Compile Data Set for Download or QSAR
Report error Found 103 Enz. Inhib. hit(s) with all data for entry = 10554
TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318915BDBM318915(US10172868, Compound C147 | N-(3-(2-((2-fluoro-4-(...)
Affinity DataIC50: 100nMAssay Description:EGFR: The 2×EGFR (ErbB1)/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 4 mM MnCl2, 1 mM EGTA, 2 mM DTT. The final 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318914BDBM318914(US10172868, Compound C145 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318915BDBM318915(US10172868, Compound C147 | N-(3-(2-((2-fluoro-4-(...)
Affinity DataIC50: 100nMAssay Description:BTK: The 2×BTK/Tyr 01 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The final 10 μL Kinase Reaction consists...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318915BDBM318915(US10172868, Compound C147 | N-(3-(2-((2-fluoro-4-(...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318916BDBM318916(US10172868, Compound C151 | N-(3-(2-((2,3-difluoro...)
Affinity DataIC50: 100nMAssay Description:EGFR: The 2×EGFR (ErbB1)/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 4 mM MnCl2, 1 mM EGTA, 2 mM DTT. The final 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318916BDBM318916(US10172868, Compound C151 | N-(3-(2-((2,3-difluoro...)
Affinity DataIC50: 100nMAssay Description:BTK: The 2×BTK/Tyr 01 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The final 10 μL Kinase Reaction consists...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318916BDBM318916(US10172868, Compound C151 | N-(3-(2-((2,3-difluoro...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318917BDBM318917(US10172868, Compound C156 | N-(3-(2-((2,3-difluoro...)
Affinity DataIC50: 100nMAssay Description:EGFR: The 2×EGFR (ErbB1)/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 4 mM MnCl2, 1 mM EGTA, 2 mM DTT. The final 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318917BDBM318917(US10172868, Compound C156 | N-(3-(2-((2,3-difluoro...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318900BDBM318900(US10172868, Compound C108 | N-(3-(2-((4-(2-hydroxy...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318901BDBM318901(US10172868, Compound C109 | N-(3-(2-((4-(2-(azetid...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318900BDBM318900(US10172868, Compound C108 | N-(3-(2-((4-(2-hydroxy...)
Affinity DataIC50: 100nMAssay Description:BTK: The 2×BTK/Tyr 01 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The final 10 μL Kinase Reaction consists...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318903BDBM318903(US10172868, Compound C118 | N-(3-(2-((4-((1-methyl...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318902BDBM318902(US10172868, Compound C110 | N-(3-(2-((4-(2-(dimeth...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318905BDBM318905(US10172868, Compound C123 | (R)-N-(3-(2-((4-((1-me...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318904BDBM318904(US10172868, Compound C121 | (S)-N-(3-(2-((4-((1-me...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318907BDBM318907(US10172868, Compound C127 | (S)-N-(3-(2-((4-((1-me...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318906BDBM318906(US10172868, Compound C126 | N-(3-(2-((4-((1-methyl...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318909BDBM318909(US10172868, Compound C137 | N-(3-(2-((4-((1-(2-hyd...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318908BDBM318908(US10172868, Compound C129 | (R)-N-(3-(2-((4-((1-me...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318911BDBM318911(US10172868, Compound C139 | N-(3-(2-((4-((1-(2-hyd...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318910BDBM318910(US10172868, Compound C138 | N-(3-(2-((4-((1-(2-flu...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318913BDBM318913(US10172868, Compound C141 | N-(3-(2-((2-fluoro-4-(...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318912BDBM318912(US10172868, Compound C140 | N-(3-(2-((2-fluoro-4-(...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318867BDBM318867(US10172868, Compound C003 | N-(3-(2-((2-methoxy-4-...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318866BDBM318866(US10172868, Compound C001 | N-(3-(2-((4-morpholino...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:EGFR: The 2×EGFR (ErbB1)/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 4 mM MnCl2, 1 mM EGTA, 2 mM DTT. The final 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:FGFR1: The 2×FGFR1/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 4 mM MnCl2, 1 mM EGTA, 2 mM DTT. The final 10 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:BTK: The 2×BTK/Tyr 01 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The final 10 μL Kinase Reaction consists...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:KDR: The 2×KDR (VEGFR2)/Tyr 01 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The final 10 μL Kinase Reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:FGFR2: The 2×FGFR2/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 4 mM MnCl2, 1 mM EGTA, 2 mM DTT. The final 10 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318874BDBM318874(US10172868, Compound C045 | N-(2-fluoro-3-(2-((4-(...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318873BDBM318873(US10172868, Compound C044 | N-(3-(2-((2-fluoro-4-(...)
Affinity DataIC50: 100nMAssay Description:JAK3: The 2×JAK3/Tyr 06 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The final 10 μL Kinase Reaction consis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318875BDBM318875(US10172868, Compound C048 | N-(2-fluoro-3-(2-((6-(...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318875BDBM318875(US10172868, Compound C048 | N-(2-fluoro-3-(2-((6-(...)
Affinity DataIC50: 100nMAssay Description:EGFR: The 2×EGFR (ErbB1)/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 4 mM MnCl2, 1 mM EGTA, 2 mM DTT. The final 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318877BDBM318877(US10172868, Compound C054 | N-(2-chloro-3-(2-((4-(...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318876BDBM318876(US10172868, Compound C049 | N-(3-(2-((4-(4-acetylp...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318879BDBM318879(US10172868, Compound C059 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:EGFR: The 2×EGFR (ErbB1)/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 4 mM MnCl2, 1 mM EGTA, 2 mM DTT. The final 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 549532BDBM549532(N-(4-(2-((4-(4-methylpiperazin-1-yl)phenyl)amino)q...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318879BDBM318879(US10172868, Compound C059 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:BTK: The 2×BTK/Tyr 01 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The final 10 μL Kinase Reaction consists...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318879BDBM318879(US10172868, Compound C059 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318879BDBM318879(US10172868, Compound C059 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:FGFR1: The 2×FGFR1/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 4 mM MnCl2, 1 mM EGTA, 2 mM DTT. The final 10 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318879BDBM318879(US10172868, Compound C059 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:JAK3: The 2×JAK3/Tyr 06 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The final 10 μL Kinase Reaction consis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318879BDBM318879(US10172868, Compound C059 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:KDR: The 2×KDR (VEGFR2)/Tyr 01 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The final 10 μL Kinase Reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:JAK3: The 2×JAK3/Tyr 06 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA. The final 10 μL Kinase Reaction consis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318870BDBM318870(US10172868, Compound C034 | N-(3-(7-methyl-2-((4-(...)
Affinity DataIC50: 100nMAssay Description:EGFR: The 2×EGFR (ErbB1)/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 4 mM MnCl2, 1 mM EGTA, 2 mM DTT. The final 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318869BDBM318869(US10172868, Compound C032 | N-(3-(2-((4-(4-acetylp...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318871BDBM318871(US10172868, Compound C040 | N-(5-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:EGFR: The 2×EGFR (ErbB1)/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 4 mM MnCl2, 1 mM EGTA, 2 mM DTT. The final 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318870BDBM318870(US10172868, Compound C034 | N-(3-(7-methyl-2-((4-(...)
Affinity DataIC50: 100nMAssay Description:EGFR (T790M)(L858R):The 2×EGFR (ErbB1) T790M L858R/Tyr 04 mixture is prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02% NaN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

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