Compile Data Set for Download or QSAR
Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 12028
TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670995BDBM670995(US11976059, Example 32)
Affinity DataIC50: 8nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670996BDBM670996(US11976059, Example 33)
Affinity DataIC50: 12nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670994BDBM670994(US11976059, Example 31)
Affinity DataIC50: 18nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671025BDBM671025(US11976059, Example 59)
Affinity DataIC50: 32nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671023BDBM671023(US11976059, Example 57)
Affinity DataIC50: 40nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671038BDBM671038(US11976059, Example 71)
Affinity DataIC50: 45nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671031BDBM671031(US11976059, Example 65)
Affinity DataIC50: 50nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671036BDBM671036(US11976059, Example 69)
Affinity DataIC50: 56nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671027BDBM671027(US11976059, Example 61)
Affinity DataIC50: 66nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671015BDBM671015(US11976059, Example 49)
Affinity DataIC50: 69nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671013BDBM671013(US11976059, Example 47)
Affinity DataIC50: 85nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670971BDBM670971(US11976059, Example 9)
Affinity DataIC50: 91nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670975BDBM670975(US11976059, Example 13)
Affinity DataIC50: 98nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670972BDBM670972(US11976059, Example 10 | US12391671, Compound 021)
Affinity DataIC50: 99nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671012BDBM671012(US11976059, Example 46)
Affinity DataIC50: 110nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671019BDBM671019(US11976059, Example 53)
Affinity DataIC50: 120nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670992BDBM670992(US11976059, Example 30)
Affinity DataIC50: 120nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670980BDBM670980(US11976059, Example 18)
Affinity DataIC50: 130nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670973BDBM670973(US11976059, Example 11)
Affinity DataIC50: 150nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670990BDBM670990(US11976059, Example 28)
Affinity DataIC50: 160nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670970BDBM670970(US11976059, Example 8)
Affinity DataIC50: 170nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670988BDBM670988(US11976059, Example 26)
Affinity DataIC50: 190nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671026BDBM671026(US11976059, Example 60)
Affinity DataIC50: 190nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671010BDBM671010(US11976059, Example 44)
Affinity DataIC50: 190nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671009BDBM671009(US11976059, Example 43)
Affinity DataIC50: 210nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671006BDBM671006(US11976059, Example 41)
Affinity DataIC50: 220nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671020BDBM671020(US11976059, Example 54)
Affinity DataIC50: 240nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671035BDBM671035(US11976059, Example 68)
Affinity DataIC50: 250nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671030BDBM671030(US11976059, Example 64)
Affinity DataIC50: 260nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670989BDBM670989(US11976059, Example 27)
Affinity DataIC50: 280nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670991BDBM670991(US11976059, Example 29)
Affinity DataIC50: 280nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671011BDBM671011(US11976059, Example 45)
Affinity DataIC50: 280nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671029BDBM671029(US11976059, Example 63)
Affinity DataIC50: 300nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671005BDBM671005(US11976059, Example 40)
Affinity DataIC50: 370nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671032BDBM671032(US11976059, Example 66)
Affinity DataIC50: 410nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671016BDBM671016(US11976059, Example 50)
Affinity DataIC50: 420nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671007BDBM671007(US11976059, Example 42)
Affinity DataIC50: 450nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671022BDBM671022(US11976059, Example 56)
Affinity DataIC50: 450nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671021BDBM671021(US11976059, Example 55)
Affinity DataIC50: 480nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670974BDBM670974(US11976059, Example 12)
Affinity DataIC50: 500nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671017BDBM671017(US11976059, Example 51)
Affinity DataIC50: 650nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670969BDBM670969(US11976059, Example 7)
Affinity DataIC50: 700nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670998BDBM670998(US11976059, Example 35)
Affinity DataIC50: 730nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671037BDBM671037(US11976059, Example 70)
Affinity DataIC50: 730nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671034BDBM671034(US11976059, Example 67)
Affinity DataIC50: 790nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 671003BDBM671003(US11976059, Example 39 | US12391671, Compound 059)
Affinity DataIC50: 960nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670963BDBM670963(US11976059, Example 1)
Affinity DataIC50: 1.00E+3nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670979BDBM670979(US11976059, Example 17)
Affinity DataIC50: 1.10E+3nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670976BDBM670976(US11976059, Example 14)
Affinity DataIC50: 1.30E+3nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 670982BDBM670982(US11976059, Example 20)
Affinity DataIC50: 1.60E+3nMAssay Description:The composition of the assay buffer used for the activity measurement was as follows: 50 mM Tris-HCl (pH 7.5), 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2024
Entry Details
US Patent

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