Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 10609
TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397464BDBM397464(US9988375, Compound 43 | US10676470, Compound 43 |...)
Affinity DataIC50: 1nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397455BDBM397455(US9988375, Compound 32 | US10676470, Compound 32 |...)
Affinity DataIC50: 5.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397438BDBM397438(US9988375, Compound 9 | US10676470, Compound 9 | U...)
Affinity DataIC50: 5.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 554440BDBM554440(US11332464, Compound 34)
Affinity DataIC50: 5.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397456BDBM397456(US9988375, Compound 33 | US10676470, Compound 33 |...)
Affinity DataIC50: 5.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397440BDBM397440(US9988375, Compound 11 | US10676470, Compound 11 |...)
Affinity DataIC50: 5.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397435BDBM397435(US9988375, Compound 4 | US11332464, Compound 14)
Affinity DataIC50: 5.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 554441BDBM554441(US11332464, Compound 35)
Affinity DataIC50: 5.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 554381BDBM554381(US11332464, Compound 15)
Affinity DataIC50: 5.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397433BDBM397433(US9988375, Compound 2 | US10676470, Compound 2 | U...)
Affinity DataIC50: 5.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397449BDBM397449(US9988375, Compound 24 | US10676470, Compound 24 |...)
Affinity DataIC50: 5.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397435BDBM397435(US9988375, Compound 4 | US11332464, Compound 14)
Affinity DataIC50: 5.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397439BDBM397439(US9988375, Compound 10 | US10676470, Compound 10 |...)
Affinity DataIC50: 17.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397454BDBM397454(US9988375, Compound 31 | US10676470, Compound 31 |...)
Affinity DataIC50: 17.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397459BDBM397459(US9988375, Compound 38 | US10676470, Compound 38 |...)
Affinity DataIC50: 17.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 554400BDBM554400(US11332464, Compound 18)
Affinity DataIC50: 17.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397447BDBM397447(US9988375, Compound 22 | US10676470, Compound 22 |...)
Affinity DataIC50: 17.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397462BDBM397462(US9988375, Compound 41 | US10676470, Compound 41 |...)
Affinity DataIC50: 17.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 554411BDBM554411(US11332464, Compound 19)
Affinity DataIC50: 17.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397433BDBM397433(US9988375, Compound 2 | US10676470, Compound 2 | U...)
Affinity DataIC50: 17.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 450977BDBM450977(US10676470, Compound 15 | US11332464, Compound 3)
Affinity DataIC50: 17.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397437BDBM397437(US9988375, Compound 8 | US10676470, Compound 8 | U...)
Affinity DataIC50: 17.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397452BDBM397452(US9988375, Compound 29 | US10676470, Compound 29 |...)
Affinity DataIC50: 17.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397442BDBM397442(US9988375, Compound 13 | US10676470, Compound 13 |...)
Affinity DataIC50: 37.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397461BDBM397461(US9988375, Compound 40 | US10676470, Compound 40 |...)
Affinity DataIC50: 37.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397432BDBM397432(US9988375, Compound 1 | US10676470, Compound 1 | U...)
Affinity DataIC50: 37.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 554419BDBM554419(US11332464, Compound 26)
Affinity DataIC50: 37.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 554418BDBM554418(US11332464, Compound 25)
Affinity DataIC50: 37.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397453BDBM397453(US9988375, Compound 30 | US10676470, Compound 30 |...)
Affinity DataIC50: 37.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397436BDBM397436(US9988375, Compound 7 | US10676470, Compound 7 | U...)
Affinity DataIC50: 37.5nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397441BDBM397441(US9988375, Compound 12 | US10676470, Compound 12 |...)
Affinity DataIC50: 75nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397460BDBM397460(US9988375, Compound 39 | US10676470, Compound 39 |...)
Affinity DataIC50: 75nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397463BDBM397463(US9988375, Compound 42 | US10676470, Compound 42 |...)
Affinity DataIC50: 75nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 397432BDBM397432(US9988375, Compound 1 | US10676470, Compound 1 | U...)
Affinity DataIC50: 75nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 14297BDBM14297(benzyl N-[(2S)-6-amino-1-(1,3-benzothiazol-2-yl)-1...)
Affinity DataIC50: 175nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandChemical structure of BindingDB Monomer ID 450998BDBM450998(US10676470, Compound 44 | US11332464, Compound 44)
Affinity DataIC50: 250nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent