Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 10717
LigandChemical structure of BindingDB Monomer ID 561983BDBM561983(US11396496, Compound A1 | BDBM50369389)
Affinity DataIC50: 63nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561992BDBM561992(US11396496, Compound B0 | BDBM50537618)
Affinity DataIC50: 74nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 561995BDBM561995(US11396496, Compound C3 | BDBM50538487)
Affinity DataIC50: 167nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561988BDBM561988(US11396496, Compound A6 | BDBM50537615)
Affinity DataIC50: 212nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561987BDBM561987(US11396496, Compound A5 | BDBM50537610)
Affinity DataIC50: 350nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561986BDBM561986(US11396496, Compound A4 | BDBM50537611)
Affinity DataIC50: 530nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561994BDBM561994(US11396496, Compound C2 | BDBM50538480)
Affinity DataIC50: 698nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561996BDBM561996(US11396496, Compound C4)
Affinity DataIC50: 938nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561990BDBM561990(BDBM561991 | BDBM50537617 | US11396496, Compound A...)
Affinity DataIC50: 1.10E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561984BDBM561984(US11396496, Compound A2 | BDBM50537614)
Affinity DataIC50: 1.20E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561990BDBM561990(BDBM561991 | BDBM50537617 | US11396496, Compound A...)
Affinity DataIC50: 1.23E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561985BDBM561985(US11396496, Compound A3)
Affinity DataIC50: 2.00E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561989BDBM561989(US11396496, Compound A7 | BDBM50537616)
Affinity DataIC50: 2.30E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50538479BDBM50538479(CHEMBL4634320 | US11396496, Compound C1)
Affinity DataIC50: 2.90E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561998BDBM561998(US11396496, Compound C6)
Affinity DataIC50: 5.00E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 562004BDBM562004(US11396496, Compound C12 | BDBM50538484)
Affinity DataIC50: 5.60E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50538485BDBM50538485(CHEMBL4647075 | US11396496, Compound C11)
Affinity DataIC50: 6.00E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50538483BDBM50538483(CHEMBL4649100 | US11396496, Compound C9)
Affinity DataIC50: 9.30E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 562002BDBM562002(US11396496, Compound C10 | BDBM50538482)
Affinity DataIC50: 1.10E+4nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561999BDBM561999(US11396496, Compound C7)
Affinity DataIC50: 2.50E+4nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 561997BDBM561997(US11396496, Compound C5)
Affinity DataIC50: 2.50E+4nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 562000BDBM562000(US11396496, Compound C8)
Affinity DataIC50: 2.50E+4nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 562006BDBM562006(US11396496, Compound C14 | BDBM50538481)
Affinity DataIC50: 2.50E+4nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 562005BDBM562005(US11396496, Compound C13)
Affinity DataIC50: 2.50E+4nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent