Compile Data Set for Download or QSAR
Report error Found 149 Enz. Inhib. hit(s) with all data for entry = 10854
LigandPNGBDBM463543(US10781185, Example 97 | 3-(Isopropyl(methyl)amino...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463544(US10781185, Example 98 | US11459307, Example 98)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463541(US10781185, Example 95 | 2-(Benzo[d][1,3]dioxol-5-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463542(US10781185, Example 96 | 3-(Octahydroquinolin-1(2H...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463547(3-(1,1-Dioxidothiomorpholino)-2-(4-fluorophenyl)qu...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463548(3-(1,1-Dioxidothiomorpholino)-2-phenylquinoxaline-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463545(US10781185, Example 99 | 3-(Isopropyl(methyl)amino...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463546(3-(Isopropyl(methyl)amino)-2-(4-morpholinophenyl)q...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463551(2-(4-Fluorophenyl)-3-(methyl(tetrahydro-2H-pyran-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463552(3-(Cyclopentyl(methyl)amino)-2-(4-fluorophenyl)qui...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463549(2-(4-Fluorophenyl)-3-(3-oxopiperazin-1-yl)quinoxal...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463550(2-(4-Fluorophenyl)-3-(methyl(piperidin-4-yl)amino)...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463555(2-(4-Fluorophenyl)-3-(4-(N-methylacetamido)piperid...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463556(2-(4-Fluorophenyl)-3-(4-methyl-3-oxopiperazin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463553(3-(Isopropyl(methyl)amino)-2-(5-methylthiophen-2-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463554(3-(Isopropyl(methyl)amino)-2-(thiophen-2-yl)quinox...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463499(2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-(isoprop...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463533(3-(Isopropyl(methyl)amino)-2-(4-(methylsulfonyl)ph...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463497(3-(3,3-Dimethylpiperidin-1-yl)-2-(4-fluorophenyl)q...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463498(2-(4-Fluorophenyl)-3-(3-methylpiperidin-1-yl)quino...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463534(3-(Isopropyl(methyl)amino)-2-(4-(trifluoromethoxy)...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463535(2-(4-Cyanophenyl)-3-(isopropyl(methyl)amino)quinox...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463500(2-(Benzo[d][1,3]dioxol-5-yl)-3-((S)-2-methylpyrrol...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463501(2-(1H-Indol-5-yl)-3-(isopropyl(methyl)amino)quinox...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463504(2-(Benzofuran-2-yl)-3-(isopropyl(methyl)amino)quin...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463536((S)-2-(4-Fluorophenyl)-3-(2-methyl-4-(pyridin-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463502(3-(Isopropyl(methyl)amino)-2-(pyridin-4-yl)quinoxa...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463503(2-(H-Imidazo[1,2-a]pyridin-6-yl)-3-(isopropyl(meth...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463539(US10781185, Example 93 | (R)-2-(4-Fluorophenyl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463540(US10781185, Example 94 | (S)-3-(2-Methyl-4-(pyridi...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463537((S)-2-(4-Fluorophenyl)-3-(2-methylpiperidin-1-yl)q...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463538(US10781185, Example 92 | 3-(Cyclopropyl(methyl)ami...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463454(2-(Azepan-1-yl)-3-phenylquinoxaline-6-carboxylic a...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463455(3-Phenyl-2-(piperidin-1-yl)quinoxaline-6-carboxyli...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463452(2-Phenyl-3-(4-(5-(trifluoromethyl)pyridin-2-yl)pip...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463453(2-phenyl-3-(4-(quinolin-2-yl)piperazin-1-yl)quinox...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463458(3-(4-Fluorophenyl)-2-(4-(4-methoxyphenyl)piperidin...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463459(3-(4-Fluorophenyl)-2-(4-(pyridin-2-yl)piperazin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463456(2-(4-(4-Chlorophenyl)piperidin-1-yl)-3-(4-fluoroph...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463457(2-(4-(3-Chlorophenyl)piperidin-1-yl)-3-(4-fluoroph...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM574760(US11459307, Example 30 | 2,3-Bis(4-phenylpiperidin...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463463(2,3-Bis(4-methoxyphenyl)-6-(1H-tetrazol-5-yl)quino...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463460(2-Phenyl-3-(4-(3-(trifluoromethyl)pyridin-2-yl)pip...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463461(3-(4-Fluorophenyl)-2-(4-(4-(trifluoromethyl)phenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463466(3-(4-(3-Chlorophenyl)piperazin-1-yl)-2-phenylquino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463467(3-(4-Methylpiperazin-1-yl)-2-phenylquinoxaline-6-c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463464(2-Phenyl-3-(4-(4-(trifluoromethyl)phenyl)piperazin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463465(2-Phenyl-3-(4-(pyridin-2-yl)piperazin-1-yl)quinoxa...)
Affinity DataIC50: 1.00E+4nMAssay Description:Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463442(3-(4-(4-Methoxyphenyl)piperidin-1-yl)-2-phenylquin...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

LigandPNGBDBM463450(3-(Isopropylamino)-2-phenylquinoxaline-6-carboxyli...)
Affinity DataIC50: 1.00E+4nMAssay Description:One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

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