Compile Data Set for Download or QSAR
Report error Found 239 Enz. Inhib. hit(s) with all data for entry = 11972
TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326921BDBM326921(4-(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl...)
Affinity DataIC50: 0.0420nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326945BDBM326945(1-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.0700nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327137BDBM327137(4-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.0800nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327016BDBM327016((3S)-3-{4-[(1s,4s)-7- azabicyclo[2.2.1]hept-7- y...)
Affinity DataIC50: 0.0900nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326957BDBM326957(N-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.0900nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326992BDBM326992((3S)-3-[4-(azepan-1- ylmethyl)phenyl]-2,3- dihyd...)
Affinity DataIC50: 0.100nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327151BDBM327151(7-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.100nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327040BDBM327040(4-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.100nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326947BDBM326947(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.100nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326933BDBM326933([(3R)-1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- ...)
Affinity DataIC50: 0.110nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326997BDBM326997(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl]be...)
Affinity DataIC50: 0.120nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327156BDBM327156((1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl]b...)
Affinity DataIC50: 0.120nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326944BDBM326944(7-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.120nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327096BDBM327096(8-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyridin...)
Affinity DataIC50: 0.130nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327061BDBM327061(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.130nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327007BDBM327007(N-(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl...)
Affinity DataIC50: 0.130nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327068BDBM327068((3S)-3-{4-[(3-methoxypiperidin- 1-yl)methyl]phenyl...)
Affinity DataIC50: 0.130nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 667404BDBM667404(US11957671, Compound 224 | 1-{4-[(2S)-2,3-dihydro-...)
Affinity DataIC50: 0.130nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327133BDBM327133(4-[(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]p...)
Affinity DataIC50: 0.140nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327084BDBM327084((1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyridi...)
Affinity DataIC50: 0.140nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327085BDBM327085(N-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.140nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327012BDBM327012((3R)-1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]...)
Affinity DataIC50: 0.140nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327013BDBM327013((3S)-3-[4-(morpholin-4- ylmethyl)phenyl]-2,3- di...)
Affinity DataIC50: 0.150nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326973BDBM326973(8-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.150nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327153BDBM327153(3-[(4-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- y...)
Affinity DataIC50: 0.150nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327152BDBM327152(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.160nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326936BDBM326936(8-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.160nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326953BDBM326953(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.160nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327081BDBM327081(N-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.160nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327106BDBM327106(N-{l-[4-(2,3-dihydro-1,4- benzodioxin-2- yl)benz...)
Affinity DataIC50: 0.160nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327072BDBM327072(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyridin...)
Affinity DataIC50: 0.160nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327089BDBM327089(N-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.160nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327044BDBM327044(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.170nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327088BDBM327088(1-[(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyr...)
Affinity DataIC50: 0.170nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327004BDBM327004(N-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.170nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327111BDBM327111(N-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.170nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326988BDBM326988(N-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.180nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327091BDBM327091(N-cyclohexyl-N-{4-[(2S)-2,3- dihydro-1,4-benzodio...)
Affinity DataIC50: 0.180nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326940BDBM326940((3S)-3-[4-(pyrrolidin-1- ylmethyl)phenyl]-2,3- d...)
Affinity DataIC50: 0.180nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326983BDBM326983(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.180nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327064BDBM327064(N-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyridin...)
Affinity DataIC50: 0.180nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327076BDBM327076(N-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyri...)
Affinity DataIC50: 0.180nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 326980BDBM326980(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.190nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327021BDBM327021(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.190nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327052BDBM327052(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.200nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327003BDBM327003(N-(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl...)
Affinity DataIC50: 0.200nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327036BDBM327036((3S)-3-[4-(1,4-oxazepan-4- ylmethyl)phenyl]-2,3- ...)
Affinity DataIC50: 0.210nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327129BDBM327129(4-(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl...)
Affinity DataIC50: 0.220nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327059BDBM327059(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.220nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandChemical structure of BindingDB Monomer ID 327136BDBM327136(1-(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl...)
Affinity DataIC50: 0.220nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

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