Compile Data Set for Download or QSAR
Report error Found 820 Enz. Inhib. hit(s) with all data for entry = 11973
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667461BDBM667461(N-(3,6-dimethyl-9H- xanthen-9-yl)-5- (hydroxymethy...)
Affinity DataIC50: 10nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667751BDBM667751(N-(3,6-dimethyl-9H- thioxanthen-9-yl)-2-oxo-5- ((t...)
Affinity DataIC50: 10nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667458BDBM667458(N-(3,6-dimethyl-10,10- dioxido-9H-thioxanthen-9- y...)
Affinity DataIC50: 10nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667731BDBM667731(N-(3,6-dimethyl-9H- thioxanthen-9-yl)-6'-oxo-2'- (...)
Affinity DataIC50: 10nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667459BDBM667459(N-(3,6-dimethyl-9H- thioxanthen-9-yl)-2-oxo-6- (tr...)
Affinity DataIC50: 10nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667455BDBM667455(N-(3,6-dimethyl-9H- xanthen-9-yl)-2-oxo-5- (pyrimi...)
Affinity DataIC50: 10nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667473BDBM667473(N-(3,6-dimethyl-9H- xanthen-9-yl)-2-oxo-5- phenoxy...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667189BDBM667189(US11957687, Compound 182 | N-(3,6-dimethyl-9H- xan...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667198BDBM667198(US11957687, Compound 176 | N-(3,6-dimethyl-9H- xan...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667549BDBM667549(N-(3,6-dimethyl-9H- xanthen-9-yl)-2-oxo-5- ((tetra...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667450BDBM667450(5-benzyl-N-(3,6-dimethyl- 9H-xanthen-9-yl)-2-oxo-6...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667449BDBM667449(N-(3,6-dimethyl-9H- xanthen-9-yl)-2-oxo-5- propyl-...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667452BDBM667452(N-(3,6-dimethyl-9H- xanthen-9-yl)-2-oxo-5- pheneth...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667451BDBM667451(N-(3,6-dimethyl-9H- xanthen-9-yl)-6'-oxo-2'- (trif...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667483BDBM667483(N-(3,6-dimethyl-9H- xanthen-9-yl)-2',6-dioxo-2- (t...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667493BDBM667493(5-(cyclohexylamino)-N-(3,6- dimethyl-10,10-dioxido...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667305BDBM667305(US11957687, Compound 138 | N-(3-chloro-6-methyl-9H...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667464BDBM667464(N-(3,6-dimethyl-9H- xanthen-9-yl)-2-oxo-5- (pyrazi...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667469BDBM667469(N-(3,6-dimethyl-9H- xanthen-9-yl)-6-oxo-2- (triflu...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667466BDBM667466(N-(3,6-dimethyl-9H- xanthen-9-yl)-2'-methoxy-6- ox...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667541BDBM667541(5-cyclohexyl-N-(3,6- dimethyl-9H-xanthen-9-yl)- 2-...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667730BDBM667730(N-(3,6-dimethyl-9H- thioxanthen-9-yl)-2-oxo-5- phe...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667476BDBM667476(N-(3,6-dimethyl-9H- thioxanthen-9-yl)-6-oxo-2- (tr...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667188BDBM667188(US11957687, Compound 183 | 5-(cyclohex-1-en-1-yl)-...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667581BDBM667581(N-(3,6-dimethoxy-9H- thioxanthen-9-yl)-2-oxo-6- (t...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667481BDBM667481(5-bromo-N-(3,6-dimethyl- 10,10-dioxido-9H- thioxan...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667209BDBM667209(US11957687, Compound 173 | 5-allyl-N-(3,6-dichloro...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667688BDBM667688(US11957687, Compound 285 | N-(6-methyl-2-propyl- 1...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667463BDBM667463(N-(3,6-dimethyl-9H- xanthen-9-yl)-2-oxo-5- (pyrimi...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667758BDBM667758(N-(5-hydroxy-6-methyl- 1,2,3,4- tetrahydronaphthal...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667470BDBM667470(N-(3,6-dimethyl-10,10- dioxido-9H-thioxanthen-9- y...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667471BDBM667471(N-(3,6-dimethyl-9H- thioxanthen-9-yl)-5-methyl- 2-...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667468BDBM667468(N-(3,6-dimethyl-9H- xanthen-9-yl)-6,6'-dioxo-2- (t...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667605BDBM667605(US11957687, Compound 324 | N-(3-methyl-10H- chrome...)
Affinity DataIC50: 40nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667607BDBM667607(US11957687, Compound 385 | N-(2,7- dimethylthiochr...)
Affinity DataIC50: 40nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667490BDBM667490(5-(4-benzylpiperazin-1-yl)- N-(3,6-dimethyl-9H- xa...)
Affinity DataIC50: 40nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667518BDBM667518(N-(3,6-dimethyl-9H- thioxanthen-9-yl)-2-oxo-6- (tr...)
Affinity DataIC50: 40nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667517BDBM667517(N-(3,6-dimethyl-9H- xanthen-9-yl)-2-oxo-5- (tetrah...)
Affinity DataIC50: 40nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667631BDBM667631(N-(2-ethyl-6- methylthiochroman-4-yl)-2- oxo-6-(tr...)
Affinity DataIC50: 40nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667482BDBM667482(N-(3,6-dimethyl-9H- thioxanthen-9-yl)-2-oxo-5- (py...)
Affinity DataIC50: 40nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667609BDBM667609(US11957687, Compound 409 | N-(6-methyl-2,3,4,4a,9,...)
Affinity DataIC50: 40nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667197BDBM667197(US11957687, Compound 177 | N-(3,6-dimethyl-9H- xan...)
Affinity DataIC50: 40nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667637BDBM667637(N-(3-ethyl-6-methyl-1,2,3,4- tetrahydronaphthalen-...)
Affinity DataIC50: 50nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667621BDBM667621(US11957687, Compound 391 | N-(3,6-dimethyl-1,2,3,4...)
Affinity DataIC50: 50nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667441BDBM667441(5-allyl-N-(3,6-dimethyl-9H- xanthen-9-yl)-2-oxo-6-...)
Affinity DataIC50: 50nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667475BDBM667475(5-bromo-N-(3,6-dimethyl- 9H-thioxanthen-9-yl)-2-ox...)
Affinity DataIC50: 50nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667539BDBM667539(N-(3,6-dimethyl-9H- thioxanthen-9-yl)-5- (hydroxym...)
Affinity DataIC50: 50nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667437BDBM667437(N-(3,6-dimethyl-9H- xanthen-9-yl)-5- morpholino-2-...)
Affinity DataIC50: 50nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667629BDBM667629(N-(6-methyl-3-propyl- 1,2,3,4- tetrahydronaphthale...)
Affinity DataIC50: 50nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 667583BDBM667583(N-(2,7-dimethoxy-9H- fluoren-9-yl)-2-oxo-6- (trifl...)
Affinity DataIC50: 50nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

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