Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 11931
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661982BDBM661982(4-(6-(4-methyl-3,4-dihydro-2H- benzo[b][1,4]oxazin...)
Affinity DataIC50: 5.67nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661975BDBM661975(2-fluoro-4-(6-(4-methyl-3,4-dihydro-2H- benzo[b][1...)
Affinity DataIC50: 8.01nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661978BDBM661978((S)-4-(6-(2,3-dihydrobenzo[b][1,4]dioxin- 6-yl)-3-...)
Affinity DataIC50: 9.57nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661974BDBM661974(4-(3-(azepan-4-ylmethyl)-6-(4-methyl-3,4- dihydro-...)
Affinity DataIC50: 11nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661969BDBM661969(2-fluoro-4-(6-(1-methyl-1H-indazol-5-yl)- 3-(piper...)
Affinity DataIC50: 11.8nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661968BDBM661968((S)-2-fluoro-4-(6-(4-methyl-3,4-dihydro- 2H-benzo[...)
Affinity DataIC50: 12nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661967BDBM661967((S)-2-fluoro-4-(6-(4-methyl-3,4-dihydro- 2H-benzo[...)
Affinity DataIC50: 12.1nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661973BDBM661973(4-(3-(azepan-4-ylmethyl)-6-(4-methyl-3,4- dihydro-...)
Affinity DataIC50: 13nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661970BDBM661970(4-(6-(1-methyl-1H-indazol-5-yl)-3- (piperidin-4-yl...)
Affinity DataIC50: 13.7nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661976BDBM661976(4-(6-(4-methyl-3,4-dihydro-2H- benzo[b][1,4]oxazin...)
Affinity DataIC50: 14.7nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661964BDBM661964(4-(6-(benzo[d][1,3]dioxol-5-yl)-3-((1- methylpiper...)
Affinity DataIC50: 15.7nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661972BDBM661972(4-(3-(azepan-4-ylmethyl)-6-(1-methyl-1H- indazol-5...)
Affinity DataIC50: 16.2nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661958BDBM661958(2-fluoro-4-(6-(4-methyl-3,4-dihydro-2H- benzo[b][1...)
Affinity DataIC50: 16.2nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661971BDBM661971(4-(3-(azepan-4-ylmethyl)-6-(1-methyl-1H- indazol-5...)
Affinity DataIC50: 17.3nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661965BDBM661965(4-(6-(benzo[d][1,3]dioxol-5-yl)-3-((1- methylpiper...)
Affinity DataIC50: 27.8nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661966BDBM661966((S)-2-fluoro-4-(6-(1-methyl-1H-indazol-5- yl)-3-((...)
Affinity DataIC50: 28nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661983BDBM661983(4-(6-(4-methyl-3,4-dihydro-2H- benzo[b][1,4]oxazin...)
Affinity DataIC50: 29.5nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661980BDBM661980((S)-4-(6-(1-methyl-1H-indazol-5-yl)-3- (pyrrolidin...)
Affinity DataIC50: 39.8nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661951BDBM661951(2-fluoro-4-(6-(1-methyl-1H-indazol-5-yl)- 3-((1-me...)
Affinity DataIC50: 40.1nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661979BDBM661979((S)-2-fluoro-4-(6-(4-methyl-3,4-dihydro- 2H-benzo[...)
Affinity DataIC50: 47nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661960BDBM661960(4-(6-(4-methyl-3,4-dihydro-2H- benzo[b][1,4]oxazin...)
Affinity DataIC50: 53.1nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661977BDBM661977((S)-2-fluoro-4-(6-(1-methyl-1H- pyrrolo[2,3-b]pyri...)
Affinity DataIC50: 53.3nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661956BDBM661956(4-(6-(1-methyl-1H-indazol-5-yl)-3-((1- methylpiper...)
Affinity DataIC50: 66.3nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661957BDBM661957(4-(6-(1-methyl-1H-indol-5-yl)-3-((1- methylpiperid...)
Affinity DataIC50: 68nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661981BDBM661981(4-(6-(1-methyl-1H-indazol-5-yl)-3-((1- methylpyrro...)
Affinity DataIC50: 87.2nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661962BDBM661962(2-fluoro-4-(6-(2-methyl-2H-indazol-5-yl)- 3-((1-me...)
Affinity DataIC50: 97.6nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661963BDBM661963(4-(6-(2-methyl-2H-indazol-5-yl)-3-((1- methylpiper...)
Affinity DataIC50: 115nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661961BDBM661961(4-(6-(1-ethyl-1H-indazol-5-yl)-3-((1- methylpiperi...)
Affinity DataIC50: 116nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661953BDBM661953(2-fluoro-4-(6-(1-methyl-2-oxoindolin-5- yl)-3-((1-...)
Affinity DataIC50: 220nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661952BDBM661952(2-fluoro-4-(6-(1-methyl-1H-indol-5-yl)-3- ((1-meth...)
Affinity DataIC50: 237nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661954BDBM661954(4-(6-(1-ethyl-1H-indazol-5-yl)-3-((1- methylpiperi...)
Affinity DataIC50: 372nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661955BDBM661955(2-fluoro-4-(6-(2-methylbenzo[d]thiazol-5- yl)-3-((...)
Affinity DataIC50: 928nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 661959BDBM661959(4,4'-(3-((1-methylpiperidin-4-yl)methyl)- 3H-imida...)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
US Patent