Compile Data Set for Download or QSAR
Report error Found 199 Enz. Inhib. hit(s) with all data for entry = 10712
TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479055BDBM479055((R)-N-(4-(3-((5-chloro-4- phenoxypyrimidin-2- yl)a...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479056BDBM479056((R)-N-(4-(3-((5-chloro-4- ethoxypyrimidin-2- yl)am...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479007BDBM479007(US10894788, Example 47 | US10894788, Example 138 |...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479064BDBM479064((R)-N-(4-(3-((5-bromopyrimidin-2- yl)amino)pyrroli...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479062BDBM479062((R)-N-(4-(3-((5-chloro-4-(2- cyanoethoxy)pyrimidin...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479039BDBM479039((R)-N-(2-methyl-4-(3-((5- (trifluoromethyl)pyrimid...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479038BDBM479038((R)-N-(4-(3-((5-chloro-4- methoxypyrimidin-2- yl)a...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479048BDBM479048((R)-N-(4-(3-((5-chloro-4-(2- methoxyethoxy)pyrimid...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479046BDBM479046(US10894788, Example 86 | US10894788, Example 139 |...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479051BDBM479051((R)-N-(4-(3-((4-amino-5- (trifluoromethyl)pyrimidi...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479052BDBM479052((R)-N-(4-(3-((5-chloro-4- (trifluoromethyl)pyrimid...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479050BDBM479050((R)-N-(4-(3-((4-amino-5- chloropyrimidin-2- yl)ami...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478974BDBM478974((R)-N-(4-(3-((5-bromo-4- methoxypyrimidin-2- yl)am...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479085BDBM479085((R)-N-(4-(3-((5-chloropyrimidin-2- yl)amino)pyrrol...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478974BDBM478974((R)-N-(4-(3-((5-bromo-4- methoxypyrimidin-2- yl)am...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478980BDBM478980((R)-N-(4-(3-((5-bromo-4- methoxypyrimidin-2- yl)am...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478980BDBM478980((R)-N-(4-(3-((5-bromo-4- methoxypyrimidin-2- yl)am...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478979BDBM478979((R)-N-(4-(3-((5-bromopyrimidin-2- yl)amino)pyrroli...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478979BDBM478979((R)-N-(4-(3-((5-bromopyrimidin-2- yl)amino)pyrroli...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479046BDBM479046(US10894788, Example 86 | US10894788, Example 139 |...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478984BDBM478984((R)-N-(4-(3-((5-chloro-4-(2,2,2- trifluoroethoxy)p...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478981BDBM478981(US10894788, Example 21 | US10894788, Example 56 | ...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479097BDBM479097((R)-N-(4-(3-((5-chloro-4-(2- hydroxyethoxy)pyrimid...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479007BDBM479007(US10894788, Example 47 | US10894788, Example 138 |...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479022BDBM479022(US10894788, Example 62 | (R)-N-(4-(3-((5-chloro-4-...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478963BDBM478963(US10894788, Example 3 | US10894788, Example 65 | (...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478961BDBM478961((R)-N-(4-(3-((5-chloro-4- methoxypyrimidin-2- yl)a...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478967BDBM478967(US10894788, Example 7 | US10894788, Example 67 | (...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479080BDBM479080((R)-N-(4-(3-((4-(methylamino)-5- (trifluoromethyl)...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478965BDBM478965(US10894788, Example 5 | US10894788, Example 66 | (...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478966BDBM478966(US10894788, Example 6 | US10894788, Example 72 | (...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478971BDBM478971(US10894788, Example 11 | (R)-N-(4-(3-((5-chloro-4-...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479084BDBM479084(US10894788, Example 124 | (R)-N-(4-(3-((5-chloro-4...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479038BDBM479038((R)-N-(4-(3-((5-chloro-4- methoxypyrimidin-2- yl)a...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478970BDBM478970(US10894788, Example 10 | US10894788, Example 68 | ...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479117BDBM479117((R)-N-(4-(3-((5-bromopyrimidin-2- yl)amino)pyrroli...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479123BDBM479123(N-(4-((R)-3-((5-bromopyrimidin-2- yl)amino)pyrroli...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479124BDBM479124((R)-N-(4-(3-((5-cyano-4- methoxypyrimidin-2- yl)am...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479122BDBM479122(N-(4-((R)-3-((5-bromopyrimidin-2- yl)amino)pyrroli...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479007BDBM479007(US10894788, Example 47 | US10894788, Example 138 |...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479007BDBM479007(US10894788, Example 47 | US10894788, Example 138 |...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479128BDBM479128((E)-N-(4-((R)-3-((5-chloro-4- methoxypyrimidin-2- ...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479126BDBM479126((E)-N-(4-((R)-3-((5-chloro-4- methoxypyrimidin-2- ...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478990BDBM478990(US10894788, Example 30 | US10894788, Example 50 | ...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478987BDBM478987(US10894788, Example 27 | (R)-1-(5-(3-((5-chloro-4-...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478986BDBM478986((R)-N-(4-(3-((5-chloro-4- methoxypyrimidin-2- yl)a...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479103BDBM479103(N-(4-((R)-3-((5-chloro-4- ethoxypyrimidin-2- yl)am...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478986BDBM478986((R)-N-(4-(3-((5-chloro-4- methoxypyrimidin-2- yl)a...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 479104BDBM479104((R)-N-(4-(3-((5-chloro-4- ethoxypyrimidin-2- yl)am...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 478985BDBM478985((R)-N-(4-(3-((5-chloro-4- methoxypyrimidin-2- yl)a...)
Affinity DataIC50: 100nMAssay Description:The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

Displayed 1 to 50 (of 199 total ) | Next | Last >>
Jump to: