Compile Data Set for Download or QSAR
Report error Found 255 Enz. Inhib. hit(s) with all data for entry = 11217
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601043BDBM601043(4-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1H-tria...)
Affinity DataIC50: 2.90nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601048BDBM601048(2-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1,3,4-o...)
Affinity DataIC50: 3nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600981BDBM600981(2-(2,4-dichloro-3-(trifluoromethyl)phenyl)-5-(meth...)
Affinity DataIC50: 3.60nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600982BDBM600982(2-(2,4-dichloro-3-(trifluoromethyl)phenyl)-5-ethox...)
Affinity DataIC50: 4.30nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601045BDBM601045(4,5-dideuterio-1-[2,4-dichloro-3-(trifluoromethyl)...)
Affinity DataIC50: 4.40nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601001BDBM601001(5-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1,3,4-o...)
Affinity DataIC50: 5.70nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600981BDBM600981(2-(2,4-dichloro-3-(trifluoromethyl)phenyl)-5-(meth...)
Affinity DataIC50: 5.80nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601033BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
Affinity DataIC50: 6.10nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600986BDBM600986(N-(5-(2,4-dichloro-3-(trifluoromethyl)phenyl)-1,3,...)
Affinity DataIC50: 7.30nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600827BDBM600827(4-(3,4-bis(trifluoromethyl)phenyl)-1H-1,2,3-triazo...)
Affinity DataIC50: 8nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601044BDBM601044(3,5-dichloro-2-(triazol-1-yl)-4-(trifluoromethyl)p...)
Affinity DataIC50: 8.10nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601015BDBM601015([1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazol...)
Affinity DataIC50: 9.60nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600928BDBM600928(5-(7-chloro-1,3,3-trimethyl-indolin-5-yl)-1,3,4-ox...)
Affinity DataIC50: 10.3nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600988BDBM600988(5-(2,4-dichloro-3-(trifluoromethyl)phenyl)-1,3,4-o...)
Affinity DataIC50: 11.9nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600941BDBM600941(2-[4-cyclopropyl-3-(trifluoromethyl)phenyl]-1,3,4-...)
Affinity DataIC50: 12nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600998BDBM600998(5-(4-bromo-3-(trifluoromethyl)phenyl)-1,3,4-oxadia...)
Affinity DataIC50: 12nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600990BDBM600990(5-(8-chlorochroman-6-yl)-1,3,4-oxadiazol-2-ol | US...)
Affinity DataIC50: 12.9nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600893BDBM600893((5-(4-chloro-3-(trifluoromethyl)phenyl)isoxazol-3-...)
Affinity DataIC50: 13nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600845BDBM600845(5-(4-chloro-3-(trifluoromethoxy)phenyl)-1,3,4-oxad...)
Affinity DataIC50: 14.3nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 50554450BDBM50554450(CHEMBL4760228 | US11634391, Compound 196)
Affinity DataIC50: 16.6nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601028BDBM601028(1-(2,3,4-trichlorophenyl)triazole | US11634391, Co...)
Affinity DataIC50: 16.7nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600849BDBM600849(5-(4-cyclopentylphenyl)-1,3,4-oxadiazol-2-ol | US1...)
Affinity DataIC50: 19nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600872BDBM600872(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-ol | US11...)
Affinity DataIC50: 19.1nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600828BDBM600828(4-(4-chloro-3-(trifluoromethyl)phenyl)-1H-1,2,3-tr...)
Affinity DataIC50: 19.4nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600844BDBM600844(5-(4-chloro-3-(trifluoromethyl)phenyl)-1,3,4-oxadi...)
Affinity DataIC50: 20.1nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600868BDBM600868(5-(2-naphthyl)-1,3,4-oxadiazol-2-ol | US11634391, ...)
Affinity DataIC50: 20.1nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600992BDBM600992(5-(7-chloro-3,3-dimethyl-2,3-dihydrobenzofuran-5-y...)
Affinity DataIC50: 20.3nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600861BDBM600861(5-(3-methyl-5-(trifluoromethyl)phenyl)-1,3,4-oxadi...)
Affinity DataIC50: 22.7nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601007BDBM601007(5-[4-(3-fluoroazetidin-1-yl)-3-(trifluoromethyl)ph...)
Affinity DataIC50: 24.7nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601036BDBM601036(2-(2,4-dichloro-3-(trifluoromethyl)phenyl)-5-methy...)
Affinity DataIC50: 27nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600999BDBM600999(5-(3-(pyrrolidin-1-yl)-4-(trifluoromethyl)phenyl)-...)
Affinity DataIC50: 27.1nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601041BDBM601041(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
Affinity DataIC50: 30.3nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600940BDBM600940(5-[4-cyclopropyl-3-(trifluoromethyl)phenyl]-1,3,4-...)
Affinity DataIC50: 30.7nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601004BDBM601004(5-[4-pyrrolidin-1-yl-3-(trifluoromethyl)phenyl]-1,...)
Affinity DataIC50: 31.4nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600938BDBM600938(2-[3-cyclopropyl-4-(trifluoromethyl)phenyl]-1,3,4-...)
Affinity DataIC50: 31.6nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600862BDBM600862(5-(4-methyl-3-(trifluoromethyl)phenyl)-1,3,4-oxadi...)
Affinity DataIC50: 31.7nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600989BDBM600989(5-(2,4-dichloro-3-(trifluoromethyl)phenyl)-N-methy...)
Affinity DataIC50: 31.9nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600876BDBM600876(5-(4-cyclopropylphenyl)-1,3,4-oxadiazol-2-ol | US1...)
Affinity DataIC50: 32.6nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600929BDBM600929(5-(1,3,3-trimethylindolin-5-yl)-1,3,4-oxadiazol-2-...)
Affinity DataIC50: 34.4nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600932BDBM600932(5-[4-chloro-3-(trifluoromethyl)phenyl]-1,3,4-thiad...)
Affinity DataIC50: 35.4nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600855BDBM600855(5-(4-methyl-3-(trifluoromethoxy)phenyl)-1,3,4-oxad...)
Affinity DataIC50: 36nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601002BDBM601002(5-[2-methyl-3-(trifluoromethyl)phenyl]-1,3,4-oxadi...)
Affinity DataIC50: 36.7nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600942BDBM600942(5-[3-cyclopropyl-4-(trifluoromethyl)phenyl]-1,3,4-...)
Affinity DataIC50: 42.1nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600863BDBM600863(5-(3-chloro-5-(trifluoromethyl)phenyl)-1,3,4-oxadi...)
Affinity DataIC50: 45.9nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601030BDBM601030(1-(3,4,5-trichlorophenyl)triazole | US11634391, Co...)
Affinity DataIC50: 46nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600944BDBM600944(5-(4-cyclopropyl-3-methyl-phenyl)-1,3,4-oxadiazol-...)
Affinity DataIC50: 49.1nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600946BDBM600946(5-(7-chloro-1-methyl-indolin-5-yl)-1,3,4-oxadiazol...)
Affinity DataIC50: 49.9nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601006BDBM601006(5-[4-(3,3-difluoroazetidin-1-yl)-3-(trifluoromethy...)
Affinity DataIC50: 65.1nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 601021BDBM601021(2-[4-(3-fluoroazetidin-1-yl)-3-(trifluoromethyl)ph...)
Affinity DataIC50: 66.1nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandChemical structure of BindingDB Monomer ID 600985BDBM600985(5-(2,4-dichloro-3-(trifluoromethyl)phenyl)-3-methy...)
Affinity DataIC50: 67nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

Displayed 1 to 50 (of 255 total ) | Next | Last >>
Jump to: