Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 11398
TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611999BDBM611999(US11718619, Compound I-45)
Affinity DataEC50:  5.01nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611981BDBM611981(US11718619, Compound I-27)
Affinity DataEC50:  6.31nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 612002BDBM612002(US11718619, Compound I-48)
Affinity DataEC50:  6.31nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 612000BDBM612000(US11718619, Compound I-46)
Affinity DataEC50:  6.31nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611962BDBM611962(US11718619, Compound I-8)
Affinity DataEC50:  10nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611996BDBM611996(US11718619, Compound I-42)
Affinity DataEC50:  10nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 612003BDBM612003(US11718619, Compound I-49)
Affinity DataEC50:  10nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611978BDBM611978(US11718619, Compound I-24)
Affinity DataEC50:  12.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611998BDBM611998(US11718619, Compound I-44)
Affinity DataEC50:  12.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611963BDBM611963(US11718619, Compound I-9)
Affinity DataEC50:  12.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 612001BDBM612001(US11718619, Compound I-47)
Affinity DataEC50:  15.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611989BDBM611989(US11718619, Compound I-35)
Affinity DataEC50:  15.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611960BDBM611960(US11718619, Compound I-6)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611991BDBM611991(US11718619, Compound I-37)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611995BDBM611995(US11718619, Compound I-41)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611956BDBM611956(US11718619, Compound I-2)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 612004BDBM612004(US11718619, Compound I-51)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611965BDBM611965(US11718619, Compound I-11)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611968BDBM611968(US11718619, Compound I-14)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611988BDBM611988(US11718619, Compound I-34)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611971BDBM611971(US11718619, Compound I-17)
Affinity DataEC50:  31.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611966BDBM611966(US11718619, Compound I-12)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611964BDBM611964(US11718619, Compound I-10)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611980BDBM611980(US11718619, Compound I-26)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 612012BDBM612012(US11718619, Compound I-59)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611970BDBM611970(US11718619, Compound I-16)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611986BDBM611986(US11718619, Compound I-32)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611969BDBM611969(US11718619, Compound I-15)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 612015BDBM612015(US11718619, Compound I-62)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611958BDBM611958(US11718619, Compound I-4)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611997BDBM611997(US11718619, Compound I-43)
Affinity DataEC50:  50.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611990BDBM611990(US11718619, Compound I-36)
Affinity DataEC50:  50.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 612005BDBM612005(US11718619, Compound I-52)
Affinity DataEC50:  50.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611994BDBM611994(US11718619, Compound I-40)
Affinity DataEC50:  63.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611979BDBM611979(US11718619, Compound I-25)
Affinity DataEC50:  63.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611973BDBM611973(US11718619, Compound I-19)
Affinity DataEC50:  63.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611961BDBM611961(US11718619, Compound I-7)
Affinity DataEC50:  79.4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611977BDBM611977(US11718619, Compound I-23)
Affinity DataEC50:  79.4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 612014BDBM612014(US11718619, Compound I-61)
Affinity DataEC50:  79.4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 612013BDBM612013(US11718619, Compound I-60)
Affinity DataEC50:  100nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611959BDBM611959(US11718619, Compound I-5)
Affinity DataEC50:  126nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 612006BDBM612006(US11718619, Compound I-53)
Affinity DataEC50:  126nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611957BDBM611957(US11718619, Compound I-3)
Affinity DataEC50:  126nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611993BDBM611993(US11718619, Compound I-39)
Affinity DataEC50:  158nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611982BDBM611982(US11718619, Compound I-28)
Affinity DataEC50:  200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611967BDBM611967(US11718619, Compound I-13)
Affinity DataEC50:  200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611972BDBM611972(US11718619, Compound I-18)
Affinity DataEC50:  200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 612009BDBM612009(US11718619, Compound I-56)
Affinity DataEC50:  251nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611992BDBM611992(US11718619, Compound I-38)
Affinity DataEC50:  251nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandChemical structure of BindingDB Monomer ID 611985BDBM611985(US11718619, Compound I-31)
Affinity DataEC50:  251nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

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