Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 11209
TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600613BDBM600613(US11629146, Compound 98 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600612BDBM600612(US11629146, Compound 62 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600617BDBM600617(US11629146, Compound 70 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600616BDBM600616(US11629146, Compound 48 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600615BDBM600615(US11629146, Compound 76 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600614BDBM600614(US11629146, Compound 1 | US20250163068, Compound 1)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600621BDBM600621(US11629146, Compound 122)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600620BDBM600620(US11629146, Compound 97)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600619BDBM600619(US11629146, Compound 79 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600618BDBM600618(US11629146, Compound 116 | US20250163068, Compound...)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600625BDBM600625(US11629146, Compound 47)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600624BDBM600624(US11629146, Compound 56 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600623BDBM600623(US11629146, Compound 118 | US20250163068, Compound...)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600622BDBM600622(US11629146, Compound 41)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600684BDBM600684(US11629146, Compound 136 | US20250163068, Compound...)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600683BDBM600683(US11629146, Compound 84)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 50173494BDBM50173494(CHEMBL3810347 | US11629146, Compound 108 | US20250...)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600673BDBM600673(US11629146, Compound 52 | US20250163068, Compound ...)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600672BDBM600672(US11629146, Compound 46)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600671BDBM600671(US11629146, Compound 112)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600678BDBM600678(US11629146, Compound 6 | US20250163068, Compound 6)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600677BDBM600677(US11629146, Compound 72 | US20250163068, Compound ...)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600676BDBM600676(US11629146, Compound 73 | US20250163068, Compound ...)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600675BDBM600675(US11629146, Compound 113)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600682BDBM600682(US11629146, Compound 77 | US20250163068, Compound ...)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600681BDBM600681(US11629146, Compound 66 | US20250163068, Compound ...)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600680BDBM600680(US11629146, Compound 12 | US20250163068, Compound ...)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600679BDBM600679(US11629146, Compound 3 | US20250163068, Compound 3)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600686BDBM600686(US11629146, Compound 49 | US20250163068, Compound ...)
Affinity DataIC50: 2.25E+4nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600685BDBM600685(US11629146, Compound 117 | US20250163068, Compound...)
Affinity DataIC50: 2.25E+4nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600689BDBM600689(US11629146, Compound 30 | US20250163068, Compound ...)
Affinity DataIC50: 2.25E+4nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600688BDBM600688(US11629146, Compound 105)
Affinity DataIC50: 2.25E+4nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600687BDBM600687(US11629146, Compound 63 | US20250163068, Compound ...)
Affinity DataIC50: 2.25E+4nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600690BDBM600690(US11629146, Compound 135 | US11629146, Compound 13...)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600694BDBM600694(US11629146, Compound 96 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600693BDBM600693(US11629146, Compound 124 | US20250163068, Compound...)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600692BDBM600692(US11629146, Compound 125 | US20250163068, Compound...)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600691BDBM600691(US11629146, Compound 126 | US20250163068, Compound...)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600698BDBM600698(US11629146, Compound 127)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600697BDBM600697(US11629146, Compound 107)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600696BDBM600696(US11629146, Compound 42)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600695BDBM600695(US11629146, Compound 78 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600702BDBM600702(US11629146, Compound 59 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600701BDBM600701(US11629146, Compound 43)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600700BDBM600700(US11629146, Compound 65 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600690BDBM600690(US11629146, Compound 135 | US11629146, Compound 13...)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600703BDBM600703(US11629146, Compound 68 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent