Compile Data Set for Download or QSAR
Report error Found 395 Enz. Inhib. hit(s) with all data for entry = 11109
LigandChemical structure of BindingDB Monomer ID 591155BDBM591155(US11566003, Compound 111)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591244BDBM591244((S)-2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591211BDBM591211(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591250BDBM591250(2'-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-f...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591217BDBM591217(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591249BDBM591249(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591222BDBM591222(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591220BDBM591220(2-((8-amino-6-(5-amino-4-ethylpyridin- 3-yl)-7-flu...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591252BDBM591252(2-((8-amino-7-fluoro-6-(4-methyl-6- (oxazol-2-yl)p...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591225BDBM591225(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591137BDBM591137(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7- f...)
Affinity DataKi:  0.0130nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591137BDBM591137(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7- f...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591144BDBM591144((1R,2S,3R)-N-(8-amino-7-fluoro-6-(8-methyl-2,3-dih...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591146BDBM591146(US11566003, Compound 35)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591242BDBM591242(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591240BDBM591240(2-((8-amino-6-(5-amino-4- chloropyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591143BDBM591143(1-(8-amino-7-fluoro-6-(8-methyl- 2,3-dihydro-1H-py...)
Affinity DataKi:  0.0140nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591147BDBM591147(US11566003, Compound 36)
Affinity DataKi:  0.0140nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591246BDBM591246(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0150nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591136BDBM591136(2'-((8-amino-7-fluoro-6-(4- methylpyridin-3-yl)iso...)
Affinity DataKi:  0.0150nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591136BDBM591136(2'-((8-amino-7-fluoro-6-(4- methylpyridin-3-yl)iso...)
Affinity DataKi:  0.0150nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591139BDBM591139(US11566003, Compound 9)
Affinity DataKi:  0.0160nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591141BDBM591141(US11566003, Compound 11)
Affinity DataKi:  0.0160nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591177BDBM591177(2-((8-amino-6-(5-amino-4- chloropyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0160nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591243BDBM591243((R)-2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-...)
Affinity DataKi:  0.0170nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591233BDBM591233(2-((8-amino-6-(5-amino-4,6- dimethylpyridin-3-yl)-...)
Affinity DataKi:  0.0170nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591232BDBM591232(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0170nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591167BDBM591167(2-((8-amino-7-fluoro-6-(8-methyl-2,3- dihydro-1H-p...)
Affinity DataKi:  0.0180nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591239BDBM591239(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0190nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591148BDBM591148(tetrahydro-2H-pyran-4-yl (8-amino- 6-(5-amino-4-me...)
Affinity DataKi:  0.0200nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591273BDBM591273(US11566003, Compound 340)
Affinity DataKi:  0.0200nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591272BDBM591272(US11566003, Compound 339)
Affinity DataKi:  0.0200nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591168BDBM591168(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0210nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591169BDBM591169(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0240nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591237BDBM591237((E)-2-((8-amino-7-fluoro-6-(4- methylpyridin-3-yl)...)
Affinity DataKi:  0.0240nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591145BDBM591145(US11566003, Compound 34)
Affinity DataKi:  0.0250nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591213BDBM591213(US11566003, Compound 279)
Affinity DataKi:  0.0260nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591291BDBM591291(US11566003, Compound 358)
Affinity DataKi:  0.0260nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591290BDBM591290(US11566003, Compound 357)
Affinity DataKi:  0.0260nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591294BDBM591294((S)-2-((8-amino-7-fluoro-6-(4- methylpyridin-3-yl)...)
Affinity DataKi:  0.0330nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591295BDBM591295((R)-2-((8-amino-7-fluoro-6-(4- methylpyridin-3-yl)...)
Affinity DataKi:  0.0340nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591180BDBM591180(2-((8-amino-6-(5-amino-4- methoxypyridin-3-yl)-7- ...)
Affinity DataKi:  0.0350nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591321BDBM591321(6-(8-amino-7-fluoro-3-((6-methyl-7- oxo-5,6,7,8-te...)
Affinity DataKi:  0.0380nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591117BDBM591117(trans-N-(8-amino-6-(5-amino-4- methylpyridin-3-yl)...)
Affinity DataKi:  0.0410nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591251BDBM591251(2-((8-amino-7-fluoro-6-(4- methylpyridin-3-yl)isoq...)
Affinity DataKi:  0.0430nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591041BDBM591041(trans-N-(8-amino-6-((S)-4-methyl-2- oxooxazolidin-...)
Affinity DataKi:  0.0520nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591142BDBM591142((1R,2S,3R)-N-(8-amino-7-fluoro-6-(8-methyl-2,3-dih...)
Affinity DataKi:  0.0540nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591122BDBM591122(US11566003, Compound 214)
Affinity DataKi:  0.0560nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591135BDBM591135(2-((8-amino-7-fluoro-6-(4- methylpyridin-3-yl)isoq...)
Affinity DataKi:  0.0780nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 591135BDBM591135(2-((8-amino-7-fluoro-6-(4- methylpyridin-3-yl)isoq...)
Affinity DataKi:  0.0790nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

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