Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 10451
TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262124BDBM262124(6-Amino-9-[(4-bromophenyl)methyl]-2-(propylsulfoni...)
Affinity DataEC50:  9.60nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536318BDBM536318(US11242345, Example 9-B)
Affinity DataEC50:  11nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262106BDBM262106(6-Amino-9-[(4-chlorophenyl)methyl]-2-(propylsulfon...)
Affinity DataEC50:  12nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536317BDBM536317(US11242345, Example 9-A)
Affinity DataEC50:  14nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262122BDBM262122(6-Amino-2-(propylsulfonimidoyl)-9-[[4-(trifluorome...)
Affinity DataEC50:  16nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262112BDBM262112(6-Amino-9-[(6-chloro-3-pyridyl)methyl]-2-(propylsu...)
Affinity DataEC50:  17nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262131BDBM262131(6-Amino-9-[(4-chloro-3-fluorophenyl)methyl]-2-(pro...)
Affinity DataEC50:  18nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536339BDBM536339(US11242345, Example 29-A)
Affinity DataEC50:  19nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262125BDBM262125(6-Amino-9-[(3,4-dichlorophenyl)methyl]-2-(propylsu...)
Affinity DataEC50:  21nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262127BDBM262127(6-Amino-9-[(4-chloro-3-methyl-phenyl)methyl]-2-(pr...)
Affinity DataEC50:  21nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262137BDBM262137(6-Amino-9-[(3-chloro-4-methyl-phenyl)methyl]-2-(pr...)
Affinity DataEC50:  22nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536340BDBM536340(US11242345, Example 29-B)
Affinity DataEC50:  22nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262138BDBM262138(6-Amino-9-[(4-methylsulfonylphenyl)methyl]-2-(prop...)
Affinity DataEC50:  23nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262128BDBM262128(6-Amino-2-(propylsulfonimidoyl)-9-(p-tolylmethyl)-...)
Affinity DataEC50:  27nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262135BDBM262135(6-Amino-9-[(6-methyl-3-pyridyl)methyl]-2-(propylsu...)
Affinity DataEC50:  30nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262126BDBM262126(6-Amino-9-(3,4-difluorophenylmethyl)-2-(propylsulf...)
Affinity DataEC50:  36nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262123BDBM262123(6-Amino-9-[(4-fluorophenyl)methyl]-2-(propylsulfon...)
Affinity DataEC50:  37nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262132BDBM262132(6-Amino-9-[(2,4-difluorophenyl)methyl]-2-(propylsu...)
Affinity DataEC50:  40nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262121BDBM262121(6-Amino-9-[(3-chlorophenyl)methyl]-2-(propylsulfon...)
Affinity DataEC50:  42nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262111BDBM262111(6-Amino-9-[(4-chlorophenyl)methyl]-2-(methylsulfon...)
Affinity DataEC50:  43nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536328BDBM536328(Step 1: Preparation of 3-[[(6-chloro-5-nitro-2-pro...)
Affinity DataEC50:  47nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536357BDBM536357(US11242345, Example 70-A)
Affinity DataEC50:  54nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536343BDBM536343(4-[[6-Amino-8-oxo-2-(propylsulfonimidoyl)-7H-purin...)
Affinity DataEC50:  54nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262146BDBM262146(US9708325, 70 | 6-Amino-9-[(4-chlorophenyl)methyl]...)
Affinity DataEC50:  57nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262100BDBM262100(6-Amino-9-benzyl-2-(propylsulfonimidoyl)-7H-purin-...)
Affinity DataEC50:  65nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262110BDBM262110(6-Amino-2-(3-chloropropylsulfonimidoyl)-9-[(4-meth...)
Affinity DataEC50:  66nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262133BDBM262133(US9708325, 33 | & Example 33 | US9708325, 32 | US1...)
Affinity DataEC50:  66nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536311BDBM536311(US11242345, Example 4-A)
Affinity DataEC50:  67nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262117BDBM262117(and Example 18 | US9708325, 18 | US9708325, 17 | U...)
Affinity DataEC50:  68nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262109BDBM262109(6-Amino-9-[(4-methoxyphenyl)methyl]-2-(methylsulfo...)
Affinity DataEC50:  74nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262139BDBM262139(Methyl 4-[[6-amino-8-oxo-2-(propylsulfonimidoyl)-7...)
Affinity DataEC50:  75nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536358BDBM536358(US11242345, Example 70-B | CHEMBL5397718)
Affinity DataEC50:  77nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262142BDBM262142(6-Amino-9-[[4-(piperidine-1-carbonyl)phenyl]methyl...)
Affinity DataEC50:  84nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536312BDBM536312(US11242345, Example 4-B)
Affinity DataEC50:  86nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536361BDBM536361(US11242345, Example 71-B)
Affinity DataEC50:  87nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262143BDBM262143(6-Amino-2-(propylsulfonimidoyl)-9-[[4-(pyrrolidine...)
Affinity DataEC50:  90nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262149BDBM262149(US9708325, 71 | 6-Amino-2-(ethylsulfonimidoyl)-9-(...)
Affinity DataEC50:  98nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262136BDBM262136(6-Amino-9-[(2-methyl-4-pyridyl)methyl]-2-(propylsu...)
Affinity DataEC50:  120nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536360BDBM536360(US11242345, Example 71-A)
Affinity DataEC50:  134nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262145BDBM262145(6-Amino-9-[(2-methylpyrimidin-5-yl)methyl]-2-(prop...)
Affinity DataEC50:  136nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262141BDBM262141(4-[[6-Amino-8-oxo-2-(propylsulfonimidoyl)-7H-purin...)
Affinity DataEC50:  150nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536326BDBM536326(US11242345, Example 16-B)
Affinity DataEC50:  150nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262140BDBM262140(4-[[6-Amino-8-oxo-2-(propylsulfonimidoyl)-7H-purin...)
Affinity DataEC50:  170nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262105BDBM262105(6-Amino-9-benzyl-2-(2,2,2-trifluoroethylsulfonimid...)
Affinity DataEC50:  180nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 536305BDBM536305(US11242345, Example 1-B)
Affinity DataEC50:  180nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262113BDBM262113(6-Amino-9-[(2-chlorophenyl)methyl]-2-(propylsulfon...)
Affinity DataEC50:  190nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262096BDBM262096(6-Amino-9-benzyl-2-(ethylsulfonimidoyl)-7H-purin-8...)
Affinity DataEC50:  200nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262114BDBM262114(BDBM262115 | US9708325, 16 | 6-Amino-2-(methylsulf...)
Affinity DataEC50:  220nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262144BDBM262144(6-Amino-2-(propylsulfonimidoyl)-9-(pyrimidin-5-ylm...)
Affinity DataEC50:  240nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 262120BDBM262120(6-Amino-2-(methylsulfonimidoyl)-9-(4-pyridylmethyl...)
Affinity DataEC50:  260nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

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