Compile Data Set for Download or QSAR
Report error Found 218 Enz. Inhib. hit(s) with all data for entry = 11326
TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607734BDBM607734(US11691962, Compound 1-132)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607732BDBM607732(US11691962, Compound 1-130)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607731BDBM607731(US11691962, Compound 1-129)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607738BDBM607738(US11691962, Compound 1-136)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607737BDBM607737(US11691962, Compound 1-135)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607736BDBM607736(US11691962, Compound 1-134)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607742BDBM607742(US11691962, Compound 1-140)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607740BDBM607740(US11691962, Compound 1-138)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607739BDBM607739(US11691962, Compound 1-137)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607746BDBM607746(US11691962, Compound 1-144)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607745BDBM607745(US11691962, Compound 1-143)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607744BDBM607744(US11691962, Compound 1-142)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607743BDBM607743(US11691962, Compound 1-141)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607718BDBM607718(US11691962, Compound 1-116)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607717BDBM607717(US11691962, Compound 1-115)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607716BDBM607716(US11691962, Compound 1-114)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607715BDBM607715(US11691962, Compound 1-113)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607722BDBM607722(US11691962, Compound 1-120)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607721BDBM607721(US11691962, Compound 1-119)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607720BDBM607720(US11691962, Compound 1-118)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607719BDBM607719(US11691962, Compound 1-117)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607726BDBM607726(US11691962, Compound 1-124)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607725BDBM607725(US11691962, Compound 1-123)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607730BDBM607730(US11691962, Compound 1-128)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607729BDBM607729(US11691962, Compound 1-127)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607727BDBM607727(US11691962, Compound 1-125)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607766BDBM607766(US11691962, Compound 1-164)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607765BDBM607765(US11691962, Compound 1-163)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607764BDBM607764(US11691962, Compound 1-162)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607763BDBM607763(US11691962, Compound 1-161)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607770BDBM607770(US11691962, Compound 1-168)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607769BDBM607769(US11691962, Compound 1-167)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607768BDBM607768(US11691962, Compound 1-166)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607774BDBM607774(US11691962, Compound 1-172)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607777BDBM607777(US11691962, Compound 1-175)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607749BDBM607749(US11691962, Compound 1-147)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607748BDBM607748(US11691962, Compound 1-146)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607747BDBM607747(US11691962, Compound 1-145)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607754BDBM607754(US11691962, Compound 1-152)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607753BDBM607753(US11691962, Compound 1-151)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607752BDBM607752(US11691962, Compound 1-150)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607758BDBM607758(US11691962, Compound 1-156)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607757BDBM607757(US11691962, Compound 1-155)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607756BDBM607756(US11691962, Compound 1-154)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607755BDBM607755(US11691962, Compound 1-153)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607762BDBM607762(US11691962, Compound 1-160)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607761BDBM607761(US11691962, Compound 1-159)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607760BDBM607760(US11691962, Compound 1-158)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607798BDBM607798(US11691962, Compound 1-196)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Exithera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 607797BDBM607797(US11691962, Compound 1-195)
Affinity DataIC50: 10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

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