Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 10746
LigandPNGBDBM563325(2-(8-(cyanomethyl)-6-{[(2-hydroxyethyl)amino]methy...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563323(2-(8-chloro-6-{[(2-hydroxyethyl)amino]methyl}[1,2,...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563324(2-[2-cyano-3-(2,3-dihydro-1,4-benzodioxin-6-yl)phe...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563314(2-({[2-(2-methylbiphenyl-3-yl)[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563311(2-({[2-(2-methylbiphenyl-3-yl)imidazo[1,2-a]pyrazi...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563318(2-({[5-methyl-2-(2-methylbiphenyl-3-yl)[1,2,4]tria...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563316(2-({[2-(2-methylbiphenyl-3-yl)[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563321(4-[6-{[(2-hydroxyethyl)amino]methyl}-2-(2-methylbi...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563322([6-{[(2-hydroxyethyl)amino]methyl}-2-(2-methylbiph...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563319(2-({[8-chloro-2-(2-methylbiphenyl-3-yl)-[1,2,4]tri...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM50540066(CHEMBL4639107 | US11407749, Example 5)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563309(2-((8-chloro-2-(2-methylbiphenyl-3-yl)imidazo[1,2-...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563310(2-({[2-(2-methylbiphenyl-3-yl)imidazo[1,2-a]pyrimi...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563307(2-((8-methyl-2-(2-methylbiphenyl-3-yl)imidazo[1,2-...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563308((S)-1-((8-methyl-2-(2-methylbiphenyl-3-yl)imidazo[...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563313(2-({[2-(2-methylbiphenyl-3-yl)imidazo[1,2-b]pyrida...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563317((2S)-1-{[2-(2-methylbiphenyl-3-yl)[1,2,4]triazolo[...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563315((2S)-1-{[2-(2-methylbiphenyl-3-yl)[1,2,4]triazolo[...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563320(2-({[8-[(2-methoxyethyl)amino]-2-(2-methylbiphenyl...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563301((2S)-1-{[2-(2-methylbiphenyl-3-yl)indolizin-7-yl]m...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563299(2-({[2-(2-methylbiphenyl-3-yl)imidazo[1,2-a]pyridi...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563300(2-({[2-(2-methylbiphenyl-3-yl)indolizin-7-yl]methy...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563305(2-((6-(2-methylbiphenyl-3-yl)imidazo[1,2-b][1,2,4]...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563306(2-(methyl((6-(2-methylbiphenyl-3-yl)imidazo[1,2-b]...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563304(2-((6-(2-methylbiphenyl-3-yl)imidazo[1,2-b][1,2,4]...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563312((S)-1-((2-(2-methylbiphenyl-3-yl)imidazo[1,2-b]pyr...)
Affinity DataIC50: 5.25E+3nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

LigandPNGBDBM563302((2S)-1-{[6-(2-methylbiphenyl-3-yl)pyrrolo[1,2-c]py...)
Affinity DataIC50: 5.25E+3nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent