Compile Data Set for Download or QSAR
Report error Found 272 Enz. Inhib. hit(s) with all data for entry = 10447
TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 536025BDBM536025(US11242337, Example 128)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535974BDBM535974(US11242337, Example 127 | US11242337, Example 77)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 536026BDBM536026(US11242337, Example 129)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 536029BDBM536029(US11242337, Example 132)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 536031BDBM536031(US11242337, Example 134)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 536030BDBM536030(US11242337, Example 133)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 536033BDBM536033(US11242337, Example 136)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 536032BDBM536032(US11242337, Example 135)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 536035BDBM536035(US11242337, Example 142)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 536034BDBM536034(US11242337, Example 137)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 536037BDBM536037(US11242337, Example 146)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 536036BDBM536036(US11242337, Example 143)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 536038BDBM536038(US11242337, Example 154)
Affinity DataIC50: 100nMAssay Description:The ability of compounds to inhibit human and rat NHE-3-mediated Na+ dependent H+ antiport after application and washout was measured using a modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535886BDBM535886(US11242337, Example 1)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535908BDBM535908(US11242337, Example 18)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535912BDBM535912(US11242337, Example 21)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535914BDBM535914(US11242337, Example 23)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535913BDBM535913(US11242337, Example 22)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535916BDBM535916(US11242337, Example 25)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535915BDBM535915(US11242337, Example 24)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535918BDBM535918(US11242337, Example 27)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535917BDBM535917(US11242337, Example 26)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535920BDBM535920(US11242337, Example 29)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535919BDBM535919(US11242337, Example 28)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535923BDBM535923(US11242337, Example 31)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535921BDBM535921(US11242337, Example 30)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535925BDBM535925(US11242337, Example 33)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535924BDBM535924(US11242337, Example 32)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535888BDBM535888(US11242337, Example 3)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535887BDBM535887(US11242337, Example 2)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535890BDBM535890(US11242337, Example 5)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535889BDBM535889(US11242337, Example 4)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535892BDBM535892(US11242337, Example 7)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535894BDBM535894(US11242337, Example 9)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535896BDBM535896(US11242337, Example 11)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535895BDBM535895(US11242337, Example 10)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535899BDBM535899(US11242337, Example 12)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535904BDBM535904(US11242337, Example 17)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535903BDBM535903(US11242337, Example 16)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535944BDBM535944(US11242337, Example 51)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535943BDBM535943(US11242337, Example 50)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535946BDBM535946(US11242337, Example 53)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535945BDBM535945(US11242337, Example 52)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535948BDBM535948(US11242337, Example 55)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535947BDBM535947(US11242337, Example 54)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535950BDBM535950(US11242337, Example 57)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535949BDBM535949(US11242337, Example 56)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535955BDBM535955(US11242337, Example 59)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535952BDBM535952(US11242337, Example 58)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 535958BDBM535958(US11242337, Example 61)
Affinity DataIC50: 100nMAssay Description:Rat and human NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Paradi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

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