Compile Data Set for Download or QSAR
Report error Found 89 Enz. Inhib. hit(s) with all data for entry = 10760
TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565148BDBM565148(US11414404, Ex. # 25 | US11634409, Example 25)
Affinity DataIC50: 0.340nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565192BDBM565192(US11414404, Ex. # 69 | US11634409, Example 69)
Affinity DataIC50: 0.460nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565143BDBM565143(US11414404, Ex. # 20 | US11634409, Example 20)
Affinity DataIC50: 0.700nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565130BDBM565130(US11414404, Ex. # 7 | US11634409, Example 7)
Affinity DataIC50: 1.30nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565131BDBM565131(US11414404, Ex. # 8 | US11634409, Example 8)
Affinity DataIC50: 1.45nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565196BDBM565196(US11414404, Ex. # 73 | US11634409, Example 73)
Affinity DataIC50: 1.55nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565129BDBM565129(US11414404, Ex. # 6 | US11634409, Example 6)
Affinity DataIC50: 1.75nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565190BDBM565190(US11414404, Ex. # 67 | US11634409, Example 67)
Affinity DataIC50: 2nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565151BDBM565151(US11414404, Ex. # 28 | US11634409, Example 28)
Affinity DataIC50: 2nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600K](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565130BDBM565130(US11414404, Ex. # 7 | US11634409, Example 7)
Affinity DataIC50: 2.20nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600K](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565186BDBM565186(US11414404, Ex. # 63 | US11634409, Example 63)
Affinity DataIC50: 2.40nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565193BDBM565193(US11414404, Ex. # 70 | US11634409, Example 70)
Affinity DataIC50: 2.55nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600K](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565133BDBM565133(US11414404, Ex. # 10 | BDBM565146 | US11634409, Ex...)
Affinity DataIC50: 2.70nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf [V600K](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565133BDBM565133(US11414404, Ex. # 10 | BDBM565146 | US11634409, Ex...)
Affinity DataIC50: 2.70nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf [V600K](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565190BDBM565190(US11414404, Ex. # 67 | US11634409, Example 67)
Affinity DataIC50: 2.80nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565186BDBM565186(US11414404, Ex. # 63 | US11634409, Example 63)
Affinity DataIC50: 2.80nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565171BDBM565171(US11414404, Ex. # 48 | N-(2,5-dichloro-3-((3,5- di...)
Affinity DataIC50: 3nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600K](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565178BDBM565178(US11414404, Ex. # 55 | US11634409, Example 55)
Affinity DataIC50: 3.10nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565133BDBM565133(US11414404, Ex. # 10 | BDBM565146 | US11634409, Ex...)
Affinity DataIC50: 3.25nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565182BDBM565182(US11414404, Ex. # 59 | N-(2-chloro-4-fluoro-3-((5-...)
Affinity DataIC50: 3.40nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565197BDBM565197(US11414404, Ex. # 74 | US11634409, Example 74)
Affinity DataIC50: 3.55nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565172BDBM565172(US11414404, Ex. # 49 | N-(2-chloro-3-((3,5- dimeth...)
Affinity DataIC50: 3.95nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565189BDBM565189(US11414404, Ex. # 66 | US11634409, Example 66)
Affinity DataIC50: 4.08nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565133BDBM565133(US11414404, Ex. # 10 | BDBM565146 | US11634409, Ex...)
Affinity DataIC50: 4.25nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565200BDBM565200(US11414404, Ex. # 77 | US11634409, Example 77)
Affinity DataIC50: 4.25nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565138BDBM565138(US11414404, Ex. # 15 | US11634409, Example 15)
Affinity DataIC50: 4.55nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565136BDBM565136(US11414404, Ex. # 13 | US11634409, Example 13)
Affinity DataIC50: 4.60nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565199BDBM565199(US11414404, Ex. # 76 | US11634409, Example 76)
Affinity DataIC50: 5.10nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565178BDBM565178(US11414404, Ex. # 55 | US11634409, Example 55)
Affinity DataIC50: 5.40nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565160BDBM565160(US11414404, Ex. # 37 | N-(2-chloro-3-((3-ethyl-5- ...)
Affinity DataIC50: 5.5nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565167BDBM565167(US11414404, Ex. # 44 | N-(2-chloro-3-((3,5- dimeth...)
Affinity DataIC50: 6.05nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565142BDBM565142(US11414404, Ex. # 19 | US11634409, Example 19)
Affinity DataIC50: 6.20nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565128BDBM565128(US11414404, Ex. # 5 | US11634409, Example 5)
Affinity DataIC50: 6.25nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600K](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565132BDBM565132(US11414404, Ex. # 9 | BDBM565147 | US11634409, Exa...)
Affinity DataIC50: 6.5nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565195BDBM565195(US11414404, Ex. # 72 | US11634409, Example 72)
Affinity DataIC50: 7.70nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565141BDBM565141(US11414404, Ex. # 18 | US11634409, Example 18)
Affinity DataIC50: 7.85nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600K](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565127BDBM565127(US11414404, Ex. # 4 | US11634409, Example 4)
Affinity DataIC50: 8.10nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600K](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565094BDBM565094(US11414404, Ex. # 1 | US11634409, Example 1)
Affinity DataIC50: 8.5nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565202BDBM565202(US11414404, Ex. # 79 | US11634409, Example 79)
Affinity DataIC50: 8.55nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565157BDBM565157(US11414404, Ex. # 34 | (R)-N-(2-chloro-4-fluoro-3-...)
Affinity DataIC50: 8.90nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565132BDBM565132(US11414404, Ex. # 9 | BDBM565147 | US11634409, Exa...)
Affinity DataIC50: 9.05nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565183BDBM565183(US11414404, Ex. # 60 | N-(2-chloro-3-((5-ethynyl- ...)
Affinity DataIC50: 9.25nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565176BDBM565176(US11414404, Ex. # 53 | N-(2-cyano-3-((3,5- dimethy...)
Affinity DataIC50: 9.40nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565140BDBM565140(US11414404, Ex. # 17 | US11634409, Example 17)
Affinity DataIC50: 9.70nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565135BDBM565135(US11414404, Ex. # 12 | US11634409, Example 12)
Affinity DataIC50: 9.75nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565187BDBM565187(US11414404, Ex. # 64 | US11634409, Example 64)
Affinity DataIC50: 10.4nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565201BDBM565201(US11414404, Ex. # 78 | US11634409, Example 78)
Affinity DataIC50: 10.8nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565179BDBM565179(US11414404, Ex. # 56 | US11634409, Example 56)
Affinity DataIC50: 12.9nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565145BDBM565145(US11414404, Ex. # 22 | US11634409, Example 22 | US...)
Affinity DataIC50: 13.7nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 565137BDBM565137(US11414404, Ex. # 14 | US11634409, Example 14)
Affinity DataIC50: 13.9nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

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