Compile Data Set for Download or QSAR
Report error Found 468 Enz. Inhib. hit(s) with all data for entry = 11123
LigandChemical structure of BindingDB Monomer ID 592760BDBM592760(US11572374, Example 12-6 | 2-chloro-N-(8-cyano-8- ...)
Affinity DataIC50: 10nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592741BDBM592741(US11572374, Example 7-3 | (3S)-6-chloro-N-((1R,2R,...)
Affinity DataIC50: 17nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592645BDBM592645((3S)-6-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[...)
Affinity DataIC50: 20nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592753BDBM592753(US11572374, Example 7-15 | 1-((1R,2R,4S)-7-cyano-7...)
Affinity DataIC50: 22nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592927BDBM592927(US11572374, Example 30-7 | (3S)-1-(3-chloro-5-meth...)
Affinity DataIC50: 25nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592951BDBM592951(US11572374, Example 12-2-3)
Affinity DataIC50: 25nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592779BDBM592779(US11572374, Example 12-25 | (3E)-N-((1R,2R,4S)-7-c...)
Affinity DataIC50: 26nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592826BDBM592826(US11572374, Example 20-14 | 3-chloro-N-((1R,2R,4S)...)
Affinity DataIC50: 26nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592654BDBM592654(6-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50: 26nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592735BDBM592735(US11572374, Example 2-63 | 3-chloro-N-((1R,2R,4S)-...)
Affinity DataIC50: 27nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592861BDBM592861(US11572374, Example 20-49 | 2-chloro-N-((1R,2R,4S)...)
Affinity DataIC50: 27nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592819BDBM592819(US11572374, Example 20-7 | 3-chloro-N-((1R,2R,4S)-...)
Affinity DataIC50: 28nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592920BDBM592920(US11572374, Example 29-7 | (3S)-1-(3-chloro-6-(tri...)
Affinity DataIC50: 29nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592926BDBM592926(US11572374, Example 30-6 | (3S)-1-(3-chloro-5-(tri...)
Affinity DataIC50: 29nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592827BDBM592827(US11572374, Example 20-15 | 3-chloro-N-((1R,2R,4S)...)
Affinity DataIC50: 30nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592697BDBM592697(2-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50: 31nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592775BDBM592775(US11572374, Example 12-21 | (3E)-N-((1R,2R,4S)-7-c...)
Affinity DataIC50: 34nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592755BDBM592755(US11572374, Example 7-17 | 2-chloro-N-((1R,2R,4S)-...)
Affinity DataIC50: 37nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592924BDBM592924(US11572374, Example 30-4 | (3S)-N-((1R,2R,4S)-7-cy...)
Affinity DataIC50: 37nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592781BDBM592781(US11572374, Example 12-27 | (2E)-3-(5-chloro-1-ben...)
Affinity DataIC50: 38nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592839BDBM592839(US11572374, Example 20-27 | N-((1R,2R,4S)-7-cyano-...)
Affinity DataIC50: 39nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592778BDBM592778(US11572374, Example 12-24 | (2E)-3-(5-chloro-1-eth...)
Affinity DataIC50: 40nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592837BDBM592837(US11572374, Example 20-25 | 3-chloro-N-((1R,2R,4S)...)
Affinity DataIC50: 41nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592782BDBM592782(US11572374, Example 12-28 | 3'-bromo-N-((1R,2R,4S)...)
Affinity DataIC50: 44nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592940BDBM592940(US11572374, Example 32-1 | (3S)-1-(3-chloro-5-cyan...)
Affinity DataIC50: 44nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592912BDBM592912(US11572374, Example 28-1 | (3S)-N-((1R,2R,4S)-7-cy...)
Affinity DataIC50: 46nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592714BDBM592714(US11572374, Example 2-42 | 2-chloro-N-((1R,2R,4S)-...)
Affinity DataIC50: 46nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592822BDBM592822(US11572374, Example 20-10 | 3-chloro-N-((1R,2R,4S)...)
Affinity DataIC50: 47nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592805BDBM592805(US11572374, Example 15-12-2 | (1S,4R,5S)-N-((1R,2R...)
Affinity DataIC50: 48nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592829BDBM592829(US11572374, Example 20-17 | 3-chloro-N-((1R,2R,4S)...)
Affinity DataIC50: 49nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592968BDBM592968(US11572374, Example 20-77 | N-((1R,2R,4S)-7-cyano-...)
Affinity DataIC50: 50nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592886BDBM592886(US11572374, Example 20-74 | N-((1R,2R,4S)-7-cyano-...)
Affinity DataIC50: 50nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592777BDBM592777(US11572374, Example 12-23 | (3E)-4-(3-chlorophenyl...)
Affinity DataIC50: 54nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592937BDBM592937(US11572374, Example 30-17 | (3S)-N-((1R,2R,4S)-7-c...)
Affinity DataIC50: 54nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592913BDBM592913(US11572374, Example 28-2 | (3S)-1-(5-chloro-2-cyan...)
Affinity DataIC50: 54nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592818BDBM592818(US11572374, Example 20-6 | 3,4'-dichloro-N-((1R,2R...)
Affinity DataIC50: 55nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592816BDBM592816(US11572374, Example 20-4 | 3,3'-dichloro-N-((1R,2R...)
Affinity DataIC50: 55nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592765BDBM592765(US11572374, Example 12-11 | N-((1R,2R,4S)-7-cyano-...)
Affinity DataIC50: 56nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592808BDBM592808(US11572374, Example 15-15 | 6-chloro-N-((1R,2R,4S)...)
Affinity DataIC50: 57nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592759BDBM592759(US11572374, Example 12-5 | 6-(((1-(4- bromophenyl)...)
Affinity DataIC50: 57nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592880BDBM592880(US11572374, Example 20-68 | N-((1R,2R,4S)-7-cyano-...)
Affinity DataIC50: 58nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592918BDBM592918(US11572374, Example 29-5 | (3S)-N-((1R,2R,4S)-7-cy...)
Affinity DataIC50: 58nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592815BDBM592815(US11572374, Example 20-3 | 2',3-dichloro-N-((1R,2R...)
Affinity DataIC50: 60nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592674BDBM592674(2-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50: 61nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592694BDBM592694(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50: 62nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592947BDBM592947(US11572374, Example 33-1-2 | (1R,4R,5R)-N-((1R,2R,...)
Affinity DataIC50: 62nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592934BDBM592934(US11572374, Example 30-14 | (3S)-N-((1R,2R,4S)-7-c...)
Affinity DataIC50: 62nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592764BDBM592764(US11572374, Example 12-10 | US11572374, Example 12...)
Affinity DataIC50: 64nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592742BDBM592742(US11572374, Example 7-4 | N-((1R,2R,4S)-7-cyano-7-...)
Affinity DataIC50: 64nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 592944BDBM592944(US11572374, Example 32-5 | (3S)-N-((1R,2R,4S)-7-cy...)
Affinity DataIC50: 64nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

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