Compile Data Set for Download or QSAR
Report error Found 195 Enz. Inhib. hit(s) with all data for entry = 11350
TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 609011BDBM609011(US11702409, Example 80a | US11702409, Example 80b)
Affinity DataIC50: 8nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 50579992BDBM50579992(CHEMBL5080264 | US11702409, Example 69b)
Affinity DataIC50: 9nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608941BDBM608941(US11702409, Example 43a | US11702409, Example 43b)
Affinity DataIC50: 10nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608937BDBM608937(US11702409, Example 41a | US11702409, Example 41b ...)
Affinity DataIC50: 11nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608859BDBM608859(US11702409, Example 16a | US11702409, Example 16b)
Affinity DataIC50: 11nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608939BDBM608939(US11702409, Example 42a | US11702409, Example 42b)
Affinity DataIC50: 12nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 609015BDBM609015(US11702409, Example 82a | US11702409, Example 82b)
Affinity DataIC50: 12nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608864BDBM608864(US11702409, Example 17a | US11702409, Example 17b)
Affinity DataIC50: 13nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 50579987BDBM50579987(CHEMBL5083497 | US11702409, Example 18b)
Affinity DataIC50: 14nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 609006BDBM609006(US11702409, Example 76a | US11702409, Example 76b)
Affinity DataIC50: 15nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608857BDBM608857(US11702409, Example 15a | US11702409, Example 15b)
Affinity DataIC50: 16nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 50579985BDBM50579985(Jdq 443 | Jdq-443 | Nvp-jdq-443 | JDQ443 | JDQ-443...)
Affinity DataIC50: 17nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608852BDBM608852(US11702409, Example 13a | US11702409, Example 13b)
Affinity DataIC50: 18nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 609017BDBM609017(US11702409, Example 83a | US11702409, Example 83b)
Affinity DataIC50: 18nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608943BDBM608943(US11702409, Example 44a | US11702409, Example 44b)
Affinity DataIC50: 19nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608876BDBM608876(US11702409, Example 22a | US11702409, Example 22b)
Affinity DataIC50: 23nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608850BDBM608850(US11702409, Example 12a | US11702409, Example 12b)
Affinity DataIC50: 24nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 50579990BDBM50579990(CHEMBL5081366 | US11702409, Example 52b)
Affinity DataIC50: 26nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 50579988BDBM50579988(CHEMBL5075960 | US11702409, Example 35b)
Affinity DataIC50: 27nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608976BDBM608976(US11702409, Example 61a | US11702409, Example 61b)
Affinity DataIC50: 27nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608994BDBM608994(US11702409, Example 70a | US11702409, Example 70b)
Affinity DataIC50: 30nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608933BDBM608933(US11702409, Example 39a | US11702409, Example 39b)
Affinity DataIC50: 32nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608968BDBM608968(US11702409, Example 57a | US11702409, Example 57b)
Affinity DataIC50: 33nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608955BDBM608955(US11702409, Example 50a | US11702409, Example 50b)
Affinity DataIC50: 35nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 50579991BDBM50579991(CHEMBL5078639 | US11702409, Example 56b)
Affinity DataIC50: 38nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608882BDBM608882(US11702409, Example 25a | US11702409, Example 25b)
Affinity DataIC50: 41nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608886BDBM608886(US11702409, Example 26a | 1-{6-[(4M)-4-(5-Chloro-6...)
Affinity DataIC50: 43nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608832BDBM608832(US11702409, Example 5a | US11702409, Example 5b)
Affinity DataIC50: 43nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608949BDBM608949(US11702409, Example 47a | US11702409, Example 47b)
Affinity DataIC50: 43nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608978BDBM608978(US11702409, Example 62a | US11702409, Example 62b)
Affinity DataIC50: 45nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608984BDBM608984(US11702409, Example 65a | US11702409, Example 65b)
Affinity DataIC50: 46nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608952BDBM608952(US11702409, Example 48)
Affinity DataIC50: 49nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608974BDBM608974(US11702409, Example 60a | US11702409, Example 60b)
Affinity DataIC50: 51nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608982BDBM608982(US11702409, Example 64a | US11702409, Example 64b)
Affinity DataIC50: 55nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608990BDBM608990(US11702409, Example 68a | US11702409, Example 68b)
Affinity DataIC50: 59nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608872BDBM608872(US11702409, Example 21a | US11702409, Example 21b)
Affinity DataIC50: 60nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608970BDBM608970(US11702409, Example 58a | US11702409, Example 58b)
Affinity DataIC50: 64nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608838BDBM608838(US11702409, Example 8a | US11702409, Example 8b)
Affinity DataIC50: 66nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608880BDBM608880(US11702409, Example 24a | US11702409, Example 24b)
Affinity DataIC50: 71nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608980BDBM608980(US11702409, Example 63a | US11702409, Example 63b)
Affinity DataIC50: 88nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 609010BDBM609010(US11702409, Example 79a)
Affinity DataIC50: 92nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 50579986BDBM50579986(CHEMBL5076213 | US11702409, Example 2b)
Affinity DataIC50: 93nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608935BDBM608935(US11702409, Example 40a | US11702409, Example 40b)
Affinity DataIC50: 99nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608996BDBM608996(US11702409, Example 71a | US11702409, Example 71b)
Affinity DataIC50: 101nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608896BDBM608896(US11702409, Example 30a | US11702409, Example 30b)
Affinity DataIC50: 103nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 609013BDBM609013(US11702409, Example 81a | US11702409, Example 81b)
Affinity DataIC50: 110nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608928BDBM608928(US11702409, Example 37a | US11702409, Example 37b)
Affinity DataIC50: 112nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608870BDBM608870(US11702409, Example 20a | US11702409, Example 20b)
Affinity DataIC50: 148nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608836BDBM608836(US11702409, Example 7a | US11702409, Example 7b)
Affinity DataIC50: 162nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 608972BDBM608972(US11702409, Example 59a | US11702409, Example 59b)
Affinity DataIC50: 173nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

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