Compile Data Set for Download or QSAR
Report error Found 605 Enz. Inhib. hit(s) with all data for entry = 10650
TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283066BDBM283066(6-(1-(1-cyanocyclopropyl)-4-(4-fluorophenyl)-1H- i...)
Affinity DataIC50: 0.300nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282914BDBM282914(6-(4-(3-chloro-4-fluorophenyl)-1-ethyl-1H-imidazol...)
Affinity DataIC50: 0.400nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282817BDBM282817(6-(4-(4-fluorophenyl)-1-isopropyl-1H-imidazol-5- y...)
Affinity DataIC50: 0.400nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282966BDBM282966(6-(4-(4-fluorophenyl)-1-isopropyl-1H-imidazol-5- y...)
Affinity DataIC50: 0.5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282968BDBM282968(6-(1-cyclobutyl-4-(4-fluorophenyl)-1H-imidazol-5- ...)
Affinity DataIC50: 0.5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282899BDBM282899(6-(4-(3-chloro-4-fluorophenyl)-1-(3-fluorocyclobut...)
Affinity DataIC50: 0.5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282844BDBM282844(6-(4-(3-chloro-4-fluorophenyl)-1-isopropyl-1H- imi...)
Affinity DataIC50: 0.600nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282820BDBM282820(6-(4-(4-fluorophenyl)-1-(3- (hydroxymethyl)cyclobu...)
Affinity DataIC50: 0.600nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282912BDBM282912(6-(4-(3-chloro-4-fluorophenyl)-1-ethyl-1H-imidazol...)
Affinity DataIC50: 0.600nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282970BDBM282970(6-(1-(sec-butyl)-4-(4-fluorophenyl)-1H-imidazol-5-...)
Affinity DataIC50: 0.600nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282947BDBM282947(6-(4-(3-chloro-4-fluorophenyl)-1-(2,2-difluoroprop...)
Affinity DataIC50: 0.600nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282963BDBM282963(6-(1-(1-cyclopropylethyl)-4-(4-fluorophenyl)-1H- i...)
Affinity DataIC50: 0.600nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283030BDBM283030(6-(4-(3-chloro-4-fluorophenyl)-1-(2,2-difluoroethy...)
Affinity DataIC50: 0.600nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282833BDBM282833(6-(4-(3-chloro-4-fluorophenyl)-1-(2-cylcobutylethy...)
Affinity DataIC50: 0.600nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282932BDBM282932(6-(1-(2,2-difluoropropyl)-4-(4-fluorophenyl)-1H- i...)
Affinity DataIC50: 0.600nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282933BDBM282933(6-(4-(3-chloro-4-fluorophenyl)-1-(2-hydroyxethyl)-...)
Affinity DataIC50: 0.700nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282930BDBM282930(6-(4-(4-fluorophenyl)-1-isopropyl-1H-imidazol-5- y...)
Affinity DataIC50: 0.700nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283047BDBM283047(6-(1-(2,2-difluoroethyl)-4-(2-hydroxyphenyl)-1H- i...)
Affinity DataIC50: 0.700nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282907BDBM282907(6-(1-ethyl-4-(4-fluorophenyl)-1H-imidazol-5- yl)im...)
Affinity DataIC50: 0.700nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283007BDBM283007(6-(1-(2,2-difluoroethyl)-4-(4-fluorophenyl)-1H- im...)
Affinity DataIC50: 0.700nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282852BDBM282852(6-(4-(3-chloro-4-fluorophenyl)-1-cyclobutyl-1H- im...)
Affinity DataIC50: 0.800nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282936BDBM282936(6-(4-(3-chloro-4-fluorophenyl)-1-(3-fluorocyclobut...)
Affinity DataIC50: 0.800nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282953BDBM282953(6-(1-(cylcobutylmethyl)-4-(4-fluorophenyl)-1H- imi...)
Affinity DataIC50: 0.800nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282856BDBM282856(6-(4-(3-chloro-4-fluorophenyl)-1-(2-cyclopropyleth...)
Affinity DataIC50: 0.800nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282848BDBM282848(6-(4-(3-chloro-4-fluorophenyl)-1-(3-fluoropropyl)-...)
Affinity DataIC50: 0.800nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282955BDBM282955(6-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-...)
Affinity DataIC50: 0.800nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283013BDBM283013(6-(1-(2,2-difluoroethyl)-4-(4-fluorophenyl)-1H- im...)
Affinity DataIC50: 0.800nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282906BDBM282906(6-(1-(2-fluoroethyl)-4-(4-fluorophenyl)-1H-imidazo...)
Affinity DataIC50: 0.800nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282956BDBM282956(6-(1-ethyl-4-(4-fluorophenyl)-1H-imidazol-5- yl)im...)
Affinity DataIC50: 0.800nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282850BDBM282850(6-(4-(3-chloro-4-fluorophenyl)-1-(2,2-difluoroprop...)
Affinity DataIC50: 0.800nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282827BDBM282827(6-(4-(3-chloro-4-fluorophenyl)-1-(2-fluoroethyl)-1...)
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283083BDBM283083(6-(2-(4-fluorophenyl)-6,7-dihydro-5H-pyrrolo[1,2- ...)
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282845BDBM282845(6-(4-(3-chloro-4-fluorophenyl)-1-ethyl-1H-imidazol...)
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282855BDBM282855(6-(4-(3-chloro-4-fluorophenyl)-1-(2-chloroethyl)-1...)
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282911BDBM282911(6-(4-(3-chloro-4-fluorophenyl)-1-isopropyl-1H- imi...)
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283004BDBM283004(6-(1-(2,2-difluoroethyl)-4-(4-fluorophenyl)-1H- im...)
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282832BDBM282832(6-(4-(3-chloro-4-fluorophenyl)-1-((cis)-3- hydroxy...)
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282858BDBM282858((R)-6-(4-(3-chloro-4-fluorophenyl)-1-(3,3- difluor...)
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283015BDBM283015(5-(6-(1-(2,2-difluoroethyl)-4-(4-fluorophenyl)-1H-...)
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282834BDBM282834(6-(4-(3-chloro-4-fluorophenyl)-1-(1- methylcyclopr...)
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282900BDBM282900(6-(4-(3-Chlorophenyl)-2-methyl-1H-imidazol-5- yl)q...)
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282908BDBM282908(6-(4-(3-chloro-4-fluorophenyl)-1-(2,2-difluoroethy...)
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282826BDBM282826(6-(4-(3-chloro-4-fluorophenyl)-1-(2,2-difluoroethy...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283034BDBM283034(6-(4-(5-chloro-2,4-difluorophenyl)-1-(2,2- difluor...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283058BDBM283058(6-(1-(2,2-difluoroethyl)-4-(3- (trifluoromethoxy)p...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282821BDBM282821((R)-6-(4-(4-fluorophenyl)-1-(4,4,4-trifluoro-1- hy...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 282831BDBM282831(6-(4-(3-chloro-4-fluorophenyl)-1-(3-hydroxypropyl)...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283032BDBM283032(6-(1-(2,2-difluoroethyl)-4-(2,4-difluorophenyl)-1H...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283033BDBM283033(6-(4-(5-chloro-2-fluorophenyl)-1-(2,2-difluoroethy...)
Affinity DataIC50: 1.10nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Syngene International

US Patent
LigandChemical structure of BindingDB Monomer ID 283001BDBM283001(6-(1-(2,2-difluoroethyl)-4-(4-fluorophenyl)-1H- im...)
Affinity DataIC50: 1.10nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2022
Entry Details
US Patent

Displayed 1 to 50 (of 605 total ) | Next | Last >>
Jump to: