Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 11992
TargetTyrosine-protein kinase HCK(Human)
Flash Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 668506BDBM668506(US11963960, Example 163)
Affinity DataIC50: 1.10nMAssay Description:HCK kinase reaction (10 μL) containing 4 nM N-terminally GST-tagged HCK (75-526), purified from insect expression system, 5 μM Control AMC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2024
Entry Details
US Patent

TargetTyrosine-protein kinase HCK(Human)
Flash Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 8793BDBM8793(CHEMBL45177 | 7-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 3.30nMAssay Description:HCK kinase reaction (10 μL) containing 4 nM N-terminally GST-tagged HCK (75-526), purified from insect expression system, 5 μM Control AMC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2024
Entry Details
US Patent

TargetTyrosine-protein kinase HCK(Human)
Flash Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 668504BDBM668504(3-(2-Fluoro-4-phenoxyphenyl)-1-((trans)-4-(4-methy...)
Affinity DataIC50: 4.10nMAssay Description:HCK kinase reaction (10 μL) containing 4 nM N-terminally GST-tagged HCK (75-526), purified from insect expression system, 5 μM Control AMC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2024
Entry Details
US Patent

TargetTyrosine-protein kinase HCK(Human)
Flash Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 668505BDBM668505(US11963960, Example 165)
Affinity DataIC50: 5nMAssay Description:HCK kinase reaction (10 μL) containing 4 nM N-terminally GST-tagged HCK (75-526), purified from insect expression system, 5 μM Control AMC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2024
Entry Details
US Patent

TargetTyrosine-protein kinase HCK(Human)
Flash Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 668499BDBM668499(US11963960, Example 127)
Affinity DataIC50: 5.10nMAssay Description:HCK kinase reaction (10 μL) containing 4 nM N-terminally GST-tagged HCK (75-526), purified from insect expression system, 5 μM Control AMC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2024
Entry Details
US Patent

TargetTyrosine-protein kinase HCK(Human)
Flash Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 668510BDBM668510(US11963960, Example 17)
Affinity DataIC50: 16.5nMAssay Description:HCK kinase reaction (10 μL) containing 4 nM N-terminally GST-tagged HCK (75-526), purified from insect expression system, 5 μM Control AMC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2024
Entry Details
US Patent

TargetTyrosine-protein kinase HCK(Human)
Flash Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 668508BDBM668508(US11963960, Example 19)
Affinity DataIC50: 17nMAssay Description:HCK kinase reaction (10 μL) containing 4 nM N-terminally GST-tagged HCK (75-526), purified from insect expression system, 5 μM Control AMC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2024
Entry Details
US Patent

TargetTyrosine-protein kinase HCK(Human)
Flash Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 668509BDBM668509(US11963960, Example 21)
Affinity DataIC50: 43nMAssay Description:HCK kinase reaction (10 μL) containing 4 nM N-terminally GST-tagged HCK (75-526), purified from insect expression system, 5 μM Control AMC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2024
Entry Details
US Patent