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Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 11215
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510506BDBM510506(6-(2-chlorophenyl)-4-[(3R)-3-methylmorpholin-4-yl]...)
Affinity DataIC50: 7nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510507BDBM510507(4-[(3R)-3-methylmorpholin-4-yl]-6-[2-(trifluoromet...)
Affinity DataIC50: 7nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510503BDBM510503(6-(2-chloro-5-fluoro-phenyl)-4-[(3R)-3-methylmorph...)
Affinity DataIC50: 10nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510498BDBM510498(6-(2-chlorophenyl)-4-(3-methylmorpholin-4-yl)-1H-p...)
Affinity DataIC50: 10nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510499BDBM510499(US11077113, Example 4 | BDBM600779 | 6-(2-chloroph...)
Affinity DataIC50: 20nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510505BDBM510505(4-[(3R)-3-methylmorpholin-4-yl]-6-[2-(trifluoromet...)
Affinity DataIC50: 20nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510504BDBM510504(4-[(3R)-3-methylmorpholin-4-yl]-6-(o-tolyl)-1H-pyr...)
Affinity DataIC50: 30nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510509BDBM510509(4-[(3R)-3-methylmorpholin-4-yl]-6-(4-methyl-3-thie...)
Affinity DataIC50: 30nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510495BDBM510495(6-(2-chlorophenyl)-4-morpholino-1H-pyridin-2-one |...)
Affinity DataIC50: 30nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510497BDBM510497(6-(2-chlorophenyl)-1-methyl-4-morpholino-pyridin-2...)
Affinity DataIC50: 50nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510502BDBM510502(4-(3-methylmorpholin-4-yl)-6-(2-phenylphenyl)-1H-p...)
Affinity DataIC50: 60nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510500BDBM510500(4-(3-methylmorpholin-4-yl)-6-(4-methyl-3-pyridyl)-...)
Affinity DataIC50: 100nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510510BDBM510510(N-[2-[4-[(3R)-3-methylmorpholin-4-yl]-6-oxo-1H-pyr...)
Affinity DataIC50: 200nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510508BDBM510508(6-(3-furyl)-4-[(3R)-3-methylmorpholin-4-yl]-1H-pyr...)
Affinity DataIC50: 200nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510512BDBM510512(4-[(3R)-3-methylmorpholin-4-yl]-6-[4-(1H-pyrazol-5...)
Affinity DataIC50: 200nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510511BDBM510511(4-[(3R)-3-methylmorpholin-4-yl]-6-(6-methyl-5-quin...)
Affinity DataIC50: 200nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 510501BDBM510501(4-(3-methylmorpholin-4-yl)-6-pyrimidin-5-yl-1H-pyr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent