Compile Data Set for Download or QSAR
Report error Found 154 Enz. Inhib. hit(s) with all data for entry = 10669
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558701BDBM558701(US11365204, Example 56 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558701BDBM558701(US11365204, Example 56 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558700BDBM558700(US11365204, Example 55 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558700BDBM558700(US11365204, Example 55 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558703BDBM558703(US11365204, Example 58 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558703BDBM558703(US11365204, Example 58 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558702BDBM558702(US11365204, Example 57 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558702BDBM558702(US11365204, Example 57 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558705BDBM558705(US11365204, Example 60 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558705BDBM558705(US11365204, Example 60 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558704BDBM558704(US11365204, Example 59 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558704BDBM558704(US11365204, Example 59 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558707BDBM558707(US11365204, Example 62 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558707BDBM558707(US11365204, Example 62 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558706BDBM558706(US11365204, Example 61 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558706BDBM558706(US11365204, Example 61 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558693BDBM558693(US11365204, Example 48 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558693BDBM558693(US11365204, Example 48 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558692BDBM558692(US11365204, Example 47 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558692BDBM558692(US11365204, Example 47 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558694BDBM558694(US11365204, Example 49 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558694BDBM558694(US11365204, Example 49 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558697BDBM558697(US11365204, Example 52 | O1-methyl O4-[1-[4- [meth...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558697BDBM558697(US11365204, Example 52 | O1-methyl O4-[1-[4- [meth...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558696BDBM558696(US11365204, Example 51 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558696BDBM558696(US11365204, Example 51 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558699BDBM558699(US11365204, Example 54 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558699BDBM558699(US11365204, Example 54 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558698BDBM558698(US11365204, Example 53 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558698BDBM558698(US11365204, Example 53 | [1-[4-[methyl(tetra- hydr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558717BDBM558717(US11365204, Example 72 | [1-[4-[[(3S)-1-acetyl- py...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558717BDBM558717(US11365204, Example 72 | [1-[4-[[(3S)-1-acetyl- py...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558719BDBM558719(US11365204, Example 74 | [1-[4-[[(3S)-1-acetyl- py...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558718BDBM558718(US11365204, Example 73 | [1-[4-[[(3S)-1-acetyl- py...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558709BDBM558709(US11365204, Example 67 | [1-[(5R)-4-[methyl- (tetr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558709BDBM558709(US11365204, Example 67 | [1-[(5R)-4-[methyl- (tetr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558708BDBM558708(US11365204, Example 63 | [1-[(5R)-4-[methyl- (tetr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558711BDBM558711(US11365204, Example 66 | [1-[4-(6-oxaspiro[3.3]- h...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558711BDBM558711(US11365204, Example 66 | [1-[4-(6-oxaspiro[3.3]- h...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558710BDBM558710(US11365204, Example 65 | [1-[4-(6-oxaspiro[3.3]- h...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558710BDBM558710(US11365204, Example 65 | [1-[4-(6-oxaspiro[3.3]- h...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558713BDBM558713([1-[(5R)-4-(6-oxaspiro- [3.3]heptan-2-ylamino)-5- ...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558713BDBM558713([1-[(5R)-4-(6-oxaspiro- [3.3]heptan-2-ylamino)-5- ...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558709BDBM558709(US11365204, Example 67 | [1-[(5R)-4-[methyl- (tetr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558709BDBM558709(US11365204, Example 67 | [1-[(5R)-4-[methyl- (tetr...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558715BDBM558715(US11365204, Example 71 | [1-[(5R)-4-(6-oxaspiro- [...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558715BDBM558715(US11365204, Example 71 | [1-[(5R)-4-(6-oxaspiro- [...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558656BDBM558656(US11365204, Example 11 | [1-[(5R)-5-oxido-4- (tetr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558656BDBM558656(US11365204, Example 11 | [1-[(5R)-5-oxido-4- (tetr...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 558657BDBM558657(US11365204, Example 12 | [1-[(5R)-5-oxido-4- (tetr...)
Affinity DataIC50: 100nMAssay Description:Human peripheral blood mononuclear cells (PBMC) were isolated from fresh buffy coats by density centrifugation using lymphoprep tubes (Medinor). Froz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

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