Compile Data Set for Download or QSAR
Report error Found 129 Enz. Inhib. hit(s) with all data for entry = 11227
TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601556(2-(2,4- Difluorophenyl)-6- methyl-N-[(3S)-2- oxo-5...)
Affinity DataEC50:  8nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601514(2-[6-(Cyclopropylamino)-2-fluoropyridin-3-yl]-N-[(...)
Affinity DataEC50:  13nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601532(2-[6- (Ethylamino)-2- fluoropyridin-3- yl]-N-[(3S)...)
Affinity DataEC50:  13nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601557(2-(2,4- Difluorophenyl)-N- [(3S)-9-fluoro-2-oxo- 5...)
Affinity DataEC50:  17nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601531(2-[6- (Ethylamino)-2- fluoropyridin-3- yl]-N-[(3S)...)
Affinity DataEC50:  18nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601476(2-[2-Fluoro-4- (methylamino)phe- nyl]-N-[(3S)-2-ox...)
Affinity DataEC50:  18nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601535(2-[2-Fluoro-6- (propan-2- ylamino)pyridin- 3-yl]-N...)
Affinity DataEC50:  19nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601555(2-(2,4- Difluorophenyl)-N- [(3S)-9-fluoro-2-oxo- 5...)
Affinity DataEC50:  19nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601554(2-(2,4- Difluorophenyl)-N- [(3S)-2-oxo-5- phenyl-1...)
Affinity DataEC50:  20nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601484(N-[(3S)-9- Fluoro-2-oxo-5- phenyl-1,3- dihydro-1,4...)
Affinity DataEC50:  21nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601500(N-[(3S)-9- Fluoro-2-oxo-5- phenyl-1,3- dihydro-1,4...)
Affinity DataEC50:  23nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601536(N-[(3S)-9-Fluoro- 2-oxo-5-phenyl- 1,3-dihydro-1,4-...)
Affinity DataEC50:  23nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601527(2-[2-Methyl-6- (propan-2- ylamino)pyridin- 3-yl]-N...)
Affinity DataEC50:  25nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601545(N-[(3S)-9-Fluoro-2-oxo- 5-phenyl-1,3-dihydro- 1,4-...)
Affinity DataEC50:  26nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601504(N-[(3S)-9- Fluoro-2-oxo-5- phenyl-1,3- dihydro-1,4...)
Affinity DataEC50:  27nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601584(6-Chloro-2-(6-ethylpyridin-3-yl)-N-[(3S)-9-fluoro-...)
Affinity DataEC50:  27nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601502(2-(2,4- Difluorophenyl)- N-[(3S)-9- fluoro-2-oxo-5...)
Affinity DataEC50:  27nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601540(N-[(3S)-9-Fluoro- 2-oxo-5-phenyl- 1,3-dihydro-1,4-...)
Affinity DataEC50:  28nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601478(N-[(3S)-9-fluoro-2-oxo-5-phenyl-1,3-dihydro-1,4-be...)
Affinity DataEC50:  28nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601586(N-[(3S)-9-fluoro- 2-oxo-5-phenyl- 1,3-dihydro-1,4-...)
Affinity DataEC50:  28nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601499(2-(2- Fluorophenyl)-6- methyl-N-[(3S)- 2-oxo-5-phe...)
Affinity DataEC50:  29nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601501(2-(2,4- Difluorophenyl)- 5-methyl-N- [(3S)-2-oxo-5...)
Affinity DataEC50:  29nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601570(6-Methyl-2-(6- morpholin-4- ylpyridin-3-yl)-N- [(3...)
Affinity DataEC50:  29nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601479(N-[(3S)-9-fluoro-2-oxo-5-phenyl-1,3-dihydro-1,4-be...)
Affinity DataEC50:  31nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601559(N-[(3S)-9-Fluoro-2- oxo-5-phenyl-1,3- dihydro-1,4-...)
Affinity DataEC50:  33nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601483(2-(2- Fluorophenyl)-5- methyl-N-[(3S)- 2-oxo-5-phe...)
Affinity DataEC50:  33nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601583(6-Chloro-N-[(3S)-9-fluoro-2-oxo-5-phenyl-1,3-dihyd...)
Affinity DataEC50:  33nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601582(N-[(3S)-9-fluoro-2-oxo-5-phenyl-1,3-dihydro-1,4-be...)
Affinity DataEC50:  34nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601457(2-[4-(Methylamino)phenyl]-N-[(3S)-2-oxo-5-phenyl-1...)
Affinity DataEC50:  35nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601573(N-[(3S)-9-fluoro-2- oxo-5-phenyl-1,3- dihydro-1,4-...)
Affinity DataEC50:  37nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601571(N-[(3S)-9-fluoro-2- oxo-5-phenyl-1,3- dihydro-1,4-...)
Affinity DataEC50:  38nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601458(2-(2-Fluorophenyl)-N- [(3S)-2-oxo-5-phenyl- 1,3-di...)
Affinity DataEC50:  39nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601503(2-(2- Fluorophenyl)-7- methyl-N-[(3S)- 2-oxo-5-phe...)
Affinity DataEC50:  39nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601461(2-(2,4-Difluorophenyl)- N-[(3S)-9-fluoro-2-oxo- 5-...)
Affinity DataEC50:  39nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601579(US11634425, Example 114 | N-[(3S)-9-fluoro- 2-oxo-...)
Affinity DataEC50:  39nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601473(2-(2-Fluoro-4- methoxyphenyl)-N- [(3S)-2-oxo-5- ph...)
Affinity DataEC50:  41nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601526(2-[2-Methyl-6- (propan-2- ylamino)pyridin- 3-yl]-N...)
Affinity DataEC50:  41nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601494(2-(5-Chloropyridin-3- yl)-N-[(3S)-9-fluoro-2- oxo-...)
Affinity DataEC50:  41nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601579(US11634425, Example 114 | N-[(3S)-9-fluoro- 2-oxo-...)
Affinity DataEC50:  41nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601508(2-(2,3-Difluorophenyl)-N-[(3S)-9-fluoro-2-oxo-5-ph...)
Affinity DataEC50:  41nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601590(US11634425, Example 123 | 2-(6-Ethylpyridin-3-yl)-...)
Affinity DataEC50:  42nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601541(N-[(3S)-9-Fluoro- 2-oxo-5-phenyl- 1,3-dihydro-1,4-...)
Affinity DataEC50:  44nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601590(US11634425, Example 123 | 2-(6-Ethylpyridin-3-yl)-...)
Affinity DataEC50:  45nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601539(N-[(3S)-2-oxo-5- phenyl-1,3- dihydro-1,4- benzodia...)
Affinity DataEC50:  45nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601521(2-(6-Ethylpyridin- 3-yl)-N-[(3S)-9- fluoro-2-oxo-5...)
Affinity DataEC50:  45nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601566(N-[(3S)-9-fluoro-2- oxo-5-phenyl-1,3- dihydro-1,4-...)
Affinity DataEC50:  47nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601558(6-Methyl-N-[(3S)-2- oxo-5-phenyl-1,3- dihydro-1,4-...)
Affinity DataEC50:  48nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601577(6-Methoxy-N-[(3S)-2-oxo-5-phenyl-1,3-dihydro-1,4-b...)
Affinity DataEC50:  48nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601564(N-[(3S)-9-fluoro-2- oxo-5-phenyl-1,3- dihydro-1,4-...)
Affinity DataEC50:  48nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601563(6-Methyl-2-(2- methylpyridin-4-yl)- N-[(3S)-2-oxo-...)
Affinity DataEC50:  49nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

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