl-phe...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436895BDBM436895(US10617676, Example 230 | 1-(3-Pyridylmethyl)-6-[3...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436978BDBM436978(US10617676, Example 313 | 1-[(4-Methyl-3-pyridyl)m...)
Affinity DataIC50: 18nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437239BDBM437239(6-[3-(Difluoromethyl)-4-fluoro-phenyl]-1-[2-(3-flu...)
Affinity DataIC50: 18nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436770BDBM436770(US10617676, Example 101 | N,N-Dimethyl-2-[3-methyl...)
Affinity DataIC50: 19nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 437089BDBM437089(US10617676, Example 426 | 2-[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 19nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

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