Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 10431
TargetHistone deacetylase 6(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM534825(US11236052, Compound ID #1)
Affinity DataIC50:  6.40nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM534955(US11236052, Compound ID #3)
Affinity DataIC50:  14.5nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2)
Affinity DataIC50:  15nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM534825(US11236052, Compound ID #1)
Affinity DataIC50:  19nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2)
Affinity DataIC50:  68nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM534955(US11236052, Compound ID #3)
Affinity DataIC50:  79nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM534825(US11236052, Compound ID #1)
Affinity DataIC50:  130nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM534825(US11236052, Compound ID #1)
Affinity DataIC50:  137nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2)
Affinity DataIC50:  385nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM534955(US11236052, Compound ID #3)
Affinity DataIC50:  445nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM534955(US11236052, Compound ID #3)
Affinity DataIC50:  3.12E+3nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2)
Affinity DataIC50:  3.56E+3nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent